☆ 4.1 Review

Exposure to nanoparticles and occupational allergy

CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY (2022)

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Review Pharmacology & Pharmacy

Mechanisms of immune response to inorganic nanoparticles and their degradation products

Raziye Mohammapdour et al.

Summary: Research has elucidated the cellular and molecular mechanisms of interaction between inorganic nanoparticles and the immune system, with a specific focus on the immune response to the degradation products. The importance of designing new methods and instruments for assessing the safety of inorganic nanoparticles was emphasized.

ADVANCED DRUG DELIVERY REVIEWS (2022)

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Review Environmental Sciences

Association between exposure to air pollution and risk of allergic rhinitis: A systematic review and meta-analysis

Sai Li et al.

Summary: This meta-analysis demonstrates a positive association between air pollution and the prevalence of allergic rhinitis, with children or adolescents being more sensitive to air pollution than adults. The effects of PM10 and SO2 were significantly stronger in Europe than in Asia, and the impact of air pollutants was more significant in developing countries compared to developed countries.

ENVIRONMENTAL RESEARCH (2022)

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Article Allergy

Application of the adverse outcome pathway framework for investigating skin sensitization potential of nanomaterials using new approach methods

Soraia F. Bezerra et al.

Summary: The study reveals that nanomaterials can easily internalize into keratinocytes cells, interact with skin proteins, and induce activation of U937 cells by increasing CD86 expression and modulating inflammatory cytokine production, leading to their classification as skin sensitizers in vitro. This highlights the importance of studying the immunotoxicity and skin sensitization potential of nanomaterials to anticipate possible human health risks and contribute toward the applicability of existing OECD testing guidelines.

CONTACT DERMATITIS (2021)

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Letter Allergy

Chronic exposure to benzo(a)pyrene-coupled nanoparticles worsens inflammation in a mite-induced asthma mouse model

Julie Carrard et al.

ALLERGY (2021)

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Review Pharmacology & Pharmacy

Nanoparticle Toxicology

Wen Yang et al.

Summary: This article reviews the potential adverse effects of nanoparticles on human health and discusses mechanisms of nanotoxicity, including the generation of reactive oxygen species, nanoparticle disintegration, and modulation of cell signaling pathways. Improved understanding of nanoparticle toxicity may lead to strategies for safe application of nanotechnology.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 61, 2021 (2021)

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Article Engineering, Environmental

Association of airborne particulate matter with pollen, fungal spores, and allergic symptoms in an arid urbanized area

C. I. Ortega-Rosas et al.

Summary: The study suggests that climate-driven dust emissions may alter the physicochemical characteristics of pollen and spores surfaces, potentially affecting their allergenic potential. Particles from geogenic origin mixed with metals linked to traffic were found to attach to pollen surfaces, forming micro- to nanoparticles. It was also discovered that two local soil types are the main contributors to PM in the urban atmosphere.

ENVIRONMENTAL GEOCHEMISTRY AND HEALTH (2021)

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Article Toxicology

Structural and biochemical modifications of model and native membranes of human immune cells in response to the action of zinc oxide nanoparticles

Agnieszka Czyzowska et al.

Summary: The study aimed to assess the toxic effects of ZnO-NPs on model human immune cells, focusing on their interaction with membrane lipids and the role of zinc ions. Results showed disruption in cell metabolism and lipid peroxidation, with zinc ions not being the main causative factor of toxicity. Using Langmuir technique, the interaction of nanoparticles with lipids was evaluated to understand the early stages of toxicity mechanism for a complete risk assessment and safer synthesis of nanomaterials.

JOURNAL OF APPLIED TOXICOLOGY (2021)

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Article Environmental Sciences

Personal exposure to average weekly ultrafine particles, lung function, and respiratory symptoms in asthmatic and non-asthmatic adolescents

Ashley Turner et al.

ENVIRONMENT INTERNATIONAL (2021)

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Article Biochemistry & Molecular Biology

Titanium dioxide particles modulate epithelial barrier protein, Claudin 7 in asthma

Yun-Gi Lee et al.

