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Xaria X. Li et al.
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Louise S. Dalboge et al.
PEPTIDES (2021)
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Elena Bresciani et al.
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Jessica A. Rowley et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
The VGF-derived Peptide TLQP21 Impairs Purinergic Control of Chemotaxis and Phagocytosis in Mouse Microglia
Nirmeen Elmadany et al.
JOURNAL OF NEUROSCIENCE (2020)
VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice
Farida El Gaamouch et al.
MOLECULAR NEURODEGENERATION (2020)
Photoperiodic changes in adiposity increase sensitivity of female Siberian hamsters to systemic VGF derived peptide TLQP-21
Carlo Lisci et al.
PLOS ONE (2019)
Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21
Bhavani S. Sahu et al.
CELL REPORTS (2019)
HSPA8/HSC70 in Immune Disorders: A Molecular Rheostat that Adjusts Chaperone-Mediated Autophagy Substrates
Srinivasa Reddy Bonam et al.
CELLS (2019)
The C1q Receptors: Focus on gC1qR/p33 (C1qBP, p32, HABP-1)1
Berhane Ghebrehiwet et al.
SEMINARS IN IMMUNOLOGY (2019)
VGF and its C-terminal peptide TLQP-62 in ventromedial prefrontal cortex regulate depression-related behaviors and the response to ketamine
Cheng Jiang et al.
NEUROPSYCHOPHARMACOLOGY (2019)
VGF: a biomarker and potential target for the treatment of neuropathic pain?
Nadia Soliman et al.
PAIN REPORTS (2019)
VGF function in depression and antidepressant efficacy
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MOLECULAR PSYCHIATRY (2018)
Clearance kinetics of the VGF-derived neuropeptide TLQP-21
ZengKui Guo et al.
NEUROPEPTIDES (2018)
Structures of C1-IgG1 provide insights into how danger pattern recognition activates complement
Deniz Ugurlar et al.
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Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727
Nathan Robertson et al.
NATURE (2018)
Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer's Disease
Alexandra Litvinchuk et al.
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Study of the Tissue Distribution o f TLQP-21 in Mice Using [18F]JMV5763, a Radiolabeled Analog Prepared via [18F]Aluminum Fluoride Chelation Chemistry
Elia A. Turolla et al.
FRONTIERS IN PHARMACOLOGY (2018)
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
Benjamin E. Housden et al.
NATURE REVIEWS GENETICS (2017)
Complement 3a receptor in dorsal horn microglia mediates pronociceptive neuropeptide signaling
Suzanne Doolen et al.
GLIA (2017)
Monitoring C3aR Expression Using a Floxed tdTomato-C3aR Reporter Knock-in Mouse
Katharina M. Quell et al.
JOURNAL OF IMMUNOLOGY (2017)
The human VGF-derived bioactive peptide TLQP-21 binds heat shock 71 kDa protein 8 (HSPA8) on the surface of SH-SY5Y cells
Shamim Akhter et al.
PLOS ONE (2017)
The Prohormone VGF Regulates β Cell Function via Insulin Secretory Granule Biogenesis
Samuel B. Stephens et al.
CELL REPORTS (2017)
Pharmacological and Biochemical Characterization of TLQP-21 Activation of a Binding Site on CHO Cells
Laura Molteni et al.
FRONTIERS IN PHARMACOLOGY (2017)
The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis
Cheryl Cero et al.
MOLECULAR METABOLISM (2017)
Hypothalamic over-expression of VGF in the Siberian hamster increases energy expenditure and reduces body weight gain
Jo E. Lewis et al.
PLOS ONE (2017)
Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis
Maria Razzoli et al.
MOLECULAR METABOLISM (2016)
VGF Protein and Its C-Terminal Derived Peptides in Amyotrophic Lateral Sclerosis: Human and Animal Model Studies
Carla Brancia et al.
PLOS ONE (2016)
Is the Complement Activation Product C3a a Proinflammatory Molecule? Re-evaluating the Evidence and the Myth
Liam G. Coulthard et al.
JOURNAL OF IMMUNOLOGY (2015)
The VGF-derived peptide TLQP-62 modulates insulin secretion and glucose homeostasis
Pamela Petrocchi-Passeri et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2015)
VGF and Its C-Terminal Peptide TLQP-62 Regulate Memory Formation in Hippocampus via a BDNF-TrkB-Dependent Mechanism
Wei-Jye Lin et al.
