期刊
CIRCULATION
卷 144, 期 14, 页码 1172-1185出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/CIRCULATIONAHA.121.056025
关键词
aortic disease; aortic stenosis; coronary artery bypass grafting surgery; mitral valve disease; pregnancy; sex differences; valve surgery
Cardiovascular disease is a major cause of morbidity and mortality in women, with higher morbidity and mortality rates observed in women after cardiac surgery. Gender influences the pathogenesis, pathophysiology, and surgical outcomes of cardiovascular disease.
Cardiovascular disease remains the leading cause of morbidity and mortality for women in United States and worldwide. One in 3 women dies from cardiovascular disease, and 45% of women >20 years old have some form of CVD. Historically, women have had higher morbidity and mortality after cardiac surgery. Sex influences pathogenesis, pathophysiology, presentation, postoperative complications, surgical outcomes, and survival. This review summarizes current cardiovascular surgery outcomes as they pertain to women. Specifically, this article seeks to address whether sex disparities in research, surgical referral, and outcomes still exist and to provide strategies to close these gaps. In addition, with the growing population of women of reproductive age with cardiovascular disease and cardiovascular risk factors, indications for cardiac surgery arise in pregnant women. The current review will also address the unique issues associated with this special population.
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