Nematicidal activity of naphthalimide-boron cluster conjugates

This study presents the activity of a series of 1,8-naphthalimide-carborane/metallacarborane conjugates against Rhabditis sp. The carborane conjugates were the least active. Selected conjugates with cobaltacarborane (5 and 6) showed high activity. Their lethal concentration (LC50) values are substantially lower than that of the drug mebendazole.

Automated summary

This study demonstrates the activity of a series of 1,8-naphthalimide-carborane/metallacarborane conjugates against Rhabditis sp. The conjugates with cobaltacarborane showed high activity compared to other carborane conjugates.