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JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
Intracellular Sphingosine 1-Phosphate Contributes to Collagen Expression of Hepatic Myofibroblasts in Human Liver Fibrosis Independent of Its Receptors
Lei Xiu et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
Fei Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2015)
A Pneumocyte-Macrophage Paracrine Lipid Axis Drives the Lung toward Fibrosis
Freddy Romero et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2015)
HDAC6 Promotes Cardiac Fibrosis Progression through Suppressing RASSF1A Expression
Hui Tao et al.
CARDIOLOGY (2015)
NADPH Oxidase 4 Induces Cardiac Fibrosis and Hypertrophy Through Activating Akt/mTOR and NFκB Signaling Pathways
Qingwei David Zhao et al.
CIRCULATION (2015)
MicroRNA-21: A Central Regulator of Fibrotic Diseases Via Various Targets
Ying Huang et al.
CURRENT PHARMACEUTICAL DESIGN (2015)
Histone deacetylase inhibitor restores surfactant protein-C expression in alveolar-epithelial type II cells and attenuates bleomycin-induced pulmonary fibrosis in vivo
Chiharu Ota et al.
EXPERIMENTAL LUNG RESEARCH (2015)
Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis
Jianzhong Li et al.
KIDNEY INTERNATIONAL (2015)
mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells
N. Komatsu et al.
ONCOGENE (2015)
Aberrant expression and activity of histone deacetylases in sporadic idiopathic pulmonary fibrosis
Martina Korfei et al.
THORAX (2015)
Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells
Jie Zhang et al.
Drug Design Development and Therapy (2015)
Increased Expression of NAPDH Oxidase 4 in Systemic Sclerosis Dermal Fibroblasts Regulation by Transforming Growth Factor β
Sonsoles Piera-Velazquez et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis
Rui-Ming Liu et al.
REDOX BIOLOGY (2015)
Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway
Yifei Zhong et al.
PLOS ONE (2015)
CD36 Mediated Fatty Acid-Induced Podocyte Apoptosis via Oxidative Stress
Wei Hua et al.
PLOS ONE (2015)
An Inhibitor of NADPH Oxidase-4 Attenuates Established Pulmonary Fibrosis in a Rodent Disease Model
Elizabeth R. Jarman et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Liver Damage, Inflammation, and Enhanced Tumorigenesis after Persistent mTORC1 Inhibition
Atsushi Umemura et al.
CELL METABOLISM (2014)
Sphingosine-1-phosphate induces differentiation of cultured renal tubular epithelial cells under Rho kinase activation via the S1P2 receptor
Sho Ishizawa et al.
CLINICAL AND EXPERIMENTAL NEPHROLOGY (2014)
Sphingosine 1-phosphate signalling
Karen Mendelson et al.
DEVELOPMENT (2014)
Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice
Yan Y. Sanders et al.
EUROPEAN RESPIRATORY JOURNAL (2014)
FTY720, a Sphingosine-1 Phosphate Receptor Modulator, Improves Liver Fibrosis in a Mouse Model by Impairing the Motility of Bone Marrow-Derived Mesenchymal Stem Cells
Yaxian Kong et al.
INFLAMMATION (2014)
FTY720 attenuates paraquat-induced lung injury in mice
Jie Qian et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2014)
IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice
Dong Li et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2014)
Overexpression of c-Met and CD44v6 Receptors Contributes to Autocrine TGF-β1 Signaling in Interstitial Lung Disease
Shibnath Ghatak et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Vertical inhibition of PI3K/Akt/mTOR signaling demonstrates in vitro and in vivo anti-fibrotic activity
Minrui Liang et al.
JOURNAL OF DERMATOLOGICAL SCIENCE (2014)
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex
Ning Liang et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
IL-17A Enhances the Expression of Profibrotic Genes through Upregulation of the TGF-β Receptor on Hepatic Stellate Cells in a JNK-Dependent Manner
Thomas Fabre et al.
JOURNAL OF IMMUNOLOGY (2014)
Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes
Sarah M. Williams et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2014)
Treatment with the Immunomodulator FTY720 (Fingolimod) Significantly Reduces Renal Inflammation in Murine Unilateral Ureteral Obstruction
Shobha Thangada et al.
