4.7 Article

A glycol nanomedicine via a metal-coordination supramolecular self-assembly strategy for drug release monitoring and chemo-chemodynamic therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Multienzyme-like Reactivity Cooperatively Impairs Glutathione Peroxidase 4 and Ferroptosis Suppressor Protein 1 Pathways in Triple-Negative Breast Cancer for Sensitized Ferroptosis Therapy

Ke Li et al.

Summary: A Cu-TCPP(Fe) MOF-based nanosystem incorporating Au nanoparticles and RSL3 is reported in this study, which can universally suppress the antiferroptotic pathway in tumor cells and amplify ferroptotic damage. The nanosystem exhibits enzyme-like activities and can inhibit the antioxidant mechanisms involved in ferroptosis.

ACS NANO (2022)

Article Chemistry, Applied

pH-Sensitive nanoparticles based on amphiphilic imidazole/cholesterol modified hydroxyethyl starch for tumor chemotherapy

Zhilang Xu et al.

Summary: pH-responsive nanoparticles based on modified hydroxyethyl starch have been developed as an effective drug delivery system for cancer chemotherapy. These nanoparticles can accumulate in tumors and selectively release drugs in the acidic microenvironment, providing a sustained release of the drug.

CARBOHYDRATE POLYMERS (2022)

Article Chemistry, Multidisciplinary

An AIE singlet oxygen generation system based on supramolecular strategy

Minzan Zuo et al.

Summary: An AIE-based singlet oxygen generation system with chemiluminescence properties was developed through supramolecular assembly, showing significant singlet oxygen generation ability in aqueous media. The supramolecular nanoparticles exhibited enhanced fluorescence, and efficiency was further increased by introducing catalase. The system can also function as nanoreactors for photooxidation reactions, with potential applications in chemiluminescence imaging and controlled photocatalysis.

CHINESE CHEMICAL LETTERS (2021)

Article Engineering, Biomedical

Activatable nanomedicine for overcoming hypoxia-induced resistance to chemotherapy and inhibiting tumor growth by inducing collaborative apoptosis and ferroptosis in solid tumors

Jingke Fu et al.

Summary: Hypoxia is closely related to drug resistance in solid tumors. A developed nanomedicine can sensitize apoptosis and ferroptosis, effectively inhibiting tumor growth by overcoming hypoxia-induced resistance to chemotherapy.

BIOMATERIALS (2021)

Article Chemistry, Multidisciplinary

Charge-reversal biodegradable MSNs for tumor synergetic chemo/ photothermal and visualized therapy

Zimu Li et al.

Summary: A novel nanomedicine, MSN-Man-DOX@PDA-Gd-PEOz, was developed with excellent tumor targeting and penetration abilities, showing outstanding therapeutic effects in vivo and a promising prospect for clinical application.

JOURNAL OF CONTROLLED RELEASE (2021)

Article Chemistry, Multidisciplinary

Engineered Nanoscale Vanadium Metallodrugs for Robust Tumor-Specific Imaging and Therapy

Shihua Li et al.

Summary: Therapeutic metallodrugs, like vanadium nanodrugs, show promise in cancer treatment with enhanced therapy efficacy compared to traditional compounds. The controllable construction of these nanodrugs allows for tumor-selective therapy due to improved bioavailability and multiple pathways-mediated treatment. Furthermore, the VNDs can also be used for tumor-specific molecular imaging by the turn-on NIR fluorescence, offering a novel approach for in vivo cancer treatment and imaging.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Chemistry, Multidisciplinary

A Traceable, Sequential Multistage-Targeting Nanoparticles Combining Chemo/Chemodynamic Therapy for Enhancing Antitumor Efficacy

Ning Wang et al.

Summary: In this study, novel nanoparticles BDTLAG NPs were constructed to achieve a combination therapy of chemotherapy and chemodynamic therapy. The mechanisms involved passive and active targeting, pH-responsive prodrug release, and mitochondria-targeting, enhancing the anti-tumor efficacy of the nanoparticles.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Chemistry, Multidisciplinary

A Systematic Strategy of Combinational Blow for Overcoming Cascade Drug Resistance via NIR-Light-Triggered Hyperthermia

Lingna Wang et al.

Summary: A systematic combination strategy utilizing near-infrared light-triggered hyperthermia, combined with cisplatin, was proposed to overcome drug resistance. The strategy showed significant efficacy in inhibiting the growth of multidrug-resistant lung cancer in both in vitro and in vivo studies.

ADVANCED MATERIALS (2021)

Article Engineering, Biomedical

MOF-based multi-stimuli-responsive supramolecular nanoplatform equipped with macrocycle nanovalves for plant growth regulation

Jie Yang et al.

