Bimetallic metal-organic framework derived 3D hierarchical NiO/Co3O4/C hollow microspheres on biodegradable garbage bag for sensitive, selective, and flexible enzyme-free electrochemical glucose detection

The hierarchical hollow architectured NiO/Co3O4/C is developed using the sacrificial template of Ni-Co MOF and the proximity of Ni(II)/Co(II) ions with organic ligand in Ni-Co MOF accelerates the generation of tightly pinned NiO/Co3O4/C nanostructures with carbon. The elevated charge-transfer process among the constituents of as-formulated nanocatalysts and their structural and electronic relationship are established with DFT studies. The hollow architecture of NiO/Co3O4/C exposes both the inner and outer surfaces for an effectual glucose utilization, whilst the carbon interlaced metal nanoparticles and binary metal oxide synergism enumerate, respectively, the continual electron mobility and catalytically active channels, accelerating NiO/Co3O4/C loaded Biodegradable corn starch bag's (BCSB) enzyme-free glucose sensing performance in human serum with high sensitivity and selectivity. The consistent flexible glucose electrooxidation acquired for NiO/Co3O4/C/BCSB under variant bending angles along with other unique concerts establish the bendable, binder-less, stable, reusable, and eco-friendly electrochemical probes for the evolution of revolutionary electrochemical diagnosis devices.

Automated summary

Hierarchical hollow architectured NiO/Co3O4/C is developed using sacrificial template and DFT studies, exhibiting excellent glucose sensing performance in biodegradable corn starch bags. The tight integration of nanostructures and established structural-electronic relationships contribute to the high sensitivity and selectivity. The flexible, stable, and reusable electrochemical probes show promise for revolutionary electrochemical diagnosis devices.