Summary: The study found that TiO2 suppresses the expression of CLDN7, leading to lower levels of CLDN7 in the plasma of patients with asthma. CLDN7 levels were associated with lung function and blood eosinophils in asthma patients.

MOLECULAR IMMUNOLOGY (2021)

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Article Medicine, Research & Experimental

Particulate matter causes skin barrier dysfunction

Byung Eui Kim et al.

Summary: The study revealed that PM2.5 can inhibit FLG and other proteins in the stratum corneum, compromising skin barrier function and increasing skin permeability, potentially contributing to the development and exacerbation of allergic diseases.

JCI INSIGHT (2021)

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Article Immunology

Vps33B in Dendritic Cells Regulates House Dust Mite-Induced Allergic Lung Inflammation

Jingyu Ma et al.

Summary: This study shows that the absence of Vps33B in DCs exacerbates Th2-mediated allergic lung inflammation, revealing the regulatory role of cross-talk between DCs and CD4(+) T cells in the pathogenesis of allergic asthma.

JOURNAL OF IMMUNOLOGY (2021)

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Review Dermatology

Allergic contact dermatitis: a significant environmental and occupational skin disease

Olufunmilayo A. Olusegun et al.

Summary: ACD is a significant skin disease with environmental and occupational causes, which can impact patients' quality of life. Understanding and raising awareness of ACD can help reduce its psychological and social effects on patients.

INTERNATIONAL JOURNAL OF DERMATOLOGY (2021)

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Article Pharmacology & Pharmacy

Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice

Mariana Garces et al.

Summary: This study aimed to investigate the toxicological mechanisms in cardiorespiratory oxidative metabolism induced by acute exposure to Ni-doped-NP. Results showed that Ni-NP mainly accumulated in the lungs, leading to increased oxidative reactions and damage to the antioxidant system, resulting in various pathological responses.

TOXICOLOGY (2021)

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Review Chemistry, Multidisciplinary

The Interactions between Nanoparticles and the Innate Immune System from a Nanotechnologist Perspective

Lena M. Ernst et al.

Summary: The immune system plays a crucial role in maintaining the body's functional integrity by recognizing and destroying foreign agents and abnormal cells. Nanoparticles can interact with the immune system in complex ways, potentially leading to different immune responses.

NANOMATERIALS (2021)

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Article Chemistry, Multidisciplinary

Structure-Activity Relationship of Graphene-Based Materials: Impact of the Surface Chemistry, Surface Specific Area and Lateral Size on Their In Vitro Toxicity

Salma Achawi et al.

Summary: The study found that reduced graphene oxides (RGOs) were more reactive than graphene nanoplatelets (GNPs), and smaller lateral size led to higher cytotoxicity. GBMs with a higher specific surface area were found to induce higher ROS production.

NANOMATERIALS (2021)

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Article Biochemistry & Molecular Biology

Metallobiochemistry of ultratrace levels of bismuth in the rat I. Metabolic patterns of 205+206Bi3+ in the blood

Enrico Sabbioni et al.

Summary: The study focuses on the metabolic fate of ultratrace levels of Bi205+206(NO)(3) in the blood of rats, revealing insights into the distribution and binding of bismuth in different blood compartments, such as plasma and red blood cells. It also highlights the complexation of bismuth at physiological pH and the role of various biomolecules, such as transferrin and albumin, in carrying bismuth ions in the blood.

JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY (2021)

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Article Toxicology

Effects of metal nanoparticles on tight junction-associated proteins via HIF-1α/miR-29b/MMPs pathway in human epidermal keratinocytes

Jiali Yuan et al.

Summary: The study demonstrated that exposure of human epidermal keratinocytes to Nickel nanoparticles caused dysregulation of tight junction-associated proteins and down-regulation of miR-29b, while leading to increased HIF-1 alpha nuclear accumulation and MMP-2/9 activation. Restoring miR-29b levels with a miR-29b-3p mimic reversed the effects induced by Nano-Ni, indicating a pathway of HIF-1 alpha/miR-29b/MMPs in the dysregulation of tight junction-associated proteins.

