4.6 Article

Compartmentalized cAMP signaling in cardiac ventricular myocytes

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Physiology

Mitochondrial A-kinase anchoring proteins in cardiac ventricular myocytes

Rinzhin T. Sherpa et al.

Summary: The study identified AKAPs and PKA regulatory subunit isoforms associated with mitochondria in adult rat ventricular myocytes, particularly D-AKAP1, D-AKAP2, and ACBD3. These mitochondrial proteins may play a role in targeting PKA to the outer mitochondrial membrane, regulating mitochondrial function, and buffering cAMP diffusion.

PHYSIOLOGICAL REPORTS (2021)

Article Pharmacology & Pharmacy

Compartmentation of β2-adrenoceptor stimulated cAMP responses by phosphodiesterase types 2 and 3 in cardiac ventricular myocytes

Michael W. Rudokas et al.

Summary: This study revealed that cAMP produced by stimulation of beta(2)-adrenoceptors was unable to reach the SERCA2 pump location, and this compartmentalized response is partly due to PDE2 and PDE3 activity.

BRITISH JOURNAL OF PHARMACOLOGY (2021)

Article Cardiac & Cardiovascular Systems

Intracellular β1-Adrenergic Receptors and Organic Cation Transporter 3 Mediate Phospholamban Phosphorylation to Enhance Cardiac Contractility

Ying Wang et al.

Summary: The study revealed the presence of a pool of beta(1)AR associated with the SR in mouse hearts, which play a critical role in PKA-mediated phosphorylation of phospholamban and cardiac contractility. Activation of these intracellular beta(1)ARs relies on catecholamine transport via OCT3.

CIRCULATION RESEARCH (2021)

Article Cardiac & Cardiovascular Systems

cAMP Imaging at Ryanodine Receptors Reveals β2-Adrenoceptor Driven Arrhythmias

Filip Berisha et al.

Summary: This study established a real-time live-cell imaging approach to visualize cAMP levels in the vicinity of cardiac RyR2 in mouse and human failing cardiomyocytes under beta-AR stimulation. The findings revealed a subcellular redistribution of PDEs in cardiac hypertrophy, along with increased beta(2)-AR-dependent RyR2 phosphorylation, sarcoplasmic reticulum calcium leak, and arrhythmia susceptibility in failing mouse and human myocytes. This imaging approach may uncover potential antiarrhythmic targets for heart failure.

CIRCULATION RESEARCH (2021)

Review Cardiac & Cardiovascular Systems

A-kinase anchoring protein 1 (AKAP1) and its role in some cardiovascular diseases

Wenwen Marin

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)

Article Biochemistry & Molecular Biology

Optical Mapping of cAMP Signaling at the Nanometer Scale

Andreas Bock et al.

Article Pharmacology & Pharmacy

Compartmentalized cAMP Signaling Associated With Lipid Raft and Non-raft Membrane Domains in Adult Ventricular Myocytes

Shailesh R. Agarwal et al.

FRONTIERS IN PHARMACOLOGY (2018)

Review Cardiac & Cardiovascular Systems

Using cAMP Sensors to Study Cardiac Nanodomains

Katharina Schleicher et al.

JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2018)

Review Cardiac & Cardiovascular Systems

The Development of Compartmentation of cAMP Signaling in Cardiomyocytes: The Role of T-Tubules and Caveolae Microdomains

Navneet K. Bhogal et al.

JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE (2018)

Article Multidisciplinary Sciences

Mechanisms for restraining cAMP-dependent protein kinase revealed by subunit quantitation and cross-linking approaches

Ryan Walker-Gray et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Local protein kinase A action proceeds through intact holoenzymes

F. Donelson Smith et al.

SCIENCE (2017)

Article Cardiac & Cardiovascular Systems

Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes

Mark Richards et al.

CARDIOVASCULAR RESEARCH (2016)

Article Multidisciplinary Sciences

Mechanisms Restricting Diffusion of Intracellular cAMP

Shailesh R. Agarwal et al.

SCIENTIFIC REPORTS (2016)

Article Biochemical Research Methods

A Computational Modeling and Simulation Approach to Investigate Mechanisms of Subcellular cAMP Compartmentation

Pei-Chi Yang et al.

PLOS COMPUTATIONAL BIOLOGY (2016)

Article Cardiac & Cardiovascular Systems

Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2

Anna Zoccarato et al.

CIRCULATION RESEARCH (2015)

Review Pharmacology & Pharmacy

Creating Order from Chaos: Cellular Regulation by Kinase Anchoring

John D. Scott et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 53, 2013 (2013)

Article Cardiac & Cardiovascular Systems

Ultrastructural uncoupling between T-tubules and sarcoplasmic reticulum in human heart failure

Hai-Bo Zhang et al.

CARDIOVASCULAR RESEARCH (2013)

Article Cardiac & Cardiovascular Systems

Phosphodiesterase-2 Is Up-Regulated in Human Failing Hearts and Blunts β-Adrenergic Responses in Cardiomyocytes

Hind Mehel et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

Review Cardiac & Cardiovascular Systems

PDEs create local domains of cAMP signaling

Delphine Mika et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)

Review Cardiac & Cardiovascular Systems

Caveolae create local signalling domains through their distinct protein content, lipid profile and morphology

Robert D. Harvey et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)

Review Cell Biology

Assembly of allosteric macromolecular switches: lessons from PKA

Susan S. Taylor et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Article Cardiac & Cardiovascular Systems

Conserved expression and functions of PDE4 in rodent and human heart

Wito Richter et al.

