☆ 4.5 Article

Sonodynamic Therapy with Metal Complexes: A New Promise in Cancer Therapy

CHEMMEDCHEM (2022)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Chemistry, Multidisciplinary

Transformable Nanosensitizer with Tumor Microenvironment-Activated Sonodynamic Process and Calcium Release for Enhanced Cancer Immunotherapy

Xuan Tan et al.

Summary: The study introduces a smart nanosonosensitizer TiO2@CaP which enhances the generation of reactive oxygen species (ROS) under ultrasound activation, inducing mitochondrial dysfunction in the tumor microenvironment and promoting immunogenic cell death, resulting in T-cell infiltration and systemic antitumor immunity. This approach holds promise for developing TME-activatable sonosensitizers with temporospatial control over antitumor responses.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

添加到收藏夹

Article Nanoscience & Nanotechnology

Water-Soluble Iridic-Porphyrin Complex for Non-invasive Sonodynamic and Sono-oxidation Therapy of Deep Tumors

Jiaen Xie et al.

Summary: A novel water-soluble iridium(III)-porphyrin sonosensitizer (IrTMPPS) was synthesized for sonodynamic therapy (SDT), showing enhanced SDT efficiency by sonocatalytically oxidizing intracellular NADH and exhibiting strong sonocytotoxicity towards cancer cells. In vivo experiments demonstrated effective tumor inhibition and anti-metastasis to the lungs in the presence of IrTMPPS and US irradiation, suggesting the potential of metal-based sonosensitizers for non-invasive deep tumor therapy.

ACS APPLIED MATERIALS & INTERFACES (2021)

添加到收藏夹

Article Oncology

Jolkinolide B targets thioredoxin and glutathione systems to induce ROS-mediated paraptosis and apoptosis in bladder cancer cells

Jun Sang et al.

Summary: JB is a novel anti-bladder cancer compound that can induce cell death in bladder cancer cells through different mechanisms, showing potential for future drug development in the treatment of bladder cancer.

CANCER LETTERS (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Organic Sonosensitizers for Sonodynamic Therapy: From Small Molecules and Nanoparticles toward Clinical Development

Dong Li et al.

Summary: Sonodynamic therapy (SDT) is a novel noninvasive therapeutic approach that combines low-intensity ultrasound with sonosensitizers. Compared to phototherapy, SDT offers advantages such as deeper tissue penetration, high accuracy, and reduced side effects. The use of organic sonosensitizers is crucial for therapeutic efficacy, and nanotechnology holds potential for overcoming obstacles and fostering innovation in this field.

SMALL (2021)

添加到收藏夹

Article Multidisciplinary Sciences

A highly potent ruthenium(II)-sonosensitizer and sonocatalyst for in vivo sonotherapy

Chao Liang et al.

Summary: This study demonstrates that [Ru(bpy)(3)](2+) can serve as a highly efficient sonosensitizer and sonocatalyst, producing therapeutic effects in cancer cells in vitro and effectively destroying mouse tumors in vivo. The findings open up possibilities for the use of polypyridinal metal complexes in noninvasive precise sonotherapy for cancer treatment, addressing the current bottleneck of a lack of efficient and safe sonosensitizers in sonodynamic therapy.

NATURE COMMUNICATIONS (2021)

添加到收藏夹

Review Biochemistry & Molecular Biology

Transfer hydrogenation catalysis in cells

Samya Banerjee et al.

Summary: This article discusses the hydrogenation reactions in biology and industrial chemical transfer hydrogenation, focusing on the use of cofactors and catalysts. The focus is on organometallic catalysts catalyzing hydrogenation of biomolecules in aqueous media and the development of metallodrugs with novel mechanisms of action. Organometallic catalysts can achieve enantioselectivity and have potential applications in living cells.

RSC CHEMICAL BIOLOGY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Necroptosis-Inducible Polymeric Nanobubbles for Enhanced Cancer Sonoimmunotherapy

Wooram Um et al.

ADVANCED MATERIALS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ultrafine Titanium Monoxide (TiO1+x) Nanorods for Enhanced Sonodynamic Therapy

Xianwen Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Metal-based photosensitizers for photodynamic therapy: the future of multimodal oncology?

Sherri A. McFarland et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2020)

添加到收藏夹

Review Chemistry, Multidisciplinary

Newly developed strategies for improving sonodynamic therapy

Xianwen Wang et al.

MATERIALS HORIZONS (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ultrasmall Oxygen-Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy

Fei Gong et al.

ADVANCED MATERIALS (2019)

添加到收藏夹

Article Optics

Mechanism of the Ru(bpy)32+ single-bubble sonochemiluminescence in neutral and alkaline aqueous solutions

B. M. Gareev et al.

JOURNAL OF LUMINESCENCE (2019)

添加到收藏夹

Article Multidisciplinary Sciences

A self-assembled Ru-Pt metallacage as a lysosome-targeting photosensitizer for 2-photon photodynamic therapy

Zhixuan Zhou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ultrasound-Activated Oxygen and ROS Generation Nanosystem Systematically Modulates Tumor Microenvironment and Sensitizes Sonodynamic Therapy for Hypoxic Solid Tumors

Jingke Fu et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Sinoporphyrin sodium based sonodynamic therapy induces anti-tumor effects in hepatocellular carcinoma and activates p53/caspase 3 axis

Enze Li et al.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Metalloporphyrin Complex-Based Nanosonosensitizers for Deep-Tissue Tumor Theranostics by Noninvasive Sonodynamic Therapy

Aiqing Ma et al.

SMALL (2019)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nanoenzyme-Augmented Cancer Sonodynamic Therapy by Catalytic Tumor Oxygenation

Piao Zhu et al.

ACS NANO (2018)

添加到收藏夹

Article Chemistry, Multidisciplinary

Metal-Organic-Framework-Derived Carbon Nanostructure Augmented Sonodynamic Cancer Therapy

Xueting Pan et al.

ADVANCED MATERIALS (2018)

添加到收藏夹

Review Biochemistry & Molecular Biology

Recent Advances in the Design of Targeted Iridium(III) Photosensitizers for Photodynamic Therapy

Huaiyi Huang et al.

CHEMBIOCHEM (2018)

添加到收藏夹

Article Acoustics

Sonochemiluminescence in an aqueous solution of Ru(bpy)3Cl2

G. L. Sharipov et al.

ULTRASONICS SONOCHEMISTRY (2018)

添加到收藏夹

Review Chemistry, Multidisciplinary

Overcoming the Achilles' heel of photodynamic therapy

Wenpei Fan et al.

CHEMICAL SOCIETY REVIEWS (2016)

添加到收藏夹

Article Chemistry, Multidisciplinary

Long-Circulating Au-TiO2 Nanocomposite as a Sonosensitizer for ROS-Mediated Eradication of Cancer

V. G. Deepagan et al.

NANO LETTERS (2016)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.