PARTICLE AND FIBRE TOXICOLOGY (2021)

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Article Chemistry, Multidisciplinary

Effect of Graphene and Graphene Oxide on Airway Barrier and Differential Phosphorylation of Proteins in Tight and Adherens Junction Pathways

Sofie Van Den Broucke et al.

Summary: This study investigated the impact of environmental and occupational irritants on the airway epithelial barrier using an in vitro coculture model. The findings suggest that graphene nanoparticles have a negative effect on the epithelial barrier, possibly due to slight alterations in tight junction organization.

NANOMATERIALS (2021)

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Article Engineering, Biomedical

Exposure to hydroxyapatite nanoparticles enhances Toll-like receptor 4 signal transduction and overcomes endotoxin tolerance in vitro and in vivo

Yuchen Hua et al.

Summary: The study reveals that HANPs can induce TLR4 signaling activation and synergize with LPS to promote macrophage polarization toward M1 phenotype, as well as to abolish immune tolerance in response to repeated LPS stimulation.

ACTA BIOMATERIALIA (2021)

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Review Allergy

Dysregulation of the epithelial barrier by environmental and other exogenous factors

Yasutaka Mitamura et al.

Summary: The epithelial barrier hypothesis suggests that exposure to various barrier-damaging agents is linked to the increase in allergic diseases. The epithelial barrier is the first line of defense against environmental factors and disruption by industrial products. Innate and adaptive immune responses are essential in barrier damage, and understanding this mechanism is key in developing strategies for prevention and treatment of allergic diseases. Monitoring skin barrier dysfunction as a biomarker and studying the role of external factors in disrupting the epithelial barrier are crucial in this field.

CONTACT DERMATITIS (2021)

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Article Biochemistry & Molecular Biology

Airway Exposure to Polyethyleneimine Nanoparticles Induces Type 2 Immunity by a Mechanism Involving Oxidative Stress and ATP Release

Yotesawee Srisomboon et al.

Summary: PEI induces immune responses by stimulating ATP release, activating VDAC-1 and pannexin 1 pathways, and increasing intracellular Ca2+ concentration. In vivo experiments show that PEI exposure leads to Th2 cytokine secretion and eosinophil recruitment, with IL-33 playing a crucial role in this process.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

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Article Nanoscience & Nanotechnology

Physical properties of gold nanoparticles affect skin penetration via hair follicles

Nethanel Friedman et al.

Summary: Drug penetration through the skin can be significantly influenced by particle size, with gold nanostars showing superiority over spherical particles in follicular penetration experiments. Understanding the optimal physical particle properties is crucial for improving drug delivery methods.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2021)

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Article Chemistry, Multidisciplinary

Size-Dependent Absorption through Stratum Corneum by Drug-Loaded Liposomes

Junye Liu et al.

Summary: The size of liposomes has an impact on drug absorption and distribution in skin tissues. Liposomes smaller than 100 nm improve drug delivery to the epidermis and dermis, while liposomes larger than 200 nm have poor penetration through the SC structure.

PHARMACEUTICAL RESEARCH (2021)

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Article Oncology

An updated overview on metal nanoparticles toxicity

Serenella Medici et al.

Summary: Despite the increasing number and variety of nanoparticles, there is still a lack of clear guidelines to control their exposure and evaluate potential toxicity. The issue of nanomaterials' toxicity is gaining awareness among scientists and producers, yet consumers often remain largely unaware of the presence and potential risks of nanomaterials.

SEMINARS IN CANCER BIOLOGY (2021)

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Review Public, Environmental & Occupational Health

Toxicity risks of occupational exposure in 3D printing and bioprinting industries: A systematic review

Yousef Mohammadian et al.

Summary: 3D printing and bioprinting technologies use synthetic and natural polymers respectively, which may release VOCs and nanoparticles with toxic effects. Further research and attention to occupational exposure risk are needed to ensure safety in workplaces.

