Pharmacological Chaperones for β-Galactosidase Related to GM1-Gangliosidosis and Morquio B: Recent Advances

A short survey on selected beta-galactosidase inhibitors as potential pharmacological chaperones for G(M1)-gangliosidosis and Morquio B associated mutants of human lysosomal beta-galactosidase is provided highlighting recent developments in this particular area of lysosomal storage disorders and orphan diseases.

Automated summary

The article presents a brief survey on selected beta-galactosidase inhibitors as potential pharmacological chaperones for G(M1)-gangliosidosis and Morquio B associated mutants of human lysosomal beta-galactosidase, highlighting recent developments in this specific area of lysosomal storage disorders and orphan diseases.