JOURNAL OF UROLOGY (2014)
Hypoxia-induced Bmi1 promotes renal tubular epithelial cell-mesenchymal transition and renal fibrosis via PI3K/Akt signal
Rui Du et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
Louise Hecker et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy
Masayuki Nagahashi et al.
BIOMED RESEARCH INTERNATIONAL (2014)
EGFR signaling in renal fibrosis
Shougang Zhuang et al.
KIDNEY INTERNATIONAL SUPPLEMENTS (2014)
HDAC class I inhibitor, Mocetinostat, reverses cardiac fibrosis in heart failure and diminishes CD90+ cardiac myofibroblast activation
Hikmet F. Nural-Guvener et al.
FIBROGENESIS & TISSUE REPAIR (2014)
RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species
Nagaraj Manickam et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2014)
Sphingosine Kinase 1 Deficiency Confers Protection against Hyperoxia-Induced Bronchopulmonary Dysplasia in a Murine Model Role of S1P Signaling and Nox Proteins
Anantha Harijith et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
Genetic and Pharmacological Inhibition of Rheb1-mTORC1 Signaling Exerts Cardioprotection against Adverse Cardiac Remodeling in Mice
Xiangqi Wu et al.
AMERICAN JOURNAL OF PATHOLOGY (2013)
FTY720 Ameliorates Murine Sclerodermatous Chronic Graft-Versus-Host Disease by Promoting Expansion of Splenic Regulatory Cells and Inhibiting Immune Cell Infiltration Into Skin
Doanh Le Huu et al.
ARTHRITIS AND RHEUMATISM (2013)
Nox4 modulates collagen production stimulated by transforming growth factor β1 in vivo and in vitro
Elsa C. Chan et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair
Maciej Lech et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
A Novel Immunomodulator, FTY-720 Reverses Existing Cardiac Hypertrophy and Fibrosis From Pressure Overload by Targeting NFAT ( Nuclear Factor of Activated T-cells) Signaling and Periostin
Wei Liu et al.
CIRCULATION-HEART FAILURE (2013)
Fish Omega-3 Fatty Acids Induce Liver Fibrosis in the Treatment of Bile Duct-Ligated Rats
Chih-Cheng Chen et al.
DIGESTIVE DISEASES AND SCIENCES (2013)
Sphingosine kinase/sphingosine 1-phosphate (S1P)/S1P receptor axis is involved in liver fibrosis-associated angiogenesis
Le Yang et al.
JOURNAL OF HEPATOLOGY (2013)
Rheb/mTORC1 Signaling Promotes Kidney Fibroblast Activation and Fibrosis
Lei Jiang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)
p-Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase
Hiroshi Watanabe et al.
KIDNEY INTERNATIONAL (2013)
Curcumin ameliorates diabetic nephropathy by inhibiting the activation of the SphK1-S1P signaling pathway
Juan Huang et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2013)
A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling
Yuqing Liu et al.
LIVER INTERNATIONAL (2013)
Class II HDAC Inhibition Hampers Hepatic Stellate Cell Activation by Induction of MicroRNA-29
Inge Mannaerts et al.
PLOS ONE (2013)
Inhibition of Rho-kinase alleviates peritoneal fibrosis and angiogenesis in a rat model of peritoneal dialysis
Weisheng Peng et al.
RENAL FAILURE (2013)
FTY720 attenuates tubulointerstitial inflammation and fibrosis in subtotally nephrectomized rats
Hai-Feng Ni et al.
RENAL FAILURE (2013)
IL-22 contributes to TGF-β1-mediated epithelial-mesenchymal transition in asthmatic bronchial epithelial cells
Jill R. Johnson et al.
RESPIRATORY RESEARCH (2013)
TGF-β Induces Acetylation of Chromatin and of Ets-1 to Alleviate Repression of miR-192 in Diabetic Nephropathy
Mitsuo Kato et al.
SCIENCE SIGNALING (2013)
Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts
S. K. Huang et al.
CELL DEATH & DISEASE (2013)
Sphingosine-1-phosphate acts as a key molecule in the direct mediation of renal fibrosis
Shunji Shiohira et al.