TOXICOLOGY AND INDUSTRIAL HEALTH (2021)

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Review Environmental Sciences

Effects of Air Pollutants on Airway Diseases

Yun-Gi Lee et al.

Summary: Air pollutants, including toxic particles and gases, aggravate respiratory diseases such as asthma and COPD by triggering inflammation and dysfunction in the airways, leading to worsening symptoms. The mechanisms underlying these effects are still unclear, but air pollution is known to decrease quality of life and life expectancy while increasing the risk of hospitalization and morbidity associated with respiratory diseases.

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH (2021)

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Review Chemistry, Multidisciplinary

Current Knowledge of Silver and Gold Nanoparticles in Laboratory Research-Application, Toxicity, Cellular Uptake

Patrycja Talarska et al.

Summary: Silver and gold nanoparticles are widely used in various household products, raising concerns about their potential impact. Research is focusing on the effects of nanoparticles on cell function and environmentally friendly alternatives to chemically synthesized nanoparticles.

NANOMATERIALS (2021)

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Article Chemistry, Multidisciplinary

Skin Sensitization Potential and Cellular ROS-Induced Cytotoxicity of Silica Nanoparticles

Sung-Hyun Kim et al.

Summary: With the rapid growth of nanomaterials in various industries, particularly in cosmetics, there is a need for accurate identification of their toxicity. This study focused on silica nanoparticles and found high cytotoxicity but no skin sensitization. Further research is needed to clarify the mechanism of skin sensitization by nanomaterials.

NANOMATERIALS (2021)

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Article Chemistry, Multidisciplinary

The nanotopography of SiO2 particles impacts the selectivity and 3D fold of bound allergens

Robert Mills-Goodlet et al.

Summary: The detailed description of the changes during protein corona formation is crucial in understanding the impact on nanoparticle behavior and bound proteins. Nanotopography, specifically the porosity of the nanoparticles, plays a significant role in allergen binding selectivity, orientation preference, conformational changes, and allergenic response. Thorough structural investigations are important for considering immunological outcomes, as particle binding can influence the allergenic response elicited by the bound allergen.

NANOSCALE (2021)

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Review Allergy

The Impact of Environmental Pollutants on Barrier Dysfunction in Respiratory Disease

Pureun-Haneul Lee et al.

Summary: Respiratory epithelial cells form a selective barrier between the outside environment and underlying tissues, and the assembly and disassembly of the apical junctional complex (AJC) play a crucial role in regulating cell morphology. Biological contaminants and air pollutants exacerbate the onset of respiratory diseases by affecting the cell barrier.

ALLERGY ASTHMA & IMMUNOLOGY RESEARCH (2021)

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Review Public, Environmental & Occupational Health

Occupational Exposures to Engineered Nanomaterials: a Review of Workplace Exposure Assessment Methods

Seth McCormick et al.

Summary: This review consolidates exposure assessment methods for occupational research on engineered nanomaterials (ENMs) within the past 5 years, highlighting the most commonly used materials and methods, emphasizing the importance of combining online and offline instruments and analyses, and pointing out the lack of consensus methods for offline analyses of most ENMs.

CURRENT ENVIRONMENTAL HEALTH REPORTS (2021)

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Article Biophysics

Can the biomolecular corona induce an allergic reaction?-A proof-of-concept study

Anne Muehe et al.

Summary: The study aimed to investigate whether patients with or without hypersensitivity reactions to ferumoxytol nanoparticles develop specific protein corona profiles. The results suggest that analyzing the biomolecular corona ex vivo may provide predictive information on severe allergic reactions to ferumoxytol nanoparticles, potentially allowing for the diagnosis of patients predisposed to an allergic reaction based on proteomic patterns in the corona.

BIOINTERPHASES (2021)

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Review Pharmacology & Pharmacy

Recent advances in follicular drug delivery of nanoparticles

Alexa Patzelt et al.

