相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Pseudo Natural Products-Chemical Evolution of Natural Product Structure
George Karageorgis et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
Isolation, Structure Elucidation, Semi-Synthesis, and Structural Modification of C19-Diterpenoid Alkaloids from Aconitum apetalum and Their Neuroprotective Activities
Lin-Xi Wan et al.
JOURNAL OF NATURAL PRODUCTS (2021)
Early and Late Steps of Quinine Biosynthesis
Francesco Trenti et al.
ORGANIC LETTERS (2021)
P450 variations bifurcate the early terpene indole alkaloid pathway in Catharanthus roseus and Camptotheca acuminata
Justin C. Miller et al.
PHYTOCHEMISTRY (2021)
Limonin as a Starting Point for the Construction of Compounds with High Scaffold Diversity
Lucia Furiassi et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
Dual Valorization of Lignin as a Versatile and Renewable Matrix for Enzyme Immobilization and (Flow) Bioprocess Engineering
Ana I. Benitez-Mateos et al.
CHEMSUSCHEM (2021)
Diversity-oriented functionalization of 2-pyridones and uracils
Yong Shang et al.
NATURE COMMUNICATIONS (2021)
Dimethyl sulfide facilitates acid catalysed ring opening of the bicyclic monoterpenes in crude sulfate turpentine to afford p-menthadienes in good yield
Joshua D. Tibbetts et al.
GREEN CHEMISTRY (2021)
Two bi-functional cytochrome P450 CYP72 enzymes from olive (Olea europaea) catalyze the oxidative C-C bond cleavage in the biosynthesis of secoxy-iridoids - flavor and quality determinants in olive oil
Carlos E. Rodriguez-Lopez et al.
NEW PHYTOLOGIST (2021)
Enantioselective Total Synthesis of Cymoside through a Bioinspired Oxidative Cyclization of a Strictosidine Derivative
Yingchao Dou et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet-Spengler Reactions
Elisabeth Eger et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)
Heterologous overexpression of Nothapodytes foetida strictosidine synthase enhances levels of anti-cancer compound camptothecin in Ophiorrhiza rugosa
Sudhir Singh et al.
PLANT CELL TISSUE AND ORGAN CULTURE (2020)
Total Syntheses of (-)-Strictosidine and Related Indole Alkaloid Glycosides
Jukiya Sakamoto et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)
Alkaloid and iridoid glucosides from Palicourea luxurians (Rubiaceae: Palicoureeae) indicate tryptamine- and tryptophan-iridoid alkaloid formation apart the strictosidine pathway
Christoph Kornpointner et al.
PHYTOCHEMISTRY (2020)
Bioinspired Divergent Oxidative Cyclization from Strictosidine and Vincoside Derivatives: Second-Generation Total Synthesis of (-)-Cymoside and Access to an Original Hexacyclic-Fused Furo[3,2-b]indoline
Yingchao Dou et al.
CHEMISTRY-A EUROPEAN JOURNAL (2020)
Asymmetric Biocatalytic Synthesis of 1-Aryltetrahydro-β-carbolines Enabled by Substrate Walking
Elisabeth Eger et al.
CHEMISTRY-A EUROPEAN JOURNAL (2020)
Directing-Group-Free, Carbonyl Group-Promoted Catalytic C-H Arylation of Bio-Based Furans
Bogdan Ya Karlinskii et al.
ACS CATALYSIS (2020)
Computational Study of Pictet-Spenglerase Strictosidine Synthase: Reaction Mechanism and Origins of Enantioselectivity of Natural and Non-Natural Substrates
Xiang Sheng et al.
ACS CATALYSIS (2020)
Re-engineering natural products to engage new biological targets
Stephen E. Motika et al.
NATURAL PRODUCT REPORTS (2020)
Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
Sarah L. Kidd et al.
CHEMICAL SCIENCE (2020)
Ethyl lactate-involved three-component dehydrogenative reactions: biomass feedstock in diversity-oriented quinoline synthesis
Lu Yang et al.
