Multisystem Inflammatory Syndrome in Children-United States, February 2020-July 2021

Article Emergency Medicine

Identifying pediatric patients with multisystem inflammatory syndrome in children presenting to a pediatric emergency department

Jaclyn N. Kline et al.

Summary: In this study, CRP elevation and lymphopenia were found to have high sensitivity and specificity for identifying children with Multisystem Inflammatory Syndrome in Children (MIS-C).

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2022)

添加到收藏夹

Article Medicine, General & Internal

Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19

Leora R. Feldstein et al.

Summary: Comparing the clinical characteristics and outcomes of patients with MIS-C and COVID-19 can help distinguish between the two conditions and improve health outcomes. Patterns of clinical presentation and organ system involvement were identified in this case series, providing valuable information for differentiation of MIS-C and COVID-19.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Racial and Ethnic Disparities in COVID-19 Incidence by Age, Sex, and Period Among Persons Aged

Miriam E. Van Dyke et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

添加到收藏夹

Article Pediatrics

Factors linked to severe outcomes in multisystem inflammatory syndrome in children (MIS-C) in the USA a retrospective surveillance study

Joseph Y. Abrams et al.

Summary: Factors such as age, race, clinical symptoms, and laboratory markers were found to be associated with severe outcomes in patients with MIS-C. These findings highlight the importance of early recognition and prompt management for patients with MIS-C.

LANCET CHILD & ADOLESCENT HEALTH (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

The Advisory Committee on Immunization Practices’ Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine in Children Aged 5–11 Years — United States, November 2021

Kate R. Woodworth et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

添加到收藏夹

Article Pediatrics

Trends in Geographic and Temporal Distribution of US Children With Multisystem Inflammatory Syndrome During the COVID-19 Pandemic

Ermias D. Belay et al.

Summary: This study conducted a cross-sectional analysis of a large cohort of patients with MIS-C in the United States, identifying 2 peaks that followed COVID-19 peaks by 2 to 5 weeks. The geographic and temporal association of MIS-C with the COVID-19 pandemic suggested that MIS-C resulted from delayed immunologic responses to SARS-CoV-2 infection. Clinical manifestations varied by age and presence or absence of preceding COVID-19.

JAMA PEDIATRICS (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Trends in Racial and Ethnic Disparities in COVID-19 Hospitalizations, by Region - United States, March-December 2020

Sebastian D. Romano et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

The Advisory Committee on Immunization Practices' Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine in Adolescents Aged 12-15 Years - United States, May 2021

Megan Wallace et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

添加到收藏夹

Article Medicine, General & Internal

Multisystem Inflammatory Syndrome in Children - Initial Therapy and Outcomes

Mary Beth F. Son et al.

Summary: Initial treatment with IVIG plus glucocorticoids was associated with a lower risk of cardiovascular dysfunction compared to IVIG alone in children with MIS-C.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Guidance for Implementing COVID-19 Prevention Strategies in the Context of Varying Community Transmission Levels and Vaccination Coverage

Athalia Christie et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Alternative Methods for Grouping Race and Ethnicity to Monitor COVID-19 Outcomes and Vaccination Coverage

Paula Yoon et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

添加到收藏夹

Article Public, Environmental & Occupational Health

Trends in COVID-19 Cases, Emergency Department Visits, and Hospital Admissions Among Children and Adolescents Aged 0–17 Years — United States, August 2020–August 2021

David A. Siegel et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

添加到收藏夹

Article Immunology

Demographic and Clinical Factors Associated With Death Among Persons <21 Years Old With Multisystem Inflammatory Syndrome in Children-United States, February 2020-March 2021

Anna Bowen et al.

Summary: MIS-C primarily affects racial/ethnic minority groups, with increased risk of death for those aged 16-20 or with comorbidities. Targeting COVID-19 prevention among these groups and their caregivers may reduce MIS-C-related deaths.

OPEN FORUM INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Medicine, General & Internal

Incidence of Multisystem Inflammatory Syndrome in Children Among US Persons Infected With SARS-CoV-2

Amanda B. Payne et al.

Summary: In this study, it was found that Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare complication associated with SARS-CoV-2 infection, with higher incidence rates among Black, Hispanic or Latino, and Asian or Pacific Islander individuals. Further research is needed to explore the variations by race/ethnicity and age group.

JAMA NETWORK OPEN (2021)

添加到收藏夹

Article Infectious Diseases

Retropharyngeal Edema and Neck Pain in Multisystem Inflammatory Syndrome in Children (MIS-c)

Elan Jenkins et al.

Summary: Neck inflammation symptoms are common in patients with multisystem inflammatory syndrome in children (MIS-c), with retropharyngeal edema being a documented issue in at least 9 cases.

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY (2021)

添加到收藏夹

Article Medicine, General & Internal

Data-driven clustering identifies features distinguishing multisystem inflammatory syndrome from acute COVID-19 in children and adolescents

Alon Geva et al.

Summary: Through unsupervised clustering analysis, researchers identified features with a high likelihood of having MIS-C and also identified a group of patients more likely to have acute severe COVID-19 pulmonary disease. The results of the study help refine the diagnosis of MIS-C.

ECLINICALMEDICINE (2021)

添加到收藏夹

Article Medicine, General & Internal