PHYSIOLOGICAL REPORTS (2013)
Bone Marrow-Derived Mesenchymal Stem Cells Differentiate to Hepatic Myofibroblasts by Transforming Growth Factor-β1 via Sphingosine Kinase/Sphingosine 1-Phosphate (S1P)/S1P Receptor Axis
Le Yang et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Liver fibrosis and hepatocyte apoptosis are attenuated by GKT137831, a novel NOX4/NOX1 inhibitor in vivo
Joy X. Jiang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Role of Nox4 in murine models of kidney disease
Andrea Babelova et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
TGF-beta 1 induced fibroblast proliferation is mediated by the FGF-2/ERK pathway
Li Xiao et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2012)
Regulation of Autophagy and Its Associated Cell Death by Sphingolipid Rheostat RECIPROCAL ROLE OF CERAMIDE AND SPHINGOSINE 1-PHOSPHATE IN THE MAMMALIAN TARGET OF RAPAMYCIN PATHWAY
Makoto Taniguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts
Guochun Chen et al.
PLOS ONE (2012)
Heparin-Binding EGF-Like Growth Factor Induces Heart Interstitial Fibrosis via an Akt/mTor/p70s6k Pathway
Hong Lian et al.
PLOS ONE (2012)
NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death during Liver Fibrosis Development
Patricia Sancho et al.
PLOS ONE (2012)
Sphingosine-1-phosphate is increased in patients with idiopathic pulmonary fibrosis and mediates epithelial to mesenchymal transition
Javier Milara et al.
THORAX (2012)
The extracellular matrix: an active or passive player in fibrosis?
Thomas N. Wight et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2011)
TRIP-1 regulates TGF-β1-induced epithelial-mesenchymal transition of human lung epithelial cell line A549
Ricardo E. Perez et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2011)
Transforming growth factor-β2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling
Damian Medici et al.
BIOCHEMICAL JOURNAL (2011)
Collagen triple helix repeat containing-1 inhibits transforming growth factor-β1-induced collagen type I expression in keloid
J. Li et al.
BRITISH JOURNAL OF DERMATOLOGY (2011)
Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration
Graham M. Strub et al.
FASEB JOURNAL (2011)
Hypoxia-Inducible Transcription Factor 2α Promotes Steatohepatitis Through Augmenting Lipid Accumulation, Inflammation, and Fibrosis
Aijuan Qu et al.
HEPATOLOGY (2011)
T beta RI/Alk5-independent T beta RII signaling to ERK1/2 in human skin cells according to distinct levels of T beta RII expression
Balaji Bandyopadhyay et al.
JOURNAL OF CELL SCIENCE (2011)
Sphingosine 1-phosphate (S1P)/S1P receptors are involved in human liver fibrosis by action on hepatic myofibroblasts motility
Changyong Li et al.
JOURNAL OF HEPATOLOGY (2011)
Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression
Jennifer Haynes et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Bioactive lipoxygenase metabolites stimulation of NADPH oxidases and reactive oxygen species
Kyung-Jin Cho et al.
MOLECULES AND CELLS (2011)
Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis
Naoki Washida et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2011)
S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species
Noriko Takuwa et al.
CARDIOVASCULAR RESEARCH (2010)
Chronic Administration of Valproic Acid Inhibits Activation of Mouse Hepatic Stellate Cells In Vitro and In Vivo
Inge Mannaerts et al.
HEPATOLOGY (2010)
NAD(P)H Oxidase Mediates TGF-beta 1-Induced Activation of Kidney Myofibroblasts
Corry D. Bondi et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2010)
Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2
Sergio E. Alvarez et al.
NATURE (2010)
HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes
Matt J. Barter et al.
MATRIX BIOLOGY (2010)
Noncanonical TGF-beta pathways, mTORC1 and Ab1, in renal interstitial fibrogenesis
Shinong Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2010)
Involvement of Sphingosine 1-Phosphate (SIP)/S1P3 Signaling in Cholestasis-Induced Liver Fibrosis
Changyong Li et al.