GREEN CHEMISTRY (2020)
Haber-independent, diversity-oriented synthesis of nitrogen compounds from biorenewable chitin
Thuy Trang Pham et al.
GREEN CHEMISTRY (2020)
Sustainable catalytic protocols for the solvent free epoxidation and anti-dihydroxylation of the alkene bonds of biorenewable terpene feedstocks using H2O2 as oxidant
William B. Cunningham et al.
GREEN CHEMISTRY (2020)
Bifunctional Cytochrome P450 Enzymes Involved in Camptothecin Biosynthesis
Yun Yang et al.
ACS CHEMICAL BIOLOGY (2019)
Total Syntheses of (-)-Secologanin, (-)-5-Carboxystrictosidine, and (-)-Rubenine
Kenta Rakumitsu et al.
CHEMISTRY-A EUROPEAN JOURNAL (2019)
Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis
Evijola Llabani et al.
NATURE CHEMISTRY (2019)
Strategies for the Diversity-Oriented Synthesis of Macrocycles
Kim T. Mortensen et al.
CHEMICAL REVIEWS (2019)
Stereocomplementary Chemoenzymatic Pictet-Spengler Reactions for Formation of Rare Azepino-indole Frameworks: Discovery of Antimalarial Compounds
Yunrui Cai et al.
ACS CATALYSIS (2019)
Creating Diversity from Biomass: A Tandem Bio/Metal-Catalysis towards Chemoselective Synthesis of Densely Substituted Furans
Joao M. J. M. Ravasco et al.
CHEMSUSCHEM (2019)
Computational Framework for the Identification of Bioprivileged Molecules
Xiaowei Zhou et al.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2019)
Where Do Recent Small Molecule Clinical Development Candidates Come From?
Dean G. Brown et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Reformatsky and Blaise reactions in flow as a tool for drug discovery. One pot diversity oriented synthesis of valuable intermediates and heterocycles
L. Huck et al.
GREEN CHEMISTRY (2017)
Bioprivileged molecules: creating value from biomass
Brent H. Shanks et al.
GREEN CHEMISTRY (2017)
Strictosidine Synthase Triggered Enantioselective Synthesis of N-Substituted (S)-3,14,18,19-Tetrahydroangustines as Novel Topoisomerase I Inhibitors
Yunrui Cai et al.
ACS CHEMICAL BIOLOGY (2017)
Stereoselective Cascade to C3-Methylated Strictosidine Derivatives Employing Transaminases and Strictosidine Synthases
Eva-Maria Fischereder et al.
ACS CATALYSIS (2016)
Metabolite Diversity in Alkaloid Biosynthesis: A Multilane (Diastereomer) Highway for Camptothecin Synthesis in Camptotheca acuminata
Radin Sadre et al.
PLANT CELL (2016)
Cell-specific localization of alkaloids in Catharanthus roseus stem tissue measured with Imaging MS and Single-cell MS
Kotaro Yamamoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Problem Solving and Environmentally Benign Approach toward Diversity Oriented Synthesis of Novel 2-Amino-3-phenyl (or Alkyl) Sulfonyl-4H-chromenes at Ambient Temperature
Kapil S. Pandit et al.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2016)
Characterization of a second secologanin synthase isoform producing both secologanin and secoxyloganin allows enhanced de novo assembly of a Catharanthus roseus transcriptome
Thomas Duge de Bernonville et al.
BMC GENOMICS (2015)
De novo production of the plant-derived alkaloid strictosidine in yeast
Stephanie Brown et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Pterin-Dependent Mono-oxidation for the Microbial Synthesis of a Modified Monoterpene Indole Alkaloid
A. M. Ehrenworth et al.
ACS SYNTHETIC BIOLOGY (2015)
The seco-iridoid pathway from Catharanthus roseus
Karel Miettinen et al.
NATURE COMMUNICATIONS (2014)
A Chemical-Biological Study Reveals C9-type Iridoids as Novel Heat Shock Protein 90 (Hsp90) Inhibitors
Fabrizio Dal Piaz et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
A 7-Deoxyloganetic Acid Glucosyltransferase Contributes a Key Step in Secologanin Biosynthesis in Madagascar Periwinkle
Keisuke Asada et al.