BASIC RESEARCH IN CARDIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Disruption of the cyclic AMP phosphodiesterase-4 (PDE4)-HSP20 complex attenuates the β-agonist induced hypertrophic response in cardiac myocytes

Y. Y. Sin et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)

Article Cardiac & Cardiovascular Systems

Effects of cholesterol depletion on compartmentalized cAMP responses in adult cardiac myocytes

Shailesh R. Agarwal et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2011)

Article Biochemistry & Molecular Biology

Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110γ

Alessia Perino et al.

MOLECULAR CELL (2011)

Article Biochemical Research Methods

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

Sebastian Boerner et al.

NATURE PROTOCOLS (2011)

Article Biochemical Research Methods

Raster image correlation spectroscopy in live cells

Molly J. Rossow et al.

NATURE PROTOCOLS (2010)

Article Multidisciplinary Sciences

β2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

Viacheslav O. Nikolaev et al.

SCIENCE (2010)

Article Cardiac & Cardiovascular Systems

Role of Ca2+/Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase 1 in Mediating Cardiomyocyte Hypertrophy

Clint L. Miller et al.

CIRCULATION RESEARCH (2009)

Article Cell Biology

Cytoplasmic cAMP concentrations in intact cardiac myocytes

Radu V. Iancu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2008)

Article Pharmacology & Pharmacy

SPATIAL AND TEMPORAL ASPECTS OF cAMP SIGNALLING IN CARDIAC MYOCYTES

Radu V. Iancu et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2008)

Article Biochemistry & Molecular Biology

Signaling from β1- and β2-adrenergic receptors is defined by differential interactions with PDE4

Wito Richter et al.

EMBO JOURNAL (2008)

Review Cardiac & Cardiovascular Systems

t-tubules and sarcoplasmic in cardiac ventricular reticulum function myocytes

Clive Orchard et al.

CARDIOVASCULAR RESEARCH (2008)

Article Biochemistry & Molecular Biology

Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes

Fabrice Vandeput et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Physiology

Organization and Ca2+ regulation of adenylyl cyclases in cAMP microdomains

Debbie Willoughby et al.

PHYSIOLOGICAL REVIEWS (2007)

Review Cardiac & Cardiovascular Systems

Myocardial phosphodiesterases and regulation of cardiac contractility in health and cardiac disease

Oleg E. Osadchii

CARDIOVASCULAR DRUGS AND THERAPY (2007)

Article Neurosciences

cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes

Sunita Warrier et al.

JOURNAL OF PHYSIOLOGY-LONDON (2007)

Article Biophysics

Compartmentation of cAMP signaling in cardiac myocytes: A computational study

Radu V. Iancu et al.

BIOPHYSICAL JOURNAL (2007)

Review Neurosciences

Lipid raft microdomains and neurotransmitter signalling

John A. Allen et al.

NATURE REVIEWS NEUROSCIENCE (2007)

Article Biochemistry & Molecular Biology

Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling components

Brian P. Head et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

Localization of cardiac L-type Ca2+ channels to a caveolar macromolecular signaling complex is required for β2-adrenergic regulation

Ravi C. Balijepalli et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Review Cardiac & Cardiovascular Systems

Compartmentation of cyclic nucleotide signaling in the heart - The role of A-kinase anchoring proteins

KL Dodge-Kafka et al.

CIRCULATION RESEARCH (2006)

Review Cell Biology

Arrestin times for compartmentalised cAMP signalling and phosphodiesterase-4 enzymes

GS Baillie et al.

CURRENT OPINION IN CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Novel single chain cAMP sensors for receptor-induced signal propagation

VO Nikolaev et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Nitric oxide inhibition of adenylyl cyclase type 6 activity is dependent upon lipid rafts and caveolin signaling complexes

RS Ostrom et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Modeling β-adrenergic control of cardiac myocyte contractility in silico

JJ Saucerman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Pharmacology & Pharmacy

Muscarinic regulation of cardiac ion channels

RD Harvey et al.

BRITISH JOURNAL OF PHARMACOLOGY (2003)

Review Biochemistry & Molecular Biology

Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling

M Conti et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Multidisciplinary Sciences

β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi

GS Baillie et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Article Multidisciplinary Sciences

Targeting of cyclic AMP degradation to β2-adrenergic receptors by β-arrestins

SJ Perry et al.

SCIENCE (2002)

Article Biochemistry & Molecular Biology

Isoforms of cyclic nucleotide phosphodiesterase PDE3A in cardiac myocytes

J Wechsler et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Caveolar localization dictates physiologic signaling of β2-adrenoceptors in neonatal cardiac myocytes

Y Xiang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Review Pharmacology & Pharmacy

Caveolae: From cell biology to animal physiology

B Razani et al.

PHARMACOLOGICAL REVIEWS (2002)

Article Multidisciplinary Sciences

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering

J Zhang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

Receptor number and caveolar co-localization determine receptor coupling efficiency to adenylyl cyclase

RS Ostrom et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Review Pharmacology & Pharmacy

Compartmentation of G protein-coupled signaling pathways in cardiac myocytes

SF Steinberg et al.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2001)

Article Cell Biology

A genetically encoded, fluorescent indicator for cyclic AMP in living cells

M Zaccolo et al.

NATURE CELL BIOLOGY (2000)