EXPERT OPINION ON DRUG DELIVERY (2020)

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Review Biochemistry & Molecular Biology

Mechanisms of ultrafine particle-induced respiratory health effects

George D. Leikauf et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2020)

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Review Immunology

Nanoparticle-based immunotherapy: state of the art and future perspectives

Mario Di Gioacchino et al.

EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2020)

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Article Chemistry, Multidisciplinary

How to Address the Adjuvant Effects of Nanoparticles on the Immune System

Alexia Feray et al.

NANOMATERIALS (2020)

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Review Immunology

Engineered Nanomaterials and Type I Allergic Hypersensitivity Reactions

Nasser B. Alsaleh et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Pharmacology & Pharmacy

Nanoscale investigation of human skin and study of skin penetration of Janus nanoparticles

Kamilia Kemel et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

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Review Chemistry, Multidisciplinary

Nanomaterial Transformations in the Environment: Effects of Changing Exposure Forms on Bioaccumulation and Toxicity

David J. Spurgeon et al.

SMALL (2020)

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Review Immunology

Mechanisms of Particles in Sensitization, Effector Function and Therapy of Allergic Disease

Anna I. Joubert et al.

FRONTIERS IN IMMUNOLOGY (2020)

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Article Allergy

Environmental factors in epithelial barrier dysfunction

Zeynep Celebi Soezener et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

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Review Allergy

Cutaneous barrier dysfunction in allergic diseases

Donald Y. M. Leung et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2020)

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Review Biochemistry & Molecular Biology

Atomic Details of Carbon-Based Nanomolecules Interacting with Proteins

Luigi Di Costanzo et al.

MOLECULES (2020)

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Review Toxicology

Recent insights on indirect mechanisms in developmental toxicity of nanomaterials

Battuja Batbajar Dugershaw et al.

PARTICLE AND FIBRE TOXICOLOGY (2020)

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Article Nanoscience & Nanotechnology

Evaluation of the skin-sensitizing potential of gold nanoparticles and the impact of established dermal sensitivity on the pulmonary immune response to various forms of gold

K. A. Roach et al.

NANOTOXICOLOGY (2020)

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Article Respiratory System

High-dose intranasal application of titanium dioxide nanoparticles induces the systemic uptakes and allergic airway inflammation in asthmatic mice

Shaza Abdulnasser Harfoush et al.

RESPIRATORY RESEARCH (2020)

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Article Respiratory System

Outdoor Air Pollution and New-Onset Airway Disease An Official American Thoracic Society Workshop Report

George D. Thurston et al.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2020)

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Article Pharmacology & Pharmacy

Quantum dots and mouse strain influence house dust mite-induced allergic airway disease

David K. Scoville et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2019)

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Article Pharmacology & Pharmacy

Exposure to silver nanoparticles primes mast cells for enhanced activation through the high-affinity IgE receptor

Nasser B. Alsaleh et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2019)

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Article Allergy

Occupational immunologic lung disease

Dawn K. Lei et al.

ALLERGY AND ASTHMA PROCEEDINGS (2019)

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Review Biochemistry & Molecular Biology

Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review

Keywan Mortezaee et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2019)

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Article Biochemistry & Molecular Biology

Cerium Oxide Nanoparticles Absorption through Intact and Damaged Human Skin

Marcella Mauro et al.

MOLECULES (2019)

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Article Toxicology

Multi-walled carbon nanotube oxidation dependent keratinocyte cytotoxicity and skin inflammation

Brian C. Palmer et al.

PARTICLE AND FIBRE TOXICOLOGY (2019)

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Article Respiratory System

Airway inflammation after inhalation of nano-sized zinc oxide particles in human volunteers

Christian Monse et al.

BMC PULMONARY MEDICINE (2019)

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Review Toxicology

Metal nanomaterials: Immune effects and implications of physicochemical properties on sensitization, elicitation, and exacerbation of allergic disease

Katherine A. Roach et al.

