4.3 Article

Ceruloplasmin Deficiency Impaired Brain Iron Metabolism and Behavior in Mice

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Review Biochemistry & Molecular Biology

Ceruloplasmin Deamidation in Neurodegeneration: From Loss to Gain of Function

Alan Zanardi et al.

Summary: Neurodegenerative disorders can lead to modifications of ceruloplasmin, including oxidation and deamidation, resulting in loss of enzymatic activity and gain of new functions. Deamidated ceruloplasmin can affect cell functioning and trigger intracellular signaling, potentially causing detrimental effects on different target cells in the brain.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Review Biochemistry & Molecular Biology

The essential elements of Alzheimer's disease

Peng Lei et al.

Summary: Despite numerous phase 3 clinical trials targeting amyloid plaque in AD treatment, their effectiveness remains uncertain. This study highlights the importance of other neurochemical abnormalities in the AD brain as potential therapeutic targets, focusing on elementomic signatures of essential elements like iron, copper, zinc, and selenium. Revisiting discoveries in the AD field may offer new insights into pathogenesis and therapeutic strategies.

JOURNAL OF BIOLOGICAL CHEMISTRY (2021)

Review Neurosciences

Does Ceruloplasmin Defend Against Neurodegenerative Diseases?

Bo Wang et al.

CURRENT NEUROPHARMACOLOGY (2019)

Article Neurosciences

Ceruloplasmin Plays a Neuroprotective Role in Cerebral lschemia

Fari Ryan et al.

FRONTIERS IN NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

Ceruloplasmin, a Potential Therapeutic Agent for Alzheimer's Disease

Ya-Shuo Zhao et al.

ANTIOXIDANTS & REDOX SIGNALING (2018)

Article Biochemistry & Molecular Biology

Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes

Jiashuo Zheng et al.

FEBS LETTERS (2018)

Article Biochemistry & Molecular Biology

Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis

En Xu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Review Neurosciences

Iron and Alzheimer's Disease: From Pathogenesis to Therapeutic Implications

Jun-Lin Liu et al.

FRONTIERS IN NEUROSCIENCE (2018)

Article Gastroenterology & Hepatology

Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin

Brie K. Fuqua et al.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY (2018)

Article Medicine, Research & Experimental

Ceruloplasmin replacement therapy ameliorates neurological symptoms in a preclinical model of aceruloplasminemia

Alan Zanardi et al.

EMBO MOLECULAR MEDICINE (2018)

Article Nutrition & Dietetics

Current understanding of iron homeostasis

Gregory J. Anderson et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2017)

Article Biochemistry & Molecular Biology

Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.

Liangliang Zhao et al.

JOURNAL OF NEUROCHEMISTRY (2015)

Review Medical Laboratory Technology

The Molecular Biology of Human Iron Metabolism

William E. Winter et al.

LABMEDICINE (2014)

Review Physiology

SYSTEMIC IRON HOMEOSTASIS

Tomas Ganz

PHYSIOLOGICAL REVIEWS (2013)

Review Nutrition & Dietetics

Multi-Copper Oxidases and Human Iron Metabolism

Ganna Vashchenko et al.

NUTRIENTS (2013)

Review Geriatrics & Gerontology

Retinal iron homeostasis in health and disease

Delu Song et al.

FRONTIERS IN AGING NEUROSCIENCE (2013)

Review Biochemistry & Molecular Biology

Ferroportin-mediated iron transport: Expression and regulation

Diane M. Ward et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)

Review Biochemistry & Molecular Biology

Regulation of cellular iron metabolism

Jian Wang et al.

BIOCHEMICAL JOURNAL (2011)

Article Biochemistry & Molecular Biology

Ceruloplasmin in neurodegenerative diseases

Sarah J. Texel et al.

BIOCHEMICAL SOCIETY TRANSACTIONS (2008)

Article Multidisciplinary Sciences

Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

P Hahn et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Neurosciences

Iron, brain ageing and neurodegenerative disorders

L Zecca et al.

NATURE REVIEWS NEUROSCIENCE (2004)

Article Biochemistry & Molecular Biology

Quantitative evaluation of expression of iron-metabolism genes in ceruloplasmin-deficient mice

K Yamamoto et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2002)

Review Neurosciences

Rethinking the role of ceruloplasmin in brain iron metabolism

ZM Qian et al.

BRAIN RESEARCH REVIEWS (2001)