Commercial immunoassays for detection of anti-SARS-CoV-2 spike and RBD antibodies: urgent call for validation against new and highly mutated variants

Article Multidisciplinary Sciences

SARS-CoV-2 vaccine protection and deaths among US veterans during 2021

Barbara A. Cohn et al.

Summary: This study reports the effectiveness of vaccines against SARS-CoV-2 infection and death in veterans, with a decline in vaccine effectiveness observed for all vaccine types. The decline was greatest for the Janssen vaccine. However, vaccination remained protective against death for individuals who became infected during the Delta variant surge. The study also found variations in the vaccine effectiveness against death among different age groups.

SCIENCE (2022)

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News Item Multidisciplinary Sciences

COVID VACCINE MAKERS BRACE FOR A VARIANT WORSE THAN DELTA

Emily Waltz

NATURE (2021)

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Editorial Material Medicine, General & Internal

The Future of SARS-CoV-2 Vaccination - Lessons from Influenza

Arnold S. Monto

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Review Multidisciplinary Sciences

Effectiveness of non-pharmaceutical public health interventions against COVID-19: A systematic review and meta-analysis

Shabnam Iezadi et al.

Summary: The systematic review analyzed the effects of NPHIs on the COVID-19 case growth rate, death growth rate, ICU admission, and reproduction number. Results showed that the adoption of NPHIs led to decreases in daily case growth rates, death growth rates, and the COVID-19 reproduction number, as well as a decrease in COVID-19 daily ICU admission.

PLOS ONE (2021)

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Editorial Material Medical Laboratory Technology

Optimizing effectiveness of COVID-19 vaccination: will laboratory stewardship play a role?

Giuseppe Lippi et al.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2021)

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Review Genetics & Heredity

The biological and clinical significance of emerging SARS-CoV-2 variants

Kaiming Tao et al.

Summary: The emergence of multiple SARS-CoV-2 variants has significant impacts on the epidemiological and clinical aspects of the COVID-19 pandemic, including increased virus transmission rates, heightened risk of reinfection, and reduced effectiveness of neutralizing antibodies and vaccines. These variants have introduced new challenges to COVID-19 research, necessitating additional avenues of laboratory, epidemiological, and clinical studies.

NATURE REVIEWS GENETICS (2021)

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Review Immunology

Advances in Neutralization Assays for SARS-CoV-2

Yuying Lu et al.

Summary: The COVID-19 pandemic has caused a global health emergency with tremendous efforts put into controlling it. Neutralizing antibodies are of interest to researchers for their ability to protect cells and potentially be used in vaccines and patient treatment. Various neutralization assays are being developed to quantify these antibodies and explore their relationship with disease severity and potential for reinfection in patients.

SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2021)

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Article Medical Laboratory Technology