4.7 Article

Total syntheses of ericifolione and its analogues via a biomimetic inverse-electron-demand Diels-Alder reaction

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Total syntheses of hyperaspidinols A and B enabled by a bioinspired diastereoselective cascade sequence

Anquan Zheng et al.

Summary: A bioinspired acid-triggered cascade process was developed to diastereoselectively synthesize furo[2,3-b]chromene skeleton under mild conditions. The viability of this approach was demonstrated by the synthesis of various furo[2,3-b]chromene and pyrano[2,3-b]chromene derivatives. Moreover, the successful total syntheses of two lignan-phloroglucinol hybrids showcased the synthetic utility of this biomimetic methodology.

CHINESE CHEMICAL LETTERS (2022)

Article Plant Sciences

Phloroglucinols from Myrtaceae: attractive targets for structural characterization, biological properties and synthetic procedures

Odeta Celaj et al.

Summary: Myrtaceae plants are rich in bioactive compounds, especially acylphloroglucinols and phloroglucinol-terpene adducts. These compounds exhibit unique biological activities and have attracted interest from organic chemists for further study and synthesis techniques.

PHYTOCHEMISTRY REVIEWS (2021)

Editorial Material Plant Sciences

Natural products in drug discovery and human health

Maria-Jose U. Ferreira

PHYTOCHEMISTRY REVIEWS (2021)

Review Chemistry, Multidisciplinary

Biomimetic Dearomatization Strategies in the Total Synthesis of Meroterpenoid Natural Products

Jonathan H. George

Summary: Natural products are biosynthesized using a limited pool of starting materials, while biomimetic total synthesis attempts to replicate predisposed pathways using chemical reagents. By avoiding the use of protecting groups, researchers aim to explore the innate reactivity of biosynthetic intermediates. Biomimetic synthesis is often concise and efficient, following atom, step, and redox economies of synthesis.

ACCOUNTS OF CHEMICAL RESEARCH (2021)

Article Chemistry, Organic

Rhodomentosones A and B: Two Pairs of Enantiomeric Phloroglucinol Trimers from Rhodomyrtus tomentosa and Their Asymmetric Biomimetic Synthesis

Lu-Ming Deng et al.

Summary: Novel enantiomeric phloroglucinol trimers Rhodomentosones A and B were isolated from Rhodomyrtus tomentosa, featuring a unique fused ring system. Their structures and absolute configurations were elucidated using NMR spectroscopy, X-ray crystallography, and ECD calculation. The bioinspired synthesis of compounds 1 and 2 exhibited promising antiviral activities against respiratory syncytial virus (RSV).

ORGANIC LETTERS (2021)

Article Chemistry, Organic

Total syntheses of melodienones by redox isomerization of propargylic alcohols

Chunmao Dong et al.

Summary: A remarkable base-promoted methodology has been discovered for the rapid construction of (E)- and (Z)-gamma-oxo-alpha,beta-alkenoic ester skeletons from easily accessible vinyl propargylic alcohols through modified redox isomerization. This approach demonstrates high simplicity and efficiency with excellent tolerance of functional substituents, allowing for straightforward structural modifications of various natural products and efficient total syntheses of melodienone, homomelodienone, isomelodienone, and homoisomelodienone within 4 linear steps.

ORGANIC & BIOMOLECULAR CHEMISTRY (2021)

Article Plant Sciences

The First Racemic Total Syntheses of the Antiplasmodials Watsonianones A and B and Corymbone B

Xiao Zhang et al.

JOURNAL OF NATURAL PRODUCTS (2020)

Article Chemistry, Organic

Biomimetic Total Syntheses of Sanctis A-B with Structure Revision

Luqiong Huo et al.

ORGANIC LETTERS (2020)

Article Chemistry, Organic

The Biomimetic Total Syntheses of the Antiplasmodial Tomentosones A and B

Xiao Zhang et al.