AMERICAN JOURNAL OF PATHOLOGY (2009)
Abrogation of TGF-β1-induced fibroblast-myofibroblast differentiation by histone deacetylase inhibition
Weichao Guo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Distinct Roles for Mammalian Target of Rapamycin Complexes in the Fibroblast Response to Transforming Growth Factor-beta
Rod A. Rahimi et al.
CANCER RESEARCH (2009)
Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-β-stimulated collagen production by cardiac fibroblasts
Nicole Gellings Lowe et al.
CARDIOVASCULAR RESEARCH (2009)
Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM
Christian Maeurer et al.
CELLULAR SIGNALLING (2009)
NADPH oxidases are responsible for the failure of nitric oxide to inhibit migration of smooth muscle cells exposed to high glucose
XiaoYong Tong et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Nox proteins in signal transduction
David I. Brown et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Homing of bone marrow mesenchymal stem cells mediated by sphingosine 1-phosphate contributes to liver fibrosis
Changyong Li et al.
JOURNAL OF HEPATOLOGY (2009)
NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
Louise Hecker et al.
NATURE MEDICINE (2009)
The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors
Atsuo Kawahara et al.
SCIENCE (2009)
Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate
Nitai C. Hait et al.
SCIENCE (2009)
Inhibition of histone deacetylase activity attenuates renal fibroblast activation and interstitial fibrosis in obstructive nephropathy
Maoyin Pang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2009)
Rho-associated kinase are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts
Alfiya Akhmetshina et al.
ARTHRITIS AND RHEUMATISM (2008)
The Spinster Homolog, Two of Hearts, Is Required for Sphingosine 1-Phosphate Signaling in Zebrafish
Nick Osborne et al.
CURRENT BIOLOGY (2008)
RXR agonists inhibit high-glucose-induced oxidative stress by repressing PKC activity in human endothelial cells
Dajun Chai et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Nox4 NAD(P)H oxidase mediates Src-dependent tyrosine phosphorylation of PDK-1 in response to angiotensin II - Role in mesangial cell hypertrophy and fibronectin expression
Karen Block et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-β
Motozo Yamashita et al.
MOLECULAR CELL (2008)
The type I TGF-β receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner
Alessandro Sorrentino et al.
NATURE CELL BIOLOGY (2008)
Principles of bioactive lipid signalling: lessons from sphingolipids
Yusuf A. Hannun et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Characterization of ceramide synthase 2 - Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
Elad L. Laviad et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Mitogenic signaling via platelet-derived growth factor β in metanephric mesenchymal cells
Brent Wagner et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2007)
Histone deacetylase 4 is required for TGFβ1-induced myofibroblastic differentiation
Wendy Glenisson et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2007)
TGF-β activates Erk MAP kinase signalling through direct phosphorylation of ShcA
Matt K. Lee et al.
EMBO JOURNAL (2007)
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation
Lena Serrander et al.
BIOCHEMICAL JOURNAL (2007)
Trichostatin a prevents the accumulation of extracellular matrix in a mouse model of bleomycin-induced skin fibrosis
Lars C. Huber et al.
ARTHRITIS AND RHEUMATISM (2007)
Reactive nitrogen and oxygen species activate different sphingomyelinases to induce apoptosis in airway epithelial cells
S. Sianna Castillo et al.
EXPERIMENTAL CELL RESEARCH (2007)
Nox1 redox signaling mediates oncogenic Ras-induced disruption of stress fibers and focal adhesions by down-regulating Rho
Masahiro Shinohara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Inhibition of PDGF, VEGF and FGF signalling attenuates fibrosis
N. I. Chaudhary et al.
EUROPEAN RESPIRATORY JOURNAL (2007)
Trichostatin A blocks TGF-β-induced collagen gene expression in skin fibroblasts:: Involvement of Sp1
Asish K. Ghosh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Cell contact-dependent epithelial-myofibroblast kinase-phospho-myosin regulation of transition via the Rho-Rho pathway
Lingzhi Fan et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
The immunosuppressant drug FTY720 inhibits cytosohc phospholipase A2 independently of sphingosine-1-phosphate receptors
Shawn G. Payne et al.
