Caged lipids for subcellular manipulation

We present recently developed strategies to manipulate lipid levels in live cells by light. We focus on photoremovable protecting groups that lead to subcellular restricted localization and activation and discuss alternative techniques. We emphasize the development of organelle targeting of caged lipids and discuss recent advances in chromatic orthogonality of caging groups for future applications.

Automated summary

This study introduces strategies to manipulate lipid levels in live cells by light, focusing on photoremovable protecting groups for subcellular restricted localization and activation, along with alternative techniques and organelle targeting development. Recent advances in chromatic orthogonality of caging groups for future applications are also discussed.