☆ 4.7 Review

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Dose, Infection, and Disease Outcomes for Coronavirus Disease 2019 (COVID-19): A Review

CLINICAL INFECTIOUS DISEASES (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Review Immunology

A systematic review of asymptomatic infections with COVID-19

Zhiru Gao et al.

Summary: Since the outbreak of COVID-19 at the end of December 2019, it has caused significant harm and challenges to over 200 countries and regions worldwide. Many patients with COVID-19 are asymptomatic or have only mild symptoms, yet they can still spread the virus, making screening for asymptomatic infections difficult and complicating national prevention and control efforts.

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION (2021)

添加到收藏夹

Review Virology

Proportion of asymptomatic coronavirus disease 2019: A systematic review and meta-analysis

Jingjing He et al.

Summary: Approximately 15.6% of confirmed COVID-19 patients are asymptomatic. Nearly half of the patients with no symptoms at detection time will develop symptoms later. Children are likely to have a higher proportion of asymptomatic infection than adults. Asymptomatic COVID-19 patients could have abnormal laboratory and radiational manifestations, which can be used as screening strategies to identify asymptomatic infection.

JOURNAL OF MEDICAL VIROLOGY (2021)

添加到收藏夹

Review Public, Environmental & Occupational Health

COVID-19 in Health-Care Workers: A Living Systematic Review and Meta-Analysis of Prevalence, Risk Factors, Clinical Characteristics, and Outcomes

Sergio Alejandro Gomez-Ochoa et al.

Summary: Health-care workers have an 11% prevalence of SARS-CoV-2 infection, with nurses being the most affected personnel, mainly working in hospital nonemergency wards. 40% of HCWs infected with COVID-19 were asymptomatic at the time of diagnosis, while 5% developed severe complications and 0.5% died.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2021)

添加到收藏夹

Article Immunology

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics Should Inform Policy

Muge Cevik et al.

Summary: Understanding how the virus is transmitted is crucial in identifying high-risk environments and activities for effective preventative measures implementation. Contact tracing and household studies provide robust evidence about transmission parameters. Transmission dynamics should guide policy decisions to target interventions to settings, activities, and socioeconomic factors with the highest risks of transmission.

CLINICAL INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Spike mutation D614G alters SARS-CoV-2 fitness

Jessica A. Plante et al.

Summary: The D614G substitution in the SARS-CoV-2 spike protein enhances viral replication and infectivity in human lung epithelial cells, primary airway tissues, and hamsters. This variant may increase transmission in the upper respiratory tract and doesn't seem to significantly reduce vaccine efficacy. Further research on therapeutic antibodies targeting the circulating G614 virus is recommended.

NATURE (2021)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 6: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

Erik Volz et al.

Summary: The study suggests a positive selection for the SARS-CoV-2 spike protein variant D614G in the UK, but no evidence of differences in COVID-19 mortality or clinical severity in patients infected with this variant. 614G is associated with higher viral load and younger age of patients compared to 614D.

CELL (2021)

添加到收藏夹

Editorial Material Medicine, General & Internal

Genetic Variants of SARS-CoV-2-What Do They Mean?

Adam S. Lauring et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

添加到收藏夹

Article Immunology

Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo

Alexandra Schafer et al.

Summary: The study shows that combined use of hu-mAbs is effective for prevention and therapy of SARS-CoV-2 infection, but in vivo protection is influenced by intact effector function.

JOURNAL OF EXPERIMENTAL MEDICINE (2021)

添加到收藏夹

News Item Medicine, General & Internal

Covid-19: New UK variant may be linked to increased death rate, early data indicate

Gareth Iacobucci

BMJ-BRITISH MEDICAL JOURNAL (2021)

添加到收藏夹

Article Microbiology

K18-hACE2 mice develop respiratory disease resembling severe COVID-19

Claude Kwe Yinda et al.

Summary: The study demonstrates that humanized transgenic mice developed dose-dependent disease when inoculated with SARS-CoV-2, showing upper and lower respiratory tract infection with viral replication also in the brain. The pathological and immunological manifestations observed in these mice resemble human COVID-19, suggesting the model's usefulness in elucidating COVID-19 pathogenesis and testing countermeasures.

PLOS PATHOGENS (2021)

添加到收藏夹

Article Pathology

Acute Respiratory Distress in Aged, SARS-CoV-2-Infected African Green Monkeys but Not Rhesus Macaques

Robert V. Blair et al.