BLOOD (2007)
Smad3 is acetylated by p300/CBP to regulate its transactivation activity
Y. Inoue et al.
ONCOGENE (2007)
Dynamic changes in chromatin acetylation and the expression of histone acetyltransferases and histone deacetylases regulate the SM22α transcription in response to Smad3-mediated TGFβI1 signaling
Ping Qiu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
TGF-β regulates differentially the proliferation of fetal and adult human skin fibroblasts via the activation of PKA and the autocrine action of FGF-2
Christina C. Giannouli et al.
CELLULAR SIGNALLING (2006)
The ADP-stimulated NADPH oxidase activates the ASK-1/MKK4/JNK pathway in alveolar macrophages
Honglei Liu et al.
FREE RADICAL RESEARCH (2006)
IL-13 signaling through the IL-13 alpha 2 receptor is involved in induction of TGF-beta 1 production and fibrosis
S Fichtner-Feigl et al.
NATURE MEDICINE (2006)
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney
Y Gorin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
NAD(P)H oxidase 4 mediates transforming growth factor-β1-induced differentiation of cardiac fibroblasts into myofibroblasts
I Cucoranu et al.
CIRCULATION RESEARCH (2005)
The balance between acetylation and deacetylation controls Smad7 stability
M Simonsson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Histone deacetylase HDAC8 associates with smooth muscle α-actin and is essential for smooth muscle cell contractility
D Waltregny et al.
FASEB JOURNAL (2005)
Overlapping signaling pathways of sphingosine 1-phosphate and TGF-β in the murine Langerhans cell line XS52
HH Radeke et al.
JOURNAL OF IMMUNOLOGY (2005)
Human urotensin II is a novel activator of NADPH oxidase in human pulmonary artery smooth muscle cells
T Djordjevic et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2005)
Expression of neutral sphingomyelinase-2 (NSMase-2) in primary rat hepatocytes modulates IL-β-induced JNK activation
AA Karakashian et al.
FASEB JOURNAL (2004)
Sphingosine 1-phosphate cross-activates the Smad signaling cascade and mimics transforming growth factor-β-induced cell responses
CY Xin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues
D Waltregny et al.
AMERICAN JOURNAL OF PATHOLOGY (2004)
Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation
SM Pitson et al.
EMBO JOURNAL (2003)
NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
S Sakon et al.
EMBO JOURNAL (2003)
A synthetic peptide from transforming growth factor β type III receptor inhibits liver fibrogenesis in rats with carbon tetrachloride liver injury
IJ Ezquerro et al.
CYTOKINE (2003)
Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation
H Matsue et al.
JOURNAL OF IMMUNOLOGY (2002)
HDAC6 is a microtubule-associated deacetylase
C Hubbert et al.
NATURE (2002)
Y-27632 prevents tubulointerstitial fibrosis in mouse kidneys with unilateral ureteral obstruction
K Nagatoya et al.
KIDNEY INTERNATIONAL (2002)
Interleukin-4-and interleukin-13-enhanced transforming growth factor-β2 production in cultured human bronchial epithelial cells is attenuated by interferon-γ
FQ Wen et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2002)
Sphingosine kinase interacts with TRAF2 and dissects tumor necrosis factor-α signaling
P Xia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA
S Edlund et al.
MOLECULAR BIOLOGY OF THE CELL (2002)
Upregulation of the vascular NAD(P)H-oxidase isoforms Nox1 and Nox4 by the renin-angiotensin system in vitro and in vivo
M Wingler et al.
FREE RADICAL BIOLOGY AND MEDICINE (2001)
Duration of nuclear NF-κB action regulated by reversible acetylation
LF Chen et al.
SCIENCE (2001)
Homologs of gp91phox:: cloning and tissue expression of Nox3, Nox4, and Nox5
GJ Cheng et al.
GENE (2001)
Synergistic cooperation between Sp1 and Smad3/Smad4 mediates transforming growth factor β1 stimulation of α2(I)-collagen (COL1A2) transcription
W Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Identification of Renox, an NAD(P)H oxidase in kidney
M Geiszt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
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