相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。The emerging roles of exosomes in anti-cancer drug resistance and tumor progression: An insight towards tumor-microenvironment interaction
Bikash Chandra Jena et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2021)
Single-cell RNA-seq dissects the intratumoral heterogeneity of triple-negative breast cancer based on gene regulatory networks
Shunheng Zhou et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2021)
Paracrine TGF-131 from breast cancer contributes to chemoresistance in cancer associated fibroblasts via upregulation of the p44/42 MAPK signaling pathway
Bikash Chandra Jena et al.
BIOCHEMICAL PHARMACOLOGY (2021)
Functional diversity of cancer-associated fibroblasts in modulating drug resistance
Luke Bu et al.
CANCER SCIENCE (2020)
Cancer-Associated Fibroblasts: Versatile Players in the Tumor Microenvironment
Debolina Ganguly et al.
CANCERS (2020)
Cancer associated fibroblast mediated chemoresistance: A paradigm shift in understanding the mechanism of tumor progression
Bikash Chandra Jena et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2020)
TGF-β Mediated Immune Evasion in Cancer-Spotlight on Cancer-Associated Fibroblasts
Parisa Ghahremanifard et al.
CANCERS (2020)
Transforming Growth Factor-β Signaling in Fibrotic Diseases and Cancer-Associated Fibroblasts
Xueke Shi et al.
BIOMOLECULES (2020)
Cancer-associated fibroblast-secreted exosomal miR-423-5p promotes chemotherapy resistance in prostate cancer by targeting GREM2 through the TGF-β signaling pathway
Guang Shan et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2020)
A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression
Francesca R. Auciello et al.
CANCER DISCOVERY (2019)
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
Yu Shi et al.
NATURE (2019)
Fibroblasts as Modulators of Local and Systemic Cancer Metabolism
Hannah Sanford-Crane et al.
CANCERS (2019)
Cancer-associated fibroblasts-derived IL-8 mediates resistance to cisplatin in human gastric cancer
Jing Zhai et al.
CANCER LETTERS (2019)
Integrin-Mediated TGFβ Activation Modulates the Tumour Microenvironment
Nicholas E. Brown et al.
CANCERS (2019)
Transforming Growth Factor-β Signaling Pathway in Colorectal Cancer and Its Tumor Microenvironment
Yoshiro Itatani et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy
Thomas Bertero et al.
CELL METABOLISM (2019)
Transforming growth factor-β signaling: Tumorigenesis and targeting for cancer therapy
Amirhossein Ahmadi et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2019)
Exosome as a Novel Shuttle for Delivery of Therapeutics across Biological Barriers
Chandan Kanta Das et al.
MOLECULAR PHARMACEUTICS (2019)
Turning foes to friends: targeting cancer-associated fibroblasts
Xueman Chen et al.
NATURE REVIEWS DRUG DISCOVERY (2019)
TGF signaling and the control of myofibroblast differentiation: Implications for chronic inflammatory disorders
Jonathon M. Carthy
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
IL6 derived from cancer-associated fibroblasts promotes chemoresistance via CXCR7 in esophageal squamous cell carcinoma
Y. Qiao et al.
ONCOGENE (2018)
TGF-beta requires the activation of canonical and non-canonical signalling pathways to induce skeletal muscle atrophy
Johanna Abrigo et al.
BIOLOGICAL CHEMISTRY (2018)
Tumor-Stroma IL1 beta-IRAK4 Feedforward Circuitry DrivesTumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer
Daoxiang Zhang et al.
CANCER RESEARCH (2018)
Thrombospondin-1 regulation of latent TGF-β activation: A therapeutic target for fibrotic disease
Joanne E. Murphy-Ullrich et al.
MATRIX BIOLOGY (2018)
Exosomes Induce Fibroblast Differentiation into Cancer-Associated Fibroblasts through TGFβ Signaling
Cassandra Ringuette Goulet et al.
MOLECULAR CANCER RESEARCH (2018)
TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
Daniele V. F. Tauriello et al.
NATURE (2018)
Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer
Yen-An Tang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer
Aurelie S. Cazet et al.
NATURE COMMUNICATIONS (2018)
TGF-β Sustains Tumor Progression through Biochemical and Mechanical Signal Transduction
Robert L. Furler et al.
CANCERS (2018)
TGF-β receptors: In and beyond TGF-β signaling
Alexandra Vander Ark et al.
CELLULAR SIGNALLING (2018)
Stromal Fibroblasts Mediate Anti-PD-1 Resistance via MMP-9 and Dictate TGF beta Inhibitor Sequencing in Melanoma
Fei Zhao et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Artemisinin derivatives inactivate cancer-associated fibroblasts through suppressing TGF- signaling in breast cancer
Yuyuan Yao et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2018)
Cytoplasmic GPER translocation in cancer-associated fibroblasts mediates cAMP/PKA/CREB/glycolytic axis to confer tumor cells with multidrug resistance
T. Yu et al.
ONCOGENE (2017)
Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells
K. E. Richards et al.
ONCOGENE (2017)
Non-Smad Signaling Pathways of the TGF-β Family
Ying E. Zhang
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2017)
Activation of Transforming Growth Factor Beta 1 Signaling in Gastric Cancer-associated Fibroblasts Increases Their Motility, via Expression of Rhomboid 5 Homolog 2, and Ability to Induce Invasiveness of Gastric Cancer Cells
Takatsugu Ishimoto et al.