JOURNAL OF IMMUNOTOXICOLOGY (2019)

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Article Toxicology

Subchronic exposure to palladium nanoparticles affects serum levels of cytokines in female Wistar rats

I. Iavicoli et al.

HUMAN & EXPERIMENTAL TOXICOLOGY (2018)

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Article Biophysics

Synchrotron-based X-ray fluorescence study of gold nanorods and skin elements distribution into excised human skin layers

Nouf N. Mahmoud et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2018)

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Article Toxicology

Association of pulmonary, cardiovascular, and hematologic metrics with carbon nanotube and nanofiber exposure among US workers: a cross-sectional study

Mary K. Schubauer-Berigan et al.

PARTICLE AND FIBRE TOXICOLOGY (2018)

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Article Toxicology

Cerium dioxide nanoparticles exacerbate house dust mite induced type II airway inflammation

Kirsty Meldrum et al.

PARTICLE AND FIBRE TOXICOLOGY (2018)

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Review Toxicology

Chemical-induced contact allergy: from mechanistic understanding to risk prevention

Emanuela Corsini et al.

ARCHIVES OF TOXICOLOGY (2018)

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Article Public, Environmental & Occupational Health

The Toxicology of Engineered Nanomaterials in Asthma

Mark D. Ihrie et al.

CURRENT ENVIRONMENTAL HEALTH REPORTS (2018)

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Article Chemistry, Multidisciplinary

5 nm Silver Nanoparticles Amplify Clinical Features of Atopic Dermatitis in Mice by Activating Mast Cells

HanGoo Kang et al.

SMALL (2017)

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Review Biochemistry & Molecular Biology

Oxidative Stress: Promoter of Allergic Sensitization to Protease Allergens?

Leonie S. van Rijt et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

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Article Chemistry, Multidisciplinary

The effect of different workplace nanoparticles on the immune systems of employees

Natalja Kurjane et al.

JOURNAL OF NANOPARTICLE RESEARCH (2017)

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Article Public, Environmental & Occupational Health

Immunological effects among workers who handle engineered nanoparticles

Deborah Catherine Glass et al.

OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2017)

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Review Immunology

Nanomaterials in the Context of Type 2 Immune Responses-Fears and Potentials

Martin Himly et al.

FRONTIERS IN IMMUNOLOGY (2017)

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Article Multidisciplinary Sciences

Immunomodulatory Effects of Nanoparticles on Skin Allergy

Samreen Jatana et al.

SCIENTIFIC REPORTS (2017)

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Review Respiratory System

Current and new challenges in occupational lung diseases

Sara De Matteis et al.

EUROPEAN RESPIRATORY REVIEW (2017)

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Article Biochemistry & Molecular Biology

Size-Limited Penetration of Nanoparticles into Porcine Respiratory Mucus after Aerosol Deposition

Xabier Murgia et al.

BIOMACROMOLECULES (2016)

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Article Environmental Sciences

Palladium nanoparticles exposure: Evaluation of permeation through damaged and intact human skin

Francesca Larese Filon et al.

ENVIRONMENTAL POLLUTION (2016)

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Editorial Material Immunology

Immunotoxicological impact of occupational and environmental nanoparticles exposure: The influence of physical, chemical, and combined characteristics of the particles

Paola Pedata et al.

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (2016)

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Article Chemistry, Multidisciplinary

Effects of thermoresponsivity and softness on skin penetration and cellular uptake of polyglycerol-based nanogels

Fiorenza Rancan et al.

JOURNAL OF CONTROLLED RELEASE (2016)

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Article Multidisciplinary Sciences

Cobalt oxide nanoparticles can enter inside the cells by crossing plasma membranes

Elena Bossi et al.

SCIENTIFIC REPORTS (2016)

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Review Pediatrics

Air pollution and allergic diseases

Eric B. Brandt et al.

CURRENT OPINION IN PEDIATRICS (2015)

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Article Allergy

Exposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility

Eric B. Brandt et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2015)

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Article Chemistry, Multidisciplinary

Interactions of Skin with Gold Nanoparticles of Different Surface Charge, Shape, and Functionality

Rute Fernandes et al.