Summary: This study reported two cases of ARDS in AGMs infected with SARS-CoV-2, as well as a comparatively mild COVID-19 phenotype in two surviving AGMs and four infected RMs. The results suggest that aged AGMs may be useful for modeling severe disease manifestations related to COVID-19.

AMERICAN JOURNAL OF PATHOLOGY (2021)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 7: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2021)

添加到收藏夹

Review Infectious Diseases

Serial interval and incubation period of COVID-19: a systematic review and meta-analysis

Muluneh Alene et al.

Summary: This study aimed to determine the overall average serial interval and incubation period of COVID-19 by combining findings of existing studies. The weighted pooled mean serial interval of COVID-19 was found to be 5.2 days and the mean incubation period was 6.5 days. The study suggests that presymptomatic transmission may account for a significant number of COVID-19 cases, as the average serial interval is shorter than the average incubation period.

BMC INFECTIOUS DISEASES (2021)

添加到收藏夹

Editorial Material Medicine, General & Internal

SARS-CoV-2 Variants of Concern in the United States-Challenges and Opportunities

Rochelle P. Walensky et al.

Summary: The Viewpoint discusses the measures taken by federal agencies to rapidly characterize emerging coronavirus variants and monitor their implications for national pandemic response and control. This includes assessment of the ongoing effectiveness of current diagnostics, therapeutics, and vaccines.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

添加到收藏夹

Review Public, Environmental & Occupational Health

Review Seroprevalence of SARS-CoV-2 antibodies and associated factors in healthcare workers: a systematic review and meta-analysis

P. Galanis et al.

Summary: The seroprevalence of SARS-CoV-2 antibodies among HCWs is relatively high and influenced by factors such as gender, race, work environment, and protective measures.

JOURNAL OF HOSPITAL INFECTION (2021)

添加到收藏夹

Article Infectious Diseases

Transmission of COVID-19 in 282 clusters in Catalonia, Spain: a cohort study

Michael Marks et al.

Summary: The viral load of index cases is a key driver of SARS-CoV-2 transmission, while the viral load of contacts at baseline is strongly associated with the risk of developing symptomatic COVID-19 and shortening the incubation period in a dose-dependent manner.

LANCET INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Attributes and predictors of long COVID

Carole H. Sudre et al.

Summary: Reports on long-lasting COVID-19 symptoms, known as 'long COVID', are increasing. Analysis of data from over 4,000 COVID-19 cases revealed that long COVID is more common in older individuals, those with higher body mass index, and females. Experiencing more than five symptoms in the first week of illness was associated with long COVID. A simple model showed promise in distinguishing between short and long COVID cases early in the disease.

NATURE MEDICINE (2021)

添加到收藏夹

Article Virology

Diagnostic SARS-CoV-2 Cycle Threshold Value Predicts Disease Severity, Survival, and Six-Month Sequelae in COVID-19 Symptomatic Patients

Mattia Trunfio et al.

Summary: This study found that the SARS-CoV-2 Ct value at diagnosis could predict disease severity, number of symptoms, and six-month sequelae in COVID-19 patients. Early quantification of SARS-CoV-2 may be a useful predictive marker to inform differential strategies of clinical management and resource allocation.

VIRUSES-BASEL (2021)

添加到收藏夹

Article Multidisciplinary Sciences

SARS-CoV and SARS-CoV-2 are transmitted through the air between ferrets over more than one meter distance

Jasmin S. Kutter et al.

Summary: The study shows that SARS-CoV and SARS-CoV-2 can be transmitted through the air over more than a meter distance in ferrets, indicating that ferrets may be a sensitive model to study interventions aimed at preventing virus transmission.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Medicine, General & Internal

Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study

Robert Challen et al.

Summary: The study found that the mortality hazard ratio associated with infection with VOC-202012/1 compared with previously circulating variants was 1.64, indicating an increase in deaths from 2.5 to 4.1 per 1000 detected cases in comparatively low risk group of covid-19 patients in the community. This suggests that infection with VOC-202012/1 may lead to substantial additional mortality compared with previously circulating variants, impacting healthcare capacity planning and control policies.

BMJ-BRITISH MEDICAL JOURNAL (2021)

添加到收藏夹

Review Multidisciplinary Sciences

Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans

P. J. Klasse et al.

Summary: This article summarizes the progress of multiple preventive vaccines being developed to counter the COVID-19 pandemic, including results from animal and human trials as well as challenge experiments. The focus is on comparing the immunogenicity performance of the vaccines and summarizing the press releases on vaccine efficacy trials.