JOURNAL OF NEUROSCIENCE (2015)
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
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NATURE (2015)
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FRONTIERS IN IMMUNOLOGY (2015)
VGF Peptide Profiles in Type 2 Diabetic Patients' Plasma and in Obese Mice
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PLOS ONE (2015)
The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure
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FASEB JOURNAL (2014)
The VGF-derived peptide TLQP-21 contributes to inflammatory and nerve injury-induced hypersensitivity
Carolyn A. Fairbanks et al.
PAIN (2014)
The TLQP-21 Peptide Activates the G-Protein-Coupled Receptor C3aR1 via a Folding-upon-Binding Mechanism
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STRUCTURE (2014)
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AUTOPHAGY (2013)
Biophysical characterization of a binding site for TLQP-21, a naturally occurring peptide which induces resistance to obesity
V. Cassina et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2013)
C5aR and C3aR antagonists each inhibit diet-induced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
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FASEB JOURNAL (2013)
Complement activation associated with polysorbate 80 in beagle dogs
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INTERNATIONAL IMMUNOPHARMACOLOGY (2013)
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Ya-Chun Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Identification of the C3a Receptor (C3AR1) as the Target of the VGF-derived Peptide TLQP-21 in Rodent Cells
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JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Neuropeptide TLQP-21, a VGF Internal Fragment, Modulates Hormonal Gene Expression and Secretion in GH3 Cell Line
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PHARMACOLOGICAL REVIEWS (2013)
Implication of the VGF-derived peptide TLQP-21 in mouse acute and chronic stress responses
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BEHAVIOURAL BRAIN RESEARCH (2012)
Characterization of a novel peripheral pro-lipolytic mechanism in mice: role of VGF-derived peptide TLQP-21
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BIOCHEMICAL JOURNAL (2012)
A VGF-Derived Peptide Attenuates Development of Type 2 Diabetes via Enhancement of Islet β-Cell Survival and Function
Samuel B. Stephens et al.
CELL METABOLISM (2012)
Complement activation by polyethoxylated pharmaceutical surfactants: Cremophor-EL, Tween-80 and Tween-20
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EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2012)
Characterization of the reproductive effects of the anorexigenic VGF-derived peptide TLQP-21: in vivo and in vitro studies in male rats
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AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
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Distinct and Shared Roles of β-Arrestin-1 and β-Arrestin-2 on the Regulation of C3a Receptor Signaling in Human Mast Cells
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PLOS ONE (2011)
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BRITISH JOURNAL OF PHARMACOLOGY (2009)
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Yael Mamane et al.
DIABETES (2009)
Chronic intracerebroventricular injection of TLQP-21 prevents high fat diet induced weight gain in fast weight-gaining mice
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JOURNAL OF NEUROSCIENCE (2009)
The role of the anaphylatoxins in health and disease
Andreas Klos et al.
MOLECULAR IMMUNOLOGY (2009)
Identification of ligand effector binding sites in transmembrane regions of the human G protein-coupled C3a receptor
Jianzhong Sun et al.
PROTEIN SCIENCE (2009)
Cyclic AMP plays a critical role in C3a-receptor-mediated regulation of dendritic cells in antigen uptake and T-cell stimulation
Ke Li et al.
BLOOD (2008)
The VGF-derived peptide TLQP-21: A new modulatory peptide for inflammatory pain
Roberto Rizzi et al.
NEUROSCIENCE LETTERS (2008)
TLQP-21, a neuroendocrine VGF-derived peptide, prevents cerebellar granule cells death induced by serum and potassium deprivation
Cinzia Severini et al.
JOURNAL OF NEUROCHEMISTRY (2008)
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Alessandro Bartolomucci et al.
GENES AND NUTRITION (2007)
VGF-derived peptide, TLQP-21, regulates food intake and body weight in Siberian hamsters
Preeti H. Jethwa et al.
ENDOCRINOLOGY (2007)
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A. Bartolomucci et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The C3a receptor antagonist SB 290157 has agonist activity
MC Mathieu et al.
IMMUNOLOGY LETTERS (2005)
Processing, distribution, and function of VGF, a neuronal and endocrine peptide precursor
A Levi et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2004)
Identification of a selective nonpeptide antagonist of the anaphylatoxin C3a receptor that demonstrates antiinflammatory activity in animal models
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JOURNAL OF IMMUNOLOGY (2001)
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