Therapies for Olfactory Dysfunction - an Update

Purpose of Review Olfactory dysfunction is a prevalent condition affecting 5-15% of the general population, with significant impact on quality of life. This review summarizes the most recent and relevant literature in the treatment of olfactory dysfunction. ecent Findings Current evidence supports the short-term use of topical corticosteroids and systemic therapy. These treatments may occur in conjunction with olfactory training, which is well supported by the literature. While there are several additional treatments currently under investigation, meaningful conclusions are not yet able to be made regarding their efficacy. Summary: The treatment of olfactory dysfunction is targeted at the suspected etiology when possible. After normal aging, chronic rhinosinusitis, post-infectious sequelae including as a result SARS-CoV-2 infection (COVID-19), and head trauma are the most common causes. Current evidence supports the short-term use of topical corticosteroids and systemic therapy. Several additional treatments are under investigation but recommendations for their use cannot currently be made.

Automated summary

The purpose of this review is to summarize the latest literature on the treatment of olfactory dysfunction, a common condition affecting 5-15% of the population. Current evidence suggests that short-term use of topical corticosteroids and systemic therapy, combined with olfactory training, can be effective in treating olfactory dysfunction. However, further research is needed to draw meaningful conclusions on the efficacy of other treatments under investigation.