SCIENCE ADVANCES (2021)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 8: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2021)

添加到收藏夹

Article Infectious Diseases

Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England, 16 November to 5 February

Daniel J. Grint et al.

Summary: The SARS-CoV-2 B.1.1.7 VOC is spreading across Europe and poses a higher risk of death compared to non-VOC cases, with increased mortality in older individuals and those with comorbidities. This variant has the potential to spread faster and cause higher mortality than previous strains.

EUROSURVEILLANCE (2021)

添加到收藏夹

Review Medicine, General & Internal

Frequency, signs and symptoms, and criteria adopted for long COVID-19: A systematic review

Ana Luiza Cabrera Martimbianco et al.

Summary: This systematic review revealed that the frequency of long COVID-19 can reach up to 80%, with chest pain, fatigue, dyspnea, and cough being the most prevalent clinical manifestations. Associated risk factors include old age, female sex, severe clinical status, multiple comorbidities, hospital admission, and oxygen supplementation during the acute phase.

INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2021)

添加到收藏夹

Article Infectious Diseases

Genomic characteristics and clinical effect of the emergent SARS-CoV-2 B.1.1.7 lineage in London, UK: a whole-genome sequencing and hospital-based cohort study

Dan Frampton et al.

Summary: This study describes the emergence of the B.1.1.7 variant of concern, its virological characteristics, and clinical severity in patients. Increased viral load was found in B.1.1.7 infection, but no association with severe disease was identified in the hospitalized cohort.

LANCET INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7

Nicholas G. Davies et al.

Summary: Studies have shown that the SARS-CoV-2 B.1.1.7 lineage is more transmissible and may cause more severe illness compared to pre-existing variants.

NATURE (2021)

添加到收藏夹

Review Microbiology

Transmissibility and transmission of respiratory viruses

Nancy H. L. Leung

Summary: Respiratory virus infections cause a significant global health problem, with different viruses varying in transmission modes and transmissibility. Understanding the relative contributions of different transmission modes is crucial for guiding the effectiveness of non-pharmaceutical interventions.

NATURE REVIEWS MICROBIOLOGY (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil

Nuno R. Faria et al.

Summary: A new variant of concern, P.1, with 17 mutations including three spike protein mutations associated with increased binding to human ACE2 receptors, emerged in Manaus, Brazil between November 2020 and January 2021. Molecular analysis suggests P.1 may be 1.7- to 2.4-fold more transmissible and that previous infection may provide 54 to 79% protection against P.1 infection compared to other lineages. Enhanced global genomic surveillance of such variants is crucial for pandemic response.

SCIENCE (2021)

添加到收藏夹

Article Cell Biology

The neutralizing antibody, LY-CoV555, protects against SARS-CoV-2 infection in nonhuman primates

Bryan E. Jones et al.

Summary: LY-CoV555 is a novel neutralizing antibody derived from a convalescent patient with COVID-19, showing high affinity binding, potent inhibition of ACE2 binding, and strong neutralizing activity. This antibody has entered clinical trials and is being evaluated for various COVID-19 prevention and treatment indications.

SCIENCE TRANSLATIONAL MEDICINE (2021)

添加到收藏夹

Review Medicine, General & Internal

Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge

Martin S. Winkler et al.

Summary: Animal models have played a crucial role in medical research, especially in studying the novel coronavirus. Apart from clinical studies, these models have provided significant support for COVID-19 drug and vaccine development. During pandemics, optimizing the synergy between preclinical and clinical domains is essential for efficient resource utilization.

EBIOMEDICINE (2021)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 9: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2021)

添加到收藏夹

Review Infectious Diseases

COVID-19 false dichotomies and a comprehensive review of the evidence regarding public health, COVID-19 symptomatology, SARS-CoV-2 transmission, mask wearing, and reinfection

Kevin Escandon et al.

Summary: This article discusses the false dichotomies surrounding the COVID-19 pandemic, emphasizing the need for a nuanced understanding of science and caution against extreme messaging.

BMC INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies

Dapeng Li et al.

Summary: Research has shown that some SARS-CoV-2 neutralizing antibodies can enhance virus infection in vitro, but in monkeys and mice, these antibodies can still protect against SARS-CoV-2. However, out of 46 monkeys infused with enhancing antibodies, three showed higher lung inflammation scores compared to controls.

