4.7 Article

Impact of prediabetes and diabetes on 3-year outcome of patients treated with new-generation drug-eluting stents in two large-scale randomized clinical trials

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Treating diabetic all-comers with contemporary drug-eluting stents: Prespecified comparisons from the BIO-RESORT and the BIONYX randomized trials

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Summary: This study evaluated the 2-year clinical outcomes of diabetic patients treated with different contemporary drug-eluting stents (DES), showing no significant difference in patients with diabetes treated with Orsiro sirolimus-eluting stents (SES) or Synergy everolimus-eluting stents (EES) compared to Resolute Integrity zotarolimus-eluting stents (RI-ZES). Similarly, there was no difference in clinical outcomes in diabetic patients treated with SES versus Resolute Onyx zotarolimus-eluting stents (RO-ZES). These findings suggest the safety and efficacy of the studied DES in diabetic patients.

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