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Curtis W. Bacon et al.
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Yebin Lu et al.
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Zhiyu Dai et al.
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Samantha M. Yeligar et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2018)
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Thenappan Thenappan et al.
BMJ-BRITISH MEDICAL JOURNAL (2018)
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Thenappan Thenappan et al.
BMJ-BRITISH MEDICAL JOURNAL (2018)
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Hanghang Zhang et al.
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Exosomal 15-LO2 mediates hypoxia-induced pulmonary artery hypertension in vivo and in vitro
Min Zhang et al.
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Liang Zhou et al.
BRITISH JOURNAL OF CANCER (2018)
Vascular peroxidase 1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferation, apoptosis resistance and migration
Baiyang You et al.
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The emerging picture of CDK9/P-TEFb: more than 20 years of advances since PITALRE
Nikolas Ferreira dos Santos Paparidis et al.
MOLECULAR BIOSYSTEMS (2017)
The cancer theory of pulmonary arterial hypertension
Olivier Boucherat et al.
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Identification of Atuveciclib (BAY 1143572), the First Highly Selective, Clinical PTEFb/CDK9 Inhibitor for the Treatment of Cancer
Ulrich Luecking et al.
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Stephen L. Archer
CIRCULATION (2017)
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Soni Savai Pullamsettit et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma
Justin L. Tan et al.
MOLECULAR CELL (2016)
A global view of pulmonary hypertension
Marius M. Hoeper et al.
LANCET RESPIRATORY MEDICINE (2016)
Selective CDK9 inhibition overcomes TRAIL resistance by concomitant suppression of cFlip and Mcl-1
J. Lemke et al.
CELL DEATH AND DIFFERENTIATION (2014)
CDK9-mediated transcription elongation is required for MYC addiction in hepatocellular carcinoma
Chun-Hao Huang et al.
GENES & DEVELOPMENT (2014)
LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis
Xiaodan Ji et al.
ELIFE (2014)
A Pharmacokinetic/Pharmacodynamic Model of Tumor Lysis Syndrome in Chronic Lymphocytic Leukemia Patients Treated with Flavopiridol
Jia Ji et al.
CLINICAL CANCER RESEARCH (2013)
Cdks, cyclins and CKIs: roles beyond cell cycle regulation
Shuhui Lim et al.
DEVELOPMENT (2013)
Inhibition of metastasis by HEXIM1 through effects on cell invasion and angiogenesis
W. Ketchart et al.
ONCOGENE (2013)
The monocrotaline model of pulmonary hypertension in perspective
Jose G. Gomez-Arroyo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
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Cristian Moiola et al.
CELL CYCLE (2010)
Flavopiridol, the First Cyclin-Dependent Kinase Inhibitor: Recent Advances in Combination Chemotherapy
L. -M. Wang et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2010)
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M. Kathryn Steiner et al.
CIRCULATION RESEARCH (2009)
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
MS McMurtry et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP
EH Kim et al.
ONCOGENE (2004)
Binding of the 7SK snRNA turns the HEXIM1 protein into a P-TEFb (CDK9/cyclin T) inhibitor
AA Michels et al.
EMBO JOURNAL (2004)
Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy
M Sano et al.
NATURE MEDICINE (2002)
c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanism
SR Eberhardy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Flavopiridol inhibits P-TEFb and blocks HIV-1 replication
SH Chao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)