CELL (2021)

添加到收藏夹

Article Microbiology

An AAV-based, room-temperature-stable, single-dose COVID-19 vaccine provides durable immunogenicity and protection in non-human primates

Nerea Zabaleta et al.

Summary: The AAVCOVID-1 vaccine candidate demonstrates potent immunogenicity in animal experiments and provides complete protection against SARS-CoV-2 in macaques. It has sustained neutralizing antibody responses and functional memory T cell responses, with no cross-reactivity to common AAVs used in gene therapy.

CELL HOST & MICROBE (2021)

添加到收藏夹

Letter Medicine, General & Internal

SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness

Aziz Sheikh et al.

LANCET (2021)

添加到收藏夹

Article Infectious Diseases

Mortality and critical care unit admission associated with the SARS-CoV-2 lineage B.1.1.7 in England: an observational cohort study

Martina Patone et al.

Summary: This study analyzed the clinical outcomes of patients infected with the new SARS-CoV-2 lineage B.1.1.7 compared to non-B.1.1.7 infections, finding that patients with B.1.1.7 were more likely to be admitted to critical care units and die within 28 days. However, for patients receiving critical care, mortality seemed to be independent of the virus strain.

LANCET INFECTIOUS DISEASES (2021)

添加到收藏夹

Article Multidisciplinary Sciences

SARS-CoV-2 disease severity and transmission efficiency is increased for airborne compared to fomite exposure in Syrian hamsters

Julia R. Port et al.

Summary: Port and Yinda et al. directly compared the relative contribution of contact, fomite, and airborne transmission routes of SARS-CoV-2 in Syrian hamsters and found that different routes of exposure lead to distinct disease manifestations. Infection through intranasal and aerosol exposure caused severe respiratory pathology, while fomite exposure resulted in milder disease characterized by an anti-inflammatory immune state and delayed shedding pattern.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Article Multidisciplinary Sciences

Sex and age bias viral burden and interferon responses during SARS-CoV-2 infection in ferrets

Magen E. Francis et al.

Summary: SARS-CoV-2 infections have a disproportionate impact on males and older individuals, with male ferrets showing prolonged viral replication in the upper respiratory tract post-infection. Female ferrets, especially those aged 1 year, exhibited significant increases in interferon response genes post-infection. These findings suggest that older males may have a role in viral transmission due to delayed antiviral responses.

SCIENTIFIC REPORTS (2021)

添加到收藏夹

Article Cell Biology

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice

David R. Martinez et al.

Summary: Research shows that a combination of two mAbs in clinical trials has strong antiviral effects and therapeutic efficacy against certain variants, while combining RDV and antibodies slightly improves treatment outcomes, supporting the continued use of RDV to treat SARS-CoV-2 infections.

CELL REPORTS (2021)

添加到收藏夹

Review Biology

Diabetes and COVID-19

Zohair Jamil Gazzaz

Summary: Several factors are linked with a higher risk of mortality from COVID-19, including hypertension, diabetes mellitus, etc. Patients with diabetes or hyperglycemia have a higher mortality rate due to compromised immune response. Integrated team approach is needed for the treatment of COVID-19 patients with diabetes.

OPEN LIFE SCIENCES (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Gender associates with both susceptibility to infection and pathogenesis of SARS-CoV-2 in Syrian hamster

Lunzhi Yuan et al.

Summary: Experimental studies on Syrian hamsters infected with SARS-CoV-2 showed that male hamsters had higher viral titers, more severe symptoms, and lung pathogenicity compared to female hamsters, providing evidence that the severity of SARS-CoV-2 infection and COVID-19 outcomes are associated with gender.

SIGNAL TRANSDUCTION AND TARGETED THERAPY (2021)

添加到收藏夹

Review Infectious Diseases

SARS-CoV-2, SARS-CoV, and MERS-CoV viral load dynamics, duration of viral shedding, and infectiousness: a systematic review and meta-analysis

Muge Cevik et al.

Summary: This study aimed to characterize the viral load dynamics, duration of viral shedding, and viable virus shedding of SARS-CoV-2 in various body fluids. The findings suggest that while SARS-CoV-2 RNA shedding can be prolonged in respiratory and stool samples, the duration of viable virus shedding is relatively short-lived.

LANCET MICROBE (2021)

添加到收藏夹

Article Multidisciplinary Sciences

COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice

Jian Zheng et al.