PLANT CELL (2013)
A Pair of Tabersonine 16-Hydroxylases Initiates the Synthesis of Vindoline in an Organ-Dependent Manner in Catharanthus roseus
Sebastien Besseau et al.
PLANT PHYSIOLOGY (2013)
Diversity-oriented synthesis: producing chemical tools for dissecting biology
Cornelius J. O'Connor et al.
CHEMICAL SOCIETY REVIEWS (2012)
Scaffold Tailoring by a Newly Detected Pictet-Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework
Fangrui Wu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis
Fernando Geu-Flores et al.
NATURE (2012)
Impact of high-throughput screening in biomedical research
Ricardo Macarron et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
A Facile Chemoenzymatic Approach: One-Step Syntheses of Monoterpenoid Indole Alkaloids
Hong-Bin Zou et al.
CHEMISTRY-AN ASIAN JOURNAL (2010)
Three New O-Methyltransferases Are Sufficient for All O-Methylation Reactions of Ipecac Alkaloid Biosynthesis in Root Culture of Psychotria ipecacuanha
Taiji Nomura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Trends for diverse production strategies of plant medicinal alkaloids
Liuqing Yang et al.
NATURAL PRODUCT REPORTS (2010)
Integrating carbon-halogen bond formation into medicinal plant metabolism
Weerawat Runguphan et al.
NATURE (2010)
Diversity-oriented synthesis as a tool for the discovery of novel biologically active small molecules
Warren R. J. D. Galloway et al.
NATURE COMMUNICATIONS (2010)
Silencing of tryptamine biosynthesis for production of nonnatural alkaloids in plant culture
Weerawat Runguphan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Molecular evolutionary lines in the formation of indole alkaloids derived from secologanin
Laszlo F. Szabo
ARKIVOC (2008)
Structure-based engineering of strictosidine synthase:: Auxiliary for alkaloid libraries
Elke A. Loris et al.
CHEMISTRY & BIOLOGY (2007)
Semi-synthesis of secologanin analogues
MC Galan et al.
TETRAHEDRON LETTERS (2006)
Functional expression of an ajmaline pathway-specific esterase from Rauvolfia in a novel plant-virus expression system
M Ruppert et al.
PLANTA (2005)
A planning strategy for diversity-oriented synthesis
MD Burke et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Camptothecin-related alkaloids from hairy roots of Ophiorrhiza pumila
M Kitajima et al.
TETRAHEDRON (2002)
Chemistry of secologanin,: part 10.: Investigation of Pictet-Spengler type reactions of secologanin with histamine and its benzyl derivative
G Beke et al.
JOURNAL OF NATURAL PRODUCTS (2002)
Alkaloid formation in cell suspension cultures of Tabernaemontana elegans after feeding of tryptamine and loganin or secologanin
E Lucumi et al.
PLANT CELL TISSUE AND ORGAN CULTURE (2002)
Biotransformation of tryptamine and secologanin into plant terpenoid indole alkaloids by transgenic yeast
A Geerlings et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2001)
Regio- and stereoselectivity in the coupling reaction of secologanin with dopamine derivatives
G Beke et al.
JOURNAL OF NATURAL PRODUCTS (2001)
Short syntheses of 16-methoxycarbonyl-16,17-dehydro-antirhine and its 10-oxy derivatives from secologanin
RT Brown et al.
TETRAHEDRON LETTERS (2000)
Enantiospecific synthesis of (-)-3-iso-19,20-dehydro-β-yohimbine from secologanin:: a route to normal and pseudo stereoisomers of yohimbine
RT Brown et al.
TETRAHEDRON LETTERS (2000)
Target-oriented and diversity-oriented organic synthesis in drug discovery
SL Schreiber
SCIENCE (2000)
Chemistry of secologanin.: Part 7:: Chemical fragmentation of secologanin:: biomimetic transition from the aliphatic into the aromatic skeleton
L Károlyházy et al.
TETRAHEDRON LETTERS (2000)