4.7 Article

Severe Acute Respiratory Syndrome Coronavirus 2 Reinfection Associates With Unstable Housing and Occurs in the Presence of Antibodies

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Immunology

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Sequence Characteristics of Coronavirus Disease 2019 (COVID-19) Persistence and Reinfection

Manish C. Choudhary et al.

Summary: This study investigated reinfection and persistent infection of SARS-CoV-2, finding that reinfecting viral genomes largely resemble contemporaneous circulating sequences in a geographic region, while persistent COVID-19 is mainly described in immunosuppressed individuals and is associated with accelerated viral evolution.

CLINICAL INFECTIOUS DISEASES (2022)

Article Immunology

Risk of Reinfection After Seroconversion to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): A Population-based Propensity-score Matched Cohort Study

Antonio Leidi et al.

Summary: This study found that seroconversion after SARS-CoV-2 infection provides protection against reinfection lasting at least 8 months. These findings could aid global health authorities in prioritizing vaccine allocation.

CLINICAL INFECTIOUS DISEASES (2022)

Article Immunology

Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 Replication in an Immunocompromised Patient

Ji Hoon Baang et al.

Summary: This case illustrates challenges in managing immunocompromised hosts with chronic COVID-19, who may act as persistent shedders and sources of transmission. The patient's lack of seroconversion and prolonged course highlight the importance of humoral immunity in resolving viral infections.

JOURNAL OF INFECTIOUS DISEASES (2021)

Article Infectious Diseases

Genomic evidence for reinfection with SARS-CoV-2: a case study

Richard L. Tillett et al.

Summary: A man was infected with SARS-CoV-2 twice with genetically different virus variants, the second infection being more severe. The study suggests that previous exposure to SARS-CoV-2 may not guarantee immunity, and all individuals should take precautions to avoid infection. This has implications for vaccine development and application.

LANCET INFECTIOUS DISEASES (2021)

Review Biochemistry & Molecular Biology

Adaptive immunity to SARS-CoV-2 and COVID-19

Alessandro Sette et al.

Summary: The adaptive immune system, consisting of B cells, CD4(+) T cells, and CD8(+) T cells, plays varying roles in different viral infections and vaccines. Studies are showing that CD4(+) T cells, CD8(+) T cells, and neutralizing antibodies all play a part in controlling SARS-CoV-2 in COVID-19 cases, emphasizing the importance of understanding adaptive immunity in combating the disease.
Article Immunology

Symptomatic Severe Acute Respiratory Syndrome Coronavirus 2 Reinfection of a Healthcare Worker in a Belgian Nosocomial Outbreak Despite Primary Neutralizing Antibody Response

Philippe Selhorst et al.

Summary: This study observed a case of SARS-CoV-2 reinfection in a healthy healthcare worker, with symptomatic reinfection occurring 185 days after the initial infection. Despite the development of an effective humoral immune response following the primary infection, the viral genomes of the reinfection were different from the initial infection.

CLINICAL INFECTIOUS DISEASES (2021)

Article Medicine, General & Internal

Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers

S. F. Lumley et al.

Summary: In a longitudinal study of seropositive and seronegative health care workers undergoing asymptomatic and symptomatic SARS-CoV-2 testing, the presence of anti-spike or anti-nucleocapsid IgG antibodies was associated with a substantially reduced risk of SARS-CoV-2 reinfection in the ensuing 6 months.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Editorial Material Health Care Sciences & Services

Addressing the COVID-19 Pandemic Among Persons Experiencing Homelessness: Steps to Protect a Vulnerable Population

Joshua A. Barocas et al.

JOURNAL OF GENERAL INTERNAL MEDICINE (2021)

Article Immunology

Long-Term Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectiousness Among Three Immunocompromised Patients: From Prolonged Viral Shedding to SARS-CoV-2 Superinfection

Hassan Tarhini et al.

Summary: This study describes the clinical evolutions and viral mutations of 3 deeply immunocompromised patients, revealing prolonged infectious viral shedding in some cases. Understanding the mechanisms and frequency of prolonged infectiousness is crucial for optimizing isolation policies.

JOURNAL OF INFECTIOUS DISEASES (2021)

Article Multidisciplinary Sciences

SARS-CoV-2 evolution during treatment of chronic infection

Steven A. Kemp et al.

Summary: Chronic infection with SARS-CoV-2 can lead to viral evolution and increased resistance to neutralizing antibodies in immunosuppressed individuals treated with convalescent plasma. During convalescent plasma therapy, there were significant shifts in the viral population structure and sensitivity, suggesting strong selection pressure on the virus during treatment.

