期刊
CURRENT OPINION IN INFECTIOUS DISEASES
卷 35, 期 2, 页码 88-94出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/QCO.0000000000000816
关键词
coronavirus disease 2019; cutaneous manifestations; erythematous rashes; severe acute respiratory syndrome coronavirus-2; vascular lesions; vesicular rashes
Recent studies have shown an increasing number of patients reporting polymorphic cutaneous manifestations during COVID-19, although the pathogenesis of these skin manifestations is still not fully understood.
Purpose of reviewCoronavirus disease 2019 (COVID-19) is a well established respiratory tract illness. Recent studies in adults and children have shown an increasing number of patients reporting polymorphic cutaneous manifestations during COVID-19, including different types of rashes, from maculopapular, vascular, vesicular to atypical forms.Recent findingsAlthough pathogenesis of skin manifestations is still not fully understood, it has been proposed that cutaneous involvement during COVID-19 may be the results of the activation of the immune response against severe acute respiratory syndrome coronavirus-2, the reactivation or co-infection of herpesviruses or drug hypersensitivity.According to available literature, skin manifestations in patients with COVID-19 may be categorized on the basis of their clinical presentations as follows: erythematous rashes, lesions of vascular origin, vesicular rash, urticarial rash and acute generalized exanthematous pustulosis (AGEP), erythema multiforme and other polymorphic erythema/atypical reactions. Prompt recognition of these cutaneous manifestations represents a crucial point to facilitate diagnosis and management of COVID-19 patients.
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