SMALL (2015)

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Article Multidisciplinary Sciences

Shape-Dependent Skin Penetration of Silver Nanoparticles: Does It Really Matter?

Yu Kyung Tak et al.

SCIENTIFIC REPORTS (2015)

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Article Biochemistry & Molecular Biology

Acute exposure to silica nanoparticles aggravate airway inflammation: different effects according to surface characteristics

Hye Jung Park et al.

EXPERIMENTAL AND MOLECULAR MEDICINE (2015)

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Article Public, Environmental & Occupational Health

Occupational Handling of Nickel Nanoparticles: A Case Report

W. Shane Journeay et al.

AMERICAN JOURNAL OF INDUSTRIAL MEDICINE (2014)

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Article Environmental Sciences

Sneezing and Allergic Dermatitis were Increased in Engineered Nanomaterial Handling Workers

Hui-Yi Liao et al.

INDUSTRIAL HEALTH (2014)

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Article Biochemistry & Molecular Biology

Effect of Nanoparticles Exposure on Fractional Exhaled Nitric Oxide (FENO) in Workers Exposed to Nanomaterials

Wei-Te Wu et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2014)

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Article Allergy

Environmental effects on immune responses in patients with atopy and asthma

Rachel L. Miller et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)

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Article Nanoscience & Nanotechnology

Interaction with culture medium components, cellular uptake and intracellular distribution of cobalt nanoparticles, microparticles and ions in Balb/3T3 mouse fibroblasts

Enrico Sabbioni et al.

NANOTOXICOLOGY (2014)

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Article Nanoscience & Nanotechnology

Cytotoxicity and morphological transforming potential of cobalt nanoparticles, microparticles and ions in Balb/3T3 mouse fibroblasts: an in vitro model

Enrico Sabbioni et al.

NANOTOXICOLOGY (2014)

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Article Immunology

Palladium Nanoparticles Induce Disturbances in Cell Cycle Entry and Progression of Peripheral Blood Mononuclear Cells: Paramount Role of Ions

Claudia Petrarca et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2014)

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Article Nanoscience & Nanotechnology

Nanoparticles from photocopiers induce oxidative stress and upper respiratory tract inflammation in healthy volunteers

Madhu Khatri et al.

NANOTOXICOLOGY (2013)

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Article Toxicology

Immunomodulatory properties of multi-walled carbon nanotubes in peripheral blood mononuclear cells from healthy subjects and allergic patients

Gilles Laverny et al.

TOXICOLOGY LETTERS (2013)

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Article Biochemistry & Molecular Biology

Amorphous silica nanoparticles enhance cross-presentation in murine dendritic cells

Toshiro Hirai et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2012)

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Article Immunology

Size-Dependent Attenuation of TLR9 Signaling by Gold Nanoparticles in Macrophages

Chiau-Yuang Tsai et al.

JOURNAL OF IMMUNOLOGY (2012)

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Article Public, Environmental & Occupational Health

Effects of Palladium Nanoparticles on the Cytokine Release from Peripheral Blood Mononuclear Cells of Palladium-Sensitized Women

Marcella Reale et al.

JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE (2011)

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Article Environmental Sciences

Repeated-dose toxicity and inflammatory responses in mice by oral administration of silver nanoparticles

Eun-Jung Park et al.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2010)

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Article Immunology

SIZE EFFECTS OF POLYSTYRENE NANOPARTICLES ON ATOPIC DERMATITIS-LIKE SKIN LESIONS IN NC/NGA MICE

R. Yanagisawa et al.

INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY (2010)

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Article Medicine, Research & Experimental

Titanium Dioxide Nanoparticles Aggravate Atopic Dermatitis-Like Skin Lesions in NC/Nga Mice

Rie Yanagisawa et al.

EXPERIMENTAL BIOLOGY AND MEDICINE (2009)

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Editorial Material Allergy

A case of toxic epidermal necrolysis-like dermatitis evolving from contact dermatitis of the hands associated with exposure to dendrimers

T. Toyama et al.

CONTACT DERMATITIS (2008)

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