NATURE (2021)

Article Immunology

Reinfection Rates Among Patients Who Previously Tested Positive for Coronavirus Disease 2019: A Retrospective Cohort Study

Megan M. Sheehan et al.

Summary: The study found that prior infection in patients with COVID-19 provided a high level of protection against reinfection and symptomatic disease, with this protection increasing over time. This suggests that viral shedding or ongoing immune response may persist beyond 90 days, and may not necessarily represent true reinfection.

CLINICAL INFECTIOUS DISEASES (2021)

Article Medicine, General & Internal

Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study

Christian Holm Hansen et al.

Summary: The study investigated the protection against SARS-CoV-2 reinfection, with results showing an 80.5% protection rate for individuals previously infected. Even in the population aged 65 years and older, the protection rate against reinfection reached 47.1%, with no significant differences observed by gender or time since infection.

LANCET (2021)

Article Immunology

Novel ELISA Protocol Links Pre-Existing SARS-CoV-2 Reactive Antibodies With Endemic Coronavirus Immunity and Age and Reveals Improved Serologic Identification of Acute COVID-19 via Multi-Parameter Detection

Rachel R. Yuen et al.

Summary: This study presents a new ELISA protocol for the sensitive measurement of SARS-CoV-2 specific antibodies, allowing for higher resolution detection of IgM, IgG, and IgA levels. The method showed promising implications for improved serologic identification of SARS-CoV-2 infection and offered new insights into the dynamics of virus transmission and pathogenesis.

FRONTIERS IN IMMUNOLOGY (2021)

Article Multidisciplinary Sciences

Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection

Zijun Wang et al.

Summary: Despite challenges posed by COVID-19 variants, convalescent individuals receiving mRNA vaccines exhibit robust and long-lasting immune responses against circulating SARS-CoV-2 variants, providing hope for effective control of the pandemic.

NATURE (2021)

Article Multidisciplinary Sciences

Seroprevalence of SARS-CoV-2 antibodies among homeless people living rough, in shelters and squats: A large population-based study in France

Sandrine Loubiere et al.

Summary: This study assessed the seroprevalence of SARS-CoV-2 infection among homeless individuals in Marseille, France, and found that overcrowded or inadequate accommodations increase the risk of infection. Regular screening among the homeless is necessary to prevent clustering and essential resources should be provided to keep this population healthy, as they have cumulative risk factors for SARS-CoV-2 infection.

PLOS ONE (2021)

Letter Medicine, General & Internal

Assessment of SARS-CoV-2 Reinfection 1 Year After Primary Infection in a Population in Lombardy, Italy

Jose Vitale et al.

Summary: This cohort study investigates the rate of SARS-CoV-2 reinfection among individuals in Lombardy, Italy, who had previously recovered from COVID-19.

JAMA INTERNAL MEDICINE (2021)

Article Public, Environmental & Occupational Health

Reduced Risk of Reinfection with SARS-CoV-2 After COVID-19 Vaccination — Kentucky, May–June 2021

Alyson M. Cavanaugh et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2021)

Article Medicine, General & Internal

SARS-CoV-2 antibody-positivity protects against reinfection for at least seven months with 95% efficacy

Laith J. Abu-Raddad et al.

Summary: The study shows that reinfection is rare in Qatar's young and international population, with natural infection providing strong protection against reinfection with an estimated efficacy of around 95% for at least seven months. Reinfections are often less severe than primary infections.

ECLINICALMEDICINE (2021)

Letter Medicine, General & Internal

Prevalence of SARS-CoV-2 Infection in Residents of a Large Homeless Shelter in Boston

Travis P. Baggett et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Public, Environmental & Occupational Health

Assessment of SARS-CoV-2 Infection Prevalence in Homeless Shelters - Four US Cities, March 27-April 15, 2020

Emily Mosites et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

Article Biochemistry & Molecular Biology

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections

Quan-Xin Long et al.

NATURE MEDICINE (2020)

Article Biochemical Research Methods

Quantification of SARS-CoV-2 neutralizing antibody by a pseudotyped virus-based assay

Jianhui Nie et al.

NATURE PROTOCOLS (2020)

Letter Medicine, General & Internal

Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host

Bina Choi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Letter Infectious Diseases

A case of SARS-CoV-2 reinfection in Ecuador

Belen Prado-Vivar et al.

LANCET INFECTIOUS DISEASES (2020)

Article Biochemical Research Methods

Fast gapped-read alignment with Bowtie 2

Ben Langmead et al.

NATURE METHODS (2012)