Microglia modulate neurodevelopment in human neuroimmune organoids

Dissecting contributions of microglia to human brain development and disease pathogenesis requires modeling interactions between these microglia and their local environment. In this issue of Cell Stem Cell, Popova et al. (2021) propose a transcriptomic microglia report card and create a neuroimmune organoid to model complex interactions involving human microglia.

Automated summary

Creating a neuroimmune organoid allows for the study of complex interactions involving human microglia in brain development and disease pathogenesis.