ORGANIC LETTERS (2020)

Article Chemistry, Multidisciplinary

Isolation and Synthesis of Novel Meroterpenoids from Rhodomyrtus tomentosa: Investigation of a Reactive Enetrione Intermediate

Xu-Jie Qin et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Enzyme-Catalyzed Inverse-Electron Demand Diels-Alder Reaction in the Biosynthesis of Antifungal Ilicicolin H

Zhuan Zhang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Review Biochemistry & Molecular Biology

Promising antibacterial agents against multidrug resistant Staphylococcus aureus

Srikanth Gatadi et al.

BIOORGANIC CHEMISTRY (2019)

Review Chemistry, Multidisciplinary

Research Progress of Polycyclic Polyprenylated Acylphloroglucinols

Xing-Wei Yang et al.

CHEMICAL REVIEWS (2018)

Review Biochemistry & Molecular Biology

Structures and Bioactive Properties of Myrtucommulones and Related Acylphloroglucinols from Myrtaceae

Rosario Nicoletti et al.

MOLECULES (2018)

Article Chemistry, Medicinal

Structure-activity relationships and optimization of acyclic acylphloroglucinol analogues as novel antimicrobial agents

Haibo Tan et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)

Article Chemistry, Organic

Biomimetic-Inspired Syntheses of Myrtucommuacetalone and Myrtucommulone J

Hongxin Liu et al.

ORGANIC LETTERS (2017)

Review Chemistry, Multidisciplinary

Inverse-Electron-Demand Diels-Alder Reactions: Principles and Applications

Zhuang Mao Png et al.

CHEMISTRY-AN ASIAN JOURNAL (2017)

Review Biochemistry & Molecular Biology

Mechanistic insights into Diels-Alder reactions in natural product biosynthesis

Takuya Hashimoto et al.

CURRENT OPINION IN CHEMICAL BIOLOGY (2016)

Article Chemistry, Multidisciplinary

Biomimetic Total Syntheses of (-)-Leucoridines A and C through the Dimerization of (-)-Dihydrovalparicine

Praveen Kokkonda et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2015)

Article Chemistry, Organic

Divergent Total Syntheses of Rhodomyrtosones A and B

Anais Gervais et al.

JOURNAL OF ORGANIC CHEMISTRY (2015)

Article Chemistry, Organic

Natural Diels-Alderases: Elusive and Irresistable

Kimberly Klas et al.

JOURNAL OF ORGANIC CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

An enzymatic [4+2] cyclization cascade creates the pentacyclic core of pyrroindomycins

Zhenhua Tian et al.

NATURE CHEMICAL BIOLOGY (2015)

Article Chemistry, Multidisciplinary

Biomimetic Synthesis of the Calcineurin Phosphatase Inhibitor Dibefurin

Pascal Ellerbrock et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Organic

New Inhibitors of ROS Generation and T-Cell Proliferation from Myrtus communis

M. Iqbal Choudhary et al.

ORGANIC LETTERS (2013)

Article Chemistry, Organic

Acylphloroglucinols from Callistemon lanceolatus DC.

Suthida Rattanaburi et al.

TETRAHEDRON (2013)

Review Biochemistry & Molecular Biology

Phloroglucinol compounds of natural origin: Synthetic aspects

Inder Pal Singh et al.

NATURAL PRODUCT REPORTS (2010)

Review Biochemistry & Molecular Biology

Phloroglucinol compounds of natural origin

Inder Pal Singh et al.

NATURAL PRODUCT REPORTS (2006)

Article Chemistry, Multidisciplinary

Catalytic asymmetric synthesis of a potent thiomarinol antibiotic

X Gao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)

Article Chemistry, Organic

The source of the endo rule in the Diels-Alder reaction: Are secondary orbital interactions really necessary?

JI Garcia et al.

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Enzymatic catalysis of the Diels-Alder reaction in the biosynthesis of natural products

H Oikawa et al.

NATURAL PRODUCT REPORTS (2004)