期刊
CARBOHYDRATE POLYMERS
卷 274, 期 -, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2021.118648
关键词
Sea buckthorn; Polysaccharides; Structure; Drosophila melanogaster; Antioxidant activity
资金
- National Natural Science Foundation of China [41406142]
- Natural Science Foundation of Zhejiang Province, China [LGF19D06004, LQ18D060005, LGN18D060002]
- Science and Technology Planning Project of Zhoushan of China [2019C21015]
A novel heteropolysaccharide fraction (SP0.1-1) was isolated from Sea buckthorn berries, with a specific composition and structure. Supplementing with SP0.1-1 extended fruit flies' lifespan, enhanced antioxidant enzyme activities, and reduced oxidative damage, showing potential for sea buckthorn polysaccharide products development.
The sea buckthorn (Hippophae rhamnoides L.) berries are rich in various bioactive components and widely used as fruit and traditional medicine. In this study, a novel heteropolysaccharide fraction (SP0.1-1) was isolated from Sea buckthorn berries. SP0.1-1 is composed of mannose, glucose, galactose, and arabinose in the molar ratio of 1:2.3:1.9:11.2 with a core structure containing 1,4-linked-alpha-D-Glcp, 1,4,6-linked-alpha-D-Glcp and 1,4-linked-alpha-DManp residues as the backbone. And the side-chains comprised of 1,3,5-linked-alpha-L-Araf, 1,5-linked-alpha-L-Araf, terminal alpha-Araf and 1,4-linked-beta-D-Galp. Furthermore, a diet supplemented with SP0.1-1 extended the mean lifespan, enhanced antioxidant enzyme (superoxide dismutase, SOD; glutathione peroxidase, GSH-Px; and catalase, CAT) activities, and decreased the malondialdehyde (MDA) level and hydrogen peroxide (H2O2)induced mortality rate in fruit flies (Drosophila melanogaster). To summarize, the study's findings will provide evidence for the development of sea buckthorn polysaccharide products.
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