期刊
CLINICAL INFECTIOUS DISEASES
卷 75, 期 1, 页码 E916-E919出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/cid/ciab1009
关键词
COVID-19; HIV; immune response; SARS-CoV-2; vaccination
资金
- US National Institute of Allergy and Infectious Diseases (NIAID) [R01AI158013]
- US NIAID [P30AI027763]
Following SARS-CoV-2 mRNA vaccination, people living with HIV had lower neutralizing antibody response and a trend toward lower IgG response, especially among those with lower CD4(+) T-cell counts and who received the BNT162b2 vaccine. Further study is needed to understand the impact of supplemental vaccine doses among PLWH.
Following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccination, people living with human immunodeficiency virus (HIV, PLWH) had lower surrogate virus neutralization test response (P = .03) and a trend toward lower immunoglobulin G (IgG) response (P = .08), particularly among those with lower CD4(+) T-cell counts and who received the BNT162b2 vaccine. Study of the impact of supplemental vaccine doses among PLWH is needed.
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