4.4 Article

Lipoid Pneumonia After Pembrolizumab Treatment for Advanced Non-Small-Cell Lung Cancer

期刊

CLINICAL LUNG CANCER
卷 23, 期 2, 页码 E116-E117

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CIG MEDIA GROUP, LP
DOI: 10.1016/j.cllc.2021.12.003

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Immune checkpoint inhibitors; Immune-related pneumonitis; Interstitial lung disease; Lipid-laden macrophage; Respiratory failure

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Diagnosing newly emerged abnormal lung shadows during treatment with immune checkpoint inhibitors can be challenging. Clinicians should be aware of this rare but severe phenomenon in patients undergoing immune checkpoint inhibitor therapy.
It is often challenging to diagnose newly emerged abnormal lung shadows during treatment with immune checkpoint inhibitors. We report an autopsy case of a patient who developed lipoid pneumonia after a single dose of pembrolizumab. Clinicians will bear in mind this rare but severe phenomenon in patients undergoing immune checkpoint inhibitor therapy. (C) 2021 Elsevier Inc. All rights reserved.

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