4.1 Article

Robotic Donor Hysterectomy Results in Technical Success and Live Births After Uterus Transplantation: Subanalysis Within the Dallas Uterus Transplant Study (DUETS) Clinical Trial

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CLINICAL OBSTETRICS AND GYNECOLOGY
卷 65, 期 1, 页码 59-67

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/GRF.0000000000000678

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living donor; minimally invasive surgery; robotic hysterectomy; uterus transplantation

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This study demonstrates the feasibility and reproducible success of using uterine grafts from living donors procured by robotic-assisted donor hysterectomies with transvaginal extraction. The recipients had shorter surgical time, less estimated blood loss, and good graft viability, resulting in a high live birth rate.
Minimally invasive procurement of uterine grafts for transplantation can decrease living donor recovery time. We examined recipient outcomes for grafts procured by robotic-assisted donor hysterectomies with transvaginal extraction in the Dallas UtErus Transplant Study (DUETS). All 5 grafts were successfully transplanted. Recipients had a median 4.5-hour surgical time, 0.25 L estimated blood loss, and 4-day hospital stay. Four recipients had grade III surgical complications and three had acute cellular rejection. At 18 months, graft viability was 100%, with an 80% live birth rate. This report demonstrates the feasibility and reproducible success of using uterus grafts from living donors who underwent robotic-assisted donor hysterectomy.

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