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One-Year Major Cardiovascular Events After Restrictive Versus Liberal Blood Transfusion Strategy in Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Trial

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Article Cardiac & Cardiovascular Systems

Restrictive vs liberal red blood cell transfusion strategies in patients with acute myocardial infarction and anemia: Rationale and design of the REALITY trial

Gregory Ducrocq et al.

Summary: The REALITY trial aims to compare the cost-effectiveness of implementing a restrictive vs liberal transfusion strategy in patients with AMI. The primary outcome is the ICER at 30 days, with secondary outcomes including the ICER at 1 year, and MACE at 30 days and 1 year.

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Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia The REALITY Randomized Clinical Trial

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Summary: This study compared the effects of restrictive and liberal transfusion strategies on 30-day cardiovascular events among patients with acute myocardial infarction and anemia. The findings showed that a restrictive strategy was noninferior to a liberal strategy in terms of major cardiovascular events.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

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Blood Transfusion in Myocardial Infarction Opening Old Wounds for Comparative-Effectiveness Research

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