期刊
CURRENT TREATMENT OPTIONS IN ONCOLOGY
卷 23, 期 1, 页码 68-77出版社
SPRINGER
DOI: 10.1007/s11864-022-00943-7
关键词
Soft tissue sarcoma; Preoperative radiation therapy; Omission of radiation therapy; Dose deintensification; Hypofractionation; Combination therapy
类别
Preoperative radiation therapy is an important component of curative treatment for soft tissue sarcomas, and innovative strategies have been developed to individualize the treatment approach.
Opinion statement Preoperative radiation therapy is an important component of curative treatment for extremity and superficial trunk soft tissue sarcomas. It has traditionally been delivered to a dose of 50 Gy in 2 Gy fractions over 5 weeks. With significant advances in the multidisciplinary approach to soft tissue sarcomas, preoperative radiation therapy may be omitted for certain cases, delivered over a shortened period of time (1-3 weeks), deintensified for myxoid liposarcomas, or combined with systemic therapy to improve the therapeutic ratio. This article reviews the innovative preoperative radiation therapy strategies currently used to treat extremity and superficial trunk soft tissue sarcomas.
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