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Pauli Virtanen et al.
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Maik Behrens et al.
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Array programming with NumPy
Charles R. Harris et al.
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Sung-Joon Lee et al.
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Aldenor G. Santos et al.
SCIENTIFIC REPORTS (2019)
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Kun Liu et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2018)
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Stefanie Nowak et al.
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Andrew Waterhouse et al.
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Shifan Yang et al.
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Ching-Ju Tsai et al.
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Selectivity determinants of GPCR-G-protein binding
Tilman Flock et al.
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In situ click chemistry generation of cyclooxygenase-2 inhibitors
Atul Bhardwaj et al.
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Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness
Michiru Nishita et al.
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Anu Thomas et al.
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Fabrizio Fierro et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2017)
GPCRdb: the G protein-coupled receptor database - an introduction
C. Munk et al.
BRITISH JOURNAL OF PHARMACOLOGY (2016)
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Rafik Karaman et al.
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Dean P. Staus et al.
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Vaclav Cvicek et al.
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Ranjan V. Mannige et al.
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The structure-function role of C-terminus in human bitter taste receptor T2R4 signaling
Jasbir Upadhyaya et al.
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Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism
James A. R. Dalton et al.
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Agne Malki et al.
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Claire A. de March et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
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Sai P. Pydi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
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Anat Levit et al.
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Jennifer L. Miller-Gallacher et al.
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Allosteric sodium in class A GPCR signaling
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Activation and dynamic network of the M2 muscarinic receptor
Yinglong Miao et al.
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How broadly tuned olfactory receptors equally recognize their agonists. Human OR1G1 as a test case
Landry Charlier et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Recent Advances in Structure and Function Studies on Human Bitter Taste Receptors
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OPM database and PPM web server: resources for positioning of proteins in membranes
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Structural insights into agonist-induced activation of G-protein-coupled receptors
Xavier Deupi et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2011)
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Nisha Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Independent HHsearch, Needleman-Wunsch-Based, and Motif Analyses Reveal the Overall Hierarchy for Most of the G Protein-Coupled Receptor Families
Karl J. V. Nordstrom et al.
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Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
Fabian Sievers et al.
MOLECULAR SYSTEMS BIOLOGY (2011)
Probenecid Inhibits the Human Bitter Taste Receptor TAS2R16 and Suppresses Bitter Perception of Salicin
Tiffani A. Greene et al.
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Modulation of Bitter Taste Perception by a Small Molecule hTAS2R Antagonist
Jay P. Slack et al.
CURRENT BIOLOGY (2010)
Characterization of the β-D-Glucopyranoside Binding Site of the Human Bitter Taste Receptor hTAS2R16
Takanobu Sakurai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Insights into the Binding of Phenyltiocarbamide (PTC) Agonist to Its Target Human TAS2R38 Bitter Receptor
Xevi Biarnes et al.
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Anne Brockhoff et al.
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Jalview Version 2-a multiple sequence alignment editor and analysis workbench
Andrew M. Waterhouse et al.
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Cedrick D. Dotson et al.
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Positive selection on a high-sensitivity allele of the human bitter-taste receptor TAS2R16
N Soranzo et al.
CURRENT BIOLOGY (2005)
The repertoire of G-protein-coupled receptors in fully sequenced genomes
R Fredriksson et al.
MOLECULAR PHARMACOLOGY (2005)
The receptors and coding logic for bitter taste
KL Mueller et al.
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The G-protein-coupled receptors in the human genome form five main families.: Phylogenetic analysis, paralogon groups, and fingerprints
R Fredriksson et al.
MOLECULAR PHARMACOLOGY (2003)
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E Adler et al.
CELL (2000)
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