Summary: The study presents a smart plant hormone delivery system based on metal-organic frameworks (MOFs) and supramolecular nanovalves for controlled and on-demand release of plant hormones, which effectively promotes seed germination and plant growth.

ACTA BIOMATERIALIA (2021)

Article Biophysics

A pH-sensitive drug delivery system based on hyaluronic acid co-deliver doxorubicin and aminoferrocene for the combined application of chemotherapy and chemodynamic therapy

Mengheng Lei et al.

Summary: A pH-responsive drug delivery system (NPs(DOX/AFc)) was developed for codelivery of doxorubicin (DOX) and aminoferrocene (AFc) in tumor therapy, showing reduced dosage of DOX and potential synergistic effects between DOX and AFc. The system demonstrated increased generation of reactive oxygen species and loss of mitochondrial membrane potential in tumor cells, providing a new approach for combined application of chemotherapy (CT) and chemodynamic therapy (CDT).

COLLOIDS AND SURFACES B-BIOINTERFACES (2021)

Article Chemistry, Multidisciplinary

Glycocalixarene with luminescence for Warburg effect-mediated tumor imaging and targeted drug delivery

Yang Li et al.

Summary: Fluorescently labeled calix[4]arene glycoconjugates have the potential to target tumors selectively through GLUT1 recognition, and also show promise in tumor imaging.

CHEMICAL COMMUNICATIONS (2021)

Article Chemistry, Multidisciplinary

H2O2 self-supplying degradable epitope imprinted polymers for targeted fluorescence imaging and chemodynamic therapy

Hai-Yan Wang et al.

Summary: The study developed a MIP nano-platform with specific recognition of cancer cell markers, H2O2 self-supply, and controlled treatment function, which can induce cancer cell apoptosis through a Fenton-like reaction, achieving targeted tumor therapy.

NANOSCALE (2021)

Article Chemistry, Multidisciplinary

DNAzyme-Mediated Genetically Encoded Sensors for Ratiometric Imaging of Metal Ions in Living Cells

Mengyi Xiong et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Nanoscience & Nanotechnology

Selective Decoating-Induced Activation of Supramolecularly Coated Toxic Nanoparticles for Multiple Applications

Cheng Gao et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Article Materials Science, Multidisciplinary

Bioorthogonal supramolecular cell-conjugation for targeted hitchhiking drug delivery

Cheng Gao et al.

MATERIALS TODAY (2020)

Article Chemistry, Multidisciplinary

Supramolecular combination chemotherapy: a pH-responsive co-encapsulation drug delivery system

Junyi Chen et al.

CHEMICAL SCIENCE (2020)

Article Multidisciplinary Sciences

Supramolecular peptide constructed by molecular Lego allowing programmable self-assembly for photodynamic therapy

Huangtianzhi Zhu et al.

NATURE COMMUNICATIONS (2019)

Review Multidisciplinary Sciences

A view on drug resistance in cancer

Neil Vasan et al.

NATURE (2019)

Article Chemistry, Multidisciplinary

Self-Assembled Copper Amino Acid Nanoparticles for in Situ Glutathione AND H2O2 Sequentially Triggered Chemodynamic Therapy

Baojin Ma et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Review Chemistry, Multidisciplinary

Supramolecular strategy for smart windows

Sai Wang et al.

CHEMICAL COMMUNICATIONS (2019)

Article Chemistry, Multidisciplinary

NIRF turn-on nanoparticles based on the tumor microenvironment for monitoring intracellular protein delivery

Huaibao Xu et al.

CHEMICAL COMMUNICATIONS (2019)

Article Chemistry, Multidisciplinary

Control of Amphiphile Self-Assembly via Bioinspired Metal Ion Coordination

Abigail S. Knight et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Multidisciplinary Sciences

Polyrotaxane-based supramolecular theranostics

Guocan Yu et al.

NATURE COMMUNICATIONS (2018)

Review Chemistry, Multidisciplinary

Supramolecular delivery systems based on pillararenes

Weiwei Feng et al.

CHEMICAL COMMUNICATIONS (2018)

Article Chemistry, Multidisciplinary

In Situ Localization of Enzyme Activity in Live Cells by a Molecular Probe Releasing a Precipitating Fluorochrome

Hong-Wen Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Novel glycoconjugated squaraine dyes for selective optical imaging of cancer cells

M. Shimi et al.

CHEMICAL COMMUNICATIONS (2017)

Review Chemistry, Multidisciplinary

Metal-Organic Frameworks in Biomedicine

Patricia Horcajada et al.

CHEMICAL REVIEWS (2012)