Summary: The COVID-19 pandemic is associated with significant morbidity and mortality. Experimental studies in animals infected with SARS-CoV-2 have revealed severe lung and brain damage, as well as early onset anosmia in mice. Excitingly, infusion of convalescent plasma from recovered patients has shown to protect against lethal disease, though it does not prevent anosmia.

NATURE (2021)

添加到收藏夹

Review Medicine, General & Internal

Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers A Living Rapid Review

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Spike protein recognition of mammalian ACE2 predicts the host range and an optimized ACE2 for SARS-CoV-2 infection

Junwen Luan et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Pathogenesis of SARS-CoV-2 in Transgenic Mice Expressing Human Angiotensin-Converting Enzyme 2

Ren-Di Jiang et al.

CELL (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

Markus Hoffmann et al.

CELL (2020)

添加到收藏夹

Article Microbiology

Infection and Rapid Transmission of SARS-CoV-2 in Ferrets

Young-Il Kim et al.

CELL HOST & MICROBE (2020)

添加到收藏夹

Article Immunology

Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19)

Jasper Fuk-Woo Chan et al.

CLINICAL INFECTIOUS DISEASES (2020)

添加到收藏夹

Review Infectious Diseases

Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis

Jing Yang et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

添加到收藏夹

Review Infectious Diseases

Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis

Zhaohai Zheng et al.

JOURNAL OF INFECTION (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2

Jianzhong Shi et al.

SCIENCE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Pathogenesis and transmission of SARS-CoV-2 in golden hamsters

Sin Fun Sia et al.

NATURE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice

Linlin Bao et al.

NATURE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Temporal dynamics in viral shedding and transmissibility of COVID-19

Xi He et al.

NATURE MEDICINE (2020)

添加到收藏夹

Review Cell Biology

Epidemiological, comorbidity factors with severity and prognosis of COVID-19: a systematic review and meta-analysis

Xiaoyu Fang et al.

AGING-US (2020)

添加到收藏夹

Article Public, Environmental & Occupational Health

Evaluation of K18-hACE2 Mice as a Model of SARS-CoV-2 Infection

Gregory Brett Moreau et al.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2020)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2020)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 2: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2020)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 3: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2020)

添加到收藏夹

Article Environmental Sciences

Aerosol transmission of SARS-CoV-2? Evidence, prevention and control

Song Tang et al.

ENVIRONMENT INTERNATIONAL (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus

Bette Korber et al.

CELL (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

Ahmed O. Hassan et al.

CELL (2020)

添加到收藏夹

Letter Critical Care Medicine

SARS-CoV-2 viral load predicts COVID-19 mortality

Elisabet Pujadas et al.

LANCET RESPIRATORY MEDICINE (2020)

添加到收藏夹

Article Public, Environmental & Occupational Health

Characteristics of Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status - United States, January 22-June 7, 2020

Sascha Ellington et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

添加到收藏夹

Article Public, Environmental & Occupational Health

Hospitalization Rates and Characteristics of Children Aged <18 Years Hospitalized with Laboratory-Confirmed COVID-19-COVID-NET, 14 States, March 1-July 25, 2020

Lindsay Kim et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

添加到收藏夹

Review Emergency Medicine

COVID-19 in health care workers - A systematic review and meta-analysis

Ankit Kumar Sahu et al.

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2020)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 5: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2020)

添加到收藏夹

Letter Medicine, General & Internal

Update Alert 4: Epidemiology of and Risk Factors for Coronavirus Infection in Health Care Workers

Roger Chou et al.

ANNALS OF INTERNAL MEDICINE (2020)

添加到收藏夹

Article Infectious Diseases

A minimal common outcome measure set for COVID-19 clinical research

J. C. Marshall et al.

LANCET INFECTIOUS DISEASES (2020)

添加到收藏夹

Article Oncology

SARS-CoV-2 Viral Load Predicts Mortality in Patients with and without Cancer Who Are Hospitalized with COVID-19

Lars F. Westblade et al.

CANCER CELL (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Hydroxychloroquine use against SARS-CoV-2 infection in non-human primates

Pauline Maisonnasse et al.

NATURE (2020)

添加到收藏夹

Review Endocrinology & Metabolism

Obesity is a risk factor for developing critical condition in COVID-19 patients: A systematic review and meta-analysis

Maria Foldi et al.

OBESITY REVIEWS (2020)

添加到收藏夹

Article Immunology

Recombinant SARS-CoV-2 spike S1-Fc fusion protein induced high levels of neutralizing responses in nonhuman primates

Wenlin Ren et al.

