Chitin and derivative chitosan-based structures-Preparation strategies aided by deep eutectic solvents: A review

The high molecular weight of chitin, as a biopolymer, challenges its extraction due to its insolubility in the solvents. Also, chitosan, as the N-deacetylated form of chitin, can be employed as a primary material for different industries. The low mechanical stability and poor plasticity of chitosan films, as a result of incompatible interaction between chitosan and the used solvent, have limited its industrialization. Deep eutectic solvents (DESs), as novel solvents, can solve the extraction difficulties of chitin, and the low mechanical stability and weak plasticity of chitosan films. Also, DESs can be considered for the different chitosan and chitin productions, including chitin nanocrystal and nanofiber, N,N,N-trimethyl-chitosan, chitosan-based imprinted structures, and DES-chitosanbased beads and monoliths. This review aims to focus on the preparation and characterization (chemistry and morphology) of DES-chitin-based and DES-chitosan-based structures to understand the influence of the incorporation of DESs into the chitin and chitosan structure.

Automated summary

The high molecular weight of chitin poses challenges for its extraction due to solubility issues, while chitosan faces limitations in industrialization due to poor mechanical stability and plasticity of its films caused by incompatible solvent interactions. Deep eutectic solvents (DESs) offer a solution for these challenges, and show potential in various chitosan and chitin productions.