Iron-Catalyzed Epoxidation of Linear α-Olefins with Hydrogen Peroxide

The combination of Fe(OTf)(2) with N-methyl bis(picolylamine) (Me-bpa) L7 enables epoxidation of linear olefins including terminal, internal, and cyclic ones, using hydrogen peroxide as terminal oxidant under mild conditions. In the presence of picolinic acid as additive improved yields of epoxides up to 75 % have been achieved.

Automated summary

The combination of Fe(OTf)(2) with N-methyl bis(picolylamine) (Me-bpa) L7 enables the epoxidation of linear olefins, including terminal, internal, and cyclic ones, using hydrogen peroxide as a terminal oxidant under mild conditions. Improved yields of epoxides up to 75% have been achieved in the presence of picolinic acid as an additive.