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Tyler J. Bussian et al.
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Mangoni Monica et al.
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Yi Zhu et al.
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C. Turnquist et al.
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Taemin Oh et al.
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Adam Freund et al.
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Barbara Sennino et al.
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The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data
Ethan Cerami et al.
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Michael V. Sofroniew et al.
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Jean-Philippe Coppe et al.
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Dan Liu et al.
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The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms
C Bavik et al.
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Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
R Abounader et al.
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KKC Tsai et al.
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R Stupp et al.
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S Parrinello et al.
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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
A Krtolica et al.
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