4.7 Review

Auxin canalization: From speculative models toward molecular players

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Article Biochemistry & Molecular Biology

Auxin-Regulated Reversible Inhibition of TMK1 Signaling by MAKR2 Modulates the Dynamics of Root Gravitropism

Maria Mar Marques-Bueno et al.

Summary: Plants can adjust their growth direction according to gravity by utilizing asymmetric distribution of the plant hormone auxin, which is dependent on the activity of polarly localized PIN-FORMED (PIN) auxin-efflux carriers.

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Shutang Tan et al.

Summary: The plant hormone auxin is central to plant growth and development, with protein phosphorylation emerging as a crucial post-translational modification type regulating auxin output. This review comprehensively discusses the genetics, biochemistry, and cell biology of kinases and phosphatases involved in auxin action, providing insights into the mechanisms of developmental auxin responses and future directions for integrating protein phosphorylation control into the molecular auxin network.

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Of Cells, Strands, and Networks: Auxin and the Patterned Formation of the Vascular System

Dhruv Lavania et al.

Summary: The formation of the plant vascular system is a dynamic process in which auxin plays a crucial role. Cells compete and select each other based on an auxin-dependent signal, leading to the gradual formation of continuous vascular cell strands.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2021)

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AGC kinases and MAB4/MEL proteins maintain PIN polarity by limiting lateral diffusion in plant cells

Matous Glanc et al.

Summary: Through protein biochemistry and quantitative live-cell imaging, it was found that PINs, MAB4/MELs, and AGC kinases interact in the same complex at the plasma membrane, contributing to maintaining the polarity of PINs by limiting their escape from the polar domain through lateral diffusion. Positive feedback between AGC kinase-mediated PIN phosphorylation and MAB4/MEL recruitment in the PIN-MAB4/MEL-PID protein complex reinforces their regulation of PIN localization and plant development.

CURRENT BIOLOGY (2021)

Article Cell Biology

The Story of Auxin-Binding Protein 1 (ABP1)

Richard Napier

Summary: ABP1, the auxin-binding protein, has been debated as a candidate receptor for auxin signaling. Despite its ability to bind auxin, its relevance to plant development and signaling remains to be fully defined. Research has shown associations between ABP1 and various auxin-induced activities, but studies also suggest that its auxin-binding capacity may not be physiologically relevant.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2021)

Article Plant Sciences

Systematic analysis of specific and nonspecific auxin effects on endocytosis and trafficking

Madhumitha Narasimhan et al.

Summary: This study reexamined the effects of auxin on PIN endocytic trafficking and found that high concentrations of NAA and IAA have nonspecific effects on the endomembrane system, while low concentrations specifically promoted endocytosis of PIN2. This contributes to polarity maintenance and highlights the nonspecific effects of high auxin levels on trafficking and endomembrane compartments.

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The canalization hypothesis - challenges and alternatives

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Receptor kinase module targets PIN-dependent auxin transport during canalization

Jakub Hajny et al.

SCIENCE (2020)

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Calcium signals are necessary to establish auxin transporter polarity in a plant stem cell niche

Ting Li et al.

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AUX1-mediated root hair auxin influx governs SCFTIR1/AFB-type Ca2+ signaling

Julian Dindas et al.

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Maternal auxin supply contributes to early embryo patterning in Arabidopsis

Helene S. Robert et al.

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Vascular cambium regeneration and vessel formation in wounded inflorescence stems of Arabidopsis

Ewa Mazur et al.

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Auxin-driven patterning with unidirectional fluxes

Mikolaj Cieslak et al.

JOURNAL OF EXPERIMENTAL BOTANY (2015)

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PIN-Dependent Auxin Transport: Action, Regulation, and Evolution

Maciek Adamowski et al.

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Cell Surface ABP1-TMK Auxin-Sensing Complex Activates ROP GTPase Signaling

Tongda Xu et al.

SCIENCE (2014)

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Canalization: what the flux?

Tom Bennett et al.

TRENDS IN GENETICS (2014)

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Modeling Framework for the Establishment of the Apical-Basal Embryonic Axis in Plants

Krzysztof Wabnik et al.

CURRENT BIOLOGY (2013)

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Emergence of tissue polarization from synergy of intracellular and extracellular auxin signaling

Krzysztof Wabnik et al.

MOLECULAR SYSTEMS BIOLOGY (2010)

Article Multidisciplinary Sciences

ADP-ribosylation factor machinery mediates endocytosis in plant cells

Satoshi Naramoto et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Polar PIN localization directs auxin flow in plants

J Wisniewska et al.

SCIENCE (2006)

Article Cell Biology

Control of leaf vascular patterning by polar auxin transport

E Scarpella et al.

GENES & DEVELOPMENT (2006)

Article Multidisciplinary Sciences

Auxin inhibits endocytosis and promotes its own efflux from cells

T Paciorek et al.

NATURE (2005)

Article Biochemistry & Molecular Biology

Local, efflux-dependent auxin gradients as a common module for plant organ formation

E Benková et al.