VACCINE (2020)

添加到收藏夹

Article Virology

Age-Dependent Progression of SARS-CoV-2 Infection in Syrian Hamsters

Nikolaus Osterrieder et al.

VIRUSES-BASEL (2020)

添加到收藏夹

Article Multidisciplinary Sciences

SARS-CoV-2 is transmitted via contact and via the air between ferrets

Mathilde Richard et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Review Infectious Diseases

Asymptomatic patients as a source of COVID-19 infections: A systematic review and meta-analysis

Andreas Kronbichler et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

添加到收藏夹

Review Infectious Diseases

The duration of infectiousness of individuals infected with SARS-CoV-2

Kieran A. Walsh et al.

JOURNAL OF INFECTION (2020)

添加到收藏夹

Article Virology

Disruption of Adaptive Immunity Enhances Disease in SARS-CoV-2-Infected Syrian Hamsters

Rebecca L. Brocato et al.

JOURNAL OF VIROLOGY (2020)

添加到收藏夹

Review Immunology

Animal and translational models of SARS-CoV-2 infection and COVID-19

M. D. Johansen et al.

MUCOSAL IMMUNOLOGY (2020)

添加到收藏夹

Article Multidisciplinary Sciences

A mouse-adapted model of SARS-CoV-2 to test COVID-19 countermeasures

Kenneth H. Dinnon et al.

NATURE (2020)

添加到收藏夹

Article Immunology

SARS-CoV-2 infection of human ACE2-transgenic mice causes severe lung inflammation and impaired function

Emma S. Winkler et al.

NATURE IMMUNOLOGY (2020)

添加到收藏夹

Review Physiology

SARS-CoV-2 AND COVID-19: FROM THE BENCH TO THE BEDSIDE

Stefano Romagnoli et al.

PHYSIOLOGICAL REVIEWS (2020)

添加到收藏夹

Review Multidisciplinary Sciences

Association of cardiovascular disease and 10 other pre-existing comorbidities with COVID-19 mortality: A systematic review and meta-analysis

Paddy Ssentongo et al.

PLOS ONE (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in rhesus macaques

Wei Deng et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Review Medicine, General & Internal

Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis

John Allotey et al.

BMJ-BRITISH MEDICAL JOURNAL (2020)

添加到收藏夹

Article Medicine, General & Internal

Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: A living systematic review and meta-analysis

Diana Buitrago-Garcia et al.

PLOS MEDICINE (2020)

添加到收藏夹

Article Microbiology

SARS-CoV-2 infection of African green monkeys results in mild respiratory disease discernible by PET/CT imaging and shedding of infectious virus from both respiratory and gastrointestinal tracts

Amy L. Hartman et al.

PLOS PATHOGENS (2020)

添加到收藏夹

Article Public, Environmental & Occupational Health

Case Series of Multisystem Inflammatory Syndrome in Adults Associated with SARS-CoV-2 Infection - United Kingdom and United States, March-August 2020

Sapna Bamrah Morris et al.

MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT (2020)

添加到收藏夹

Article Medicine, Research & Experimental

Human angiotensin-converting enzyme 2 transgenic mice infected with SARS-CoV-2 develop severe and fatal respiratory disease

Joseph W. Golden et al.

JCI INSIGHT (2020)

添加到收藏夹

Article Multidisciplinary Sciences

Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates

M. D. Fahlberg et al.

NATURE COMMUNICATIONS (2020)

添加到收藏夹

Review Medicine, General & Internal

Household Transmission of SARS-CoV-2 A Systematic Review and Meta-analysis

Zachary J. Madewell et al.

JAMA NETWORK OPEN (2020)

添加到收藏夹

Review Public, Environmental & Occupational Health

Infection and mortality of healthcare workers worldwide from COVID-19: a systematic review

Soham Bandyopadhyay et al.

BMJ GLOBAL HEALTH (2020)

添加到收藏夹

Letter Medicine, General & Internal

Facial Masking for Covid-19

Angela L. Rasmussen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

添加到收藏夹

Article Cell Biology

Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters

Andrew Chak-Yiu Lee et al.

CELL REPORTS MEDICINE (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Age-related rhesus macaque models of COVID-19

Pin Yu et al.

ANIMAL MODELS AND EXPERIMENTAL MEDICINE (2020)

添加到收藏夹

Article Immunology

Defining the Syrian hamster as a highly susceptible preclinical model for SARS-CoV-2 infection

Kyle Rosenke et al.

EMERGING MICROBES & INFECTIONS (2020)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.