期刊
DERMATOLOGIC THERAPY
卷 34, 期 6, 页码 -出版社
WILEY
DOI: 10.1111/dth.15160
关键词
antioxidants; atopic dermatitis; oxidative stress; psoriasis; supplementation; Vitamin E
类别
Vitamin E is a powerful antioxidant that protects against oxidative damage and neurodegenerative diseases. Supplementation of vitamin E can be beneficial in certain cases and chronic diseases. While some studies suggest a positive role of vitamin E in atopic dermatitis and psoriasis, further research is needed to confirm its efficacy.
Vitamin E is a powerful lipophilic antioxidant that protects membranes from lipid peroxidation, and consequently, oxidative damage. Oxidative stress plays a role in the development of neurodegenerative diseases. Vitamin E supplementation is recommended in patients with vitamin E deficiency due to fat malabsorption. The addition of vitamin E to the diet slows Alzheimer's disease progression and protects older patients against respiratory infections. Recent studies also point to the involvement of oxidative stress in the pathology of immune-mediated skin diseases, such as atopic dermatitis and psoriasis. We reviewed the available clinical trials that investigated the role of vitamin E supplementation in preventing and treating atopic dermatitis and psoriasis. Data from these studies point to a positive role of vitamin E supplementation in these diseases. Still, due to limitations in study design, further evidence is needed to reach a definite conclusion.
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