Proactive therapy: New perspectives for long-term topical treatment of psoriasis

Mild to moderate psoriasis is most often treated with topical therapy. The article reviews literature on topical treatments that have been assessed in clinical trials and real-life studies lasting at least 12 months. Calcipotriol/bethamethasone dipropionate foam in maintenance treatment following the induction phase can improve efficacy and safety of topical therapy in psoriatic patients. Introduction of new topical nonsteroidal drugs and the wider use of proactive therapy seem to be crucial to achieve satisfactory long-term outcomes in psoriasis.

Automated summary

Mild to moderate psoriasis is commonly treated with topical therapy. This article reviews literature on topical treatments that have been evaluated in clinical trials and real-life studies lasting at least 12 months. The use of calcipotriol/bethamethasone dipropionate foam as maintenance treatment can improve the efficacy and safety of topical therapy in psoriatic patients. Introducing new nonsteroidal topical drugs and adopting proactive therapy appear to be crucial for achieving satisfactory long-term outcomes in psoriasis.