Stretchable unidirectional liquid-transporting membrane with antibacterial and biocompatible features based on chitosan derivative and composite nanofibers

Unidirectional liquid transport is critical in achieving high-performance moisture-management fabrics for medical care. However, realizing unidirectional liquid transport while simultaneously satisfying other requirements, such as antibacterial function, adhesiveness, low cytotoxicity, and adequate mechanical strength remains a challenge. In this study, Janus nanofibrous membranes exhibiting both unidirectional liquid transport and antibacterial activity were fabricated via electrospinning and a mild crosslinking procedure. This membrane provides continuous and spontaneous unidirectional water transport with a high one-way transport value (R) of 1483%. The membrane achieved antibacterial rates of 99.2% and 98.7% against E. coli and S. aureus, respectively, without leaching antibacterial agents. In addition, it has high elasticity and self-adhesive properties, which facilitates its use in a range of applications. The design of this versatile Janus nanofibrous membrane provides a new strategy for developing novel moisture-wicking systems, particularly in the field of medical dressings.

Automated summary

This study fabricated Janus nanofibrous membranes with unidirectional liquid transport and antibacterial activity through electrospinning and mild crosslinking. The membrane shows high one-way transport value and antibacterial rates against E. coli and S. aureus without leaching antibacterial agents. Its high elasticity and self-adhesive properties make it suitable for various applications, offering a new strategy for developing novel moisture-wicking systems in medical dressings.