期刊
COLORECTAL DISEASE
卷 24, 期 3, 页码 284-291出版社
WILEY
DOI: 10.1111/codi.15977
关键词
abdominoperineal resection; rectal cancer; washout
资金
- Stig and Ragna Gorthon Foundation
The study found no significant differences in terms of local recurrence, distant metastasis, and overall recurrence between the rectal washout group and the no rectal washout group in abdominoperineal resection for rectal cancer. Additionally, rectal washout did not significantly affect the oncological outcome.
Aim Intraoperative rectal washout is performed to eliminate exfoliated intraluminal cancer cells and thereby decrease the risk of local recurrence. Rectal washout in abdominoperineal resection has not been studied. The aim of this study was to assess the oncological outcome after rectal washout in abdominoperineal resection for rectal cancer and to find evidence as to whether rectal washout should be performed or not. Method Data for all patients registered in the Swedish Colorectal Cancer Registry who underwent elective surgery with abdominoperineal resection for rectal cancer (TNM Stages I-III) between 2007 and 2013 were analysed using multivariable analysis. Results No significant differences were shown between the rectal washout group and the no rectal washout group for local recurrence [10/265 (3.8%) vs. 87/2160 (4.0%), p = 0.84], distant metastasis [51/265 (19.2%) vs. 476/2160 (22.0%), p = 0.29] or overall recurrence [53/265 (20.0%) vs. 505/2160 (23.4%), p = 0.21]. In multivariable analysis, rectal washout did not significantly affect the oncological outcome in terms of local recurrence, distant metastasis, overall recurrence or 5-year overall or relative survival. Conclusion Our results do not support routine rectal washout during abdominoperineal resection in order to improve the oncological outcome.
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