GASTROENTEROLOGY (2017)
Epithelial-to-mesenchymal transition transcription factors in cancer-associated fibroblasts
Josep Baulida
MOLECULAR ONCOLOGY (2017)
Stem cells in cancer therapy: opportunities and challenges
Cheng-Liang Zhang et al.
ONCOTARGET (2017)
Epithelial-mesenchymal transition as a therapeutic target for overcoming chemoresistance in pancreatic cancer
Omar Elaskalani et al.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY (2017)
TGF-β-Induced Quiescence Mediates Chemoresistance of Tumor-Propagating Cells in Squamous Cell Carcinoma
Jessie A. Brown et al.
CELL STEM CELL (2017)
Cancer-associated fibroblasts modulate growth factor signaling and extracellular matrix remodeling to regulate tumor metastasis
Begum Erdogan et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2017)
Dichotomous roles of TGF-β in human cancer
Jennifer J. Huang et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2016)
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
Christopher J. Tape et al.
CELL (2016)
The role of integrins in TGFβ activation in the tumour stroma
Zareen Khan et al.
CELL AND TISSUE RESEARCH (2016)
Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion
T. T. Vellinga et al.
ONCOGENE (2016)
SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment
Y. Sun et al.
ONCOGENE (2016)
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih-Hao Chang et al.
CELL (2015)
Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness andmetastasis
Chris D. Madsen et al.
EMBO REPORTS (2015)
Co-culture of 3D tumor spheroids with fibroblasts as a model for epithelial-mesenchymal transition in vitro
Sun-Ah Kim et al.
EXPERIMENTAL CELL RESEARCH (2015)
Expression of cancer-associated fibroblast related proteins in metastatic breast cancer: an immunohistochemical analysis
Hye Min Kim et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Transforming Growth Factor Beta Family: Insight into the Role of Growth Factors in Regulation of Fracture Healing Biology and Potential Clinical Applications
Lukasz A. Poniatowski et al.
MEDIATORS OF INFLAMMATION (2015)
Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
Alexandre Calon et al.
NATURE GENETICS (2015)
TGFβ1 secreted by cancer-associated fibroblasts induces epithelial-mesenchymal transition of bladder cancer cells through lncRNA-ZEB2NAT
Junlong Zhuang et al.
SCIENTIFIC REPORTS (2015)
Tumors: Wounds That Do Not Heal-Redux
Harold F. Dvorak
CANCER IMMUNOLOGY RESEARCH (2015)
IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction
C. Rupp et al.
ONCOGENE (2015)
Cancer-associated fibroblasts induce epithelial-mesenchymal transition of breast cancer cells through paracrine TGF-β signalling
Y. Yu et al.
BRITISH JOURNAL OF CANCER (2014)
Metabolic Reprogramming of Stromal Fibroblasts through p62-mTORC1 Signaling Promotes Inflammation and Tumorigenesis
Tania Valencia et al.
CANCER CELL (2014)
VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation
Anna Fantozzi et al.
CANCER RESEARCH (2014)
Collective migration of cancer-associated fibroblasts is enhanced by overexpression of tight junction-associated proteins daudin-11 and occludin
George S. Karagiannis et al.
MOLECULAR ONCOLOGY (2014)
Interaction with colon cancer cells hyperactivates TGF-beta signaling in cancer-associated fibroblasts
L. J. A. C. Hawinkels et al.
ONCOGENE (2014)
CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma
A. Shukla et al.
ONCOGENE (2014)
Prognostic significance of Zinc finger E-box binding homeobox 1 (ZEB1) expression in cancer cells and cancer-associated fibroblasts in pancreatic head cancer
Peter Bronsert et al.
SURGERY (2014)
Transforming Growth Factor-Beta and Matrix Metalloproteinases: Functional Interactions in Tumor Stroma-Infiltrating Myeloid Cells
Jelena Krstic et al.
SCIENTIFIC WORLD JOURNAL (2014)
The Carcinoma-Associated Fibroblast Expressing Fibroblast Activation Protein and Escape from Immune Surveillance
Douglas T. Fearon
CANCER IMMUNOLOGY RESEARCH (2014)
Roles of Matrix Metalloproteinases and Their Natural Inhibitors in Prostate Cancer Progression
Yixuan Gong et al.
CANCERS (2014)
Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood
Lesley Cheng et al.
JOURNAL OF EXTRACELLULAR VESICLES (2014)
Identification of Two Distinct Carcinoma-Associated Fibroblast Subtypes with Differential Tumor-Promoting Abilities in Oral Squamous Cell Carcinoma
Daniela Elena Costea et al.
CANCER RESEARCH (2013)
Autophagic tumor stroma: Mechanisms and roles in tumor growth and progression
Xianda Zhao et al.
INTERNATIONAL JOURNAL OF CANCER (2013)
Breast Fibroblasts Modulate Early Dissemination, Tumorigenesis, and Metastasis through Alteration of Extracellular Matrix Characteristics
Nancy Dumont et al.
NEOPLASIA (2013)
Beyond TGFβ: roles of other TGFβ superfamily members in cancer
Lalage M. Wakefield et al.
NATURE REVIEWS CANCER (2013)
Bone Marrow-Derived Mesenchymal Stem Cells Differentiate to Hepatic Myofibroblasts by Transforming Growth Factor-β1 via Sphingosine Kinase/Sphingosine 1-Phosphate (S1P)/S1P Receptor Axis
Le Yang et al.
AMERICAN JOURNAL OF PATHOLOGY (2012)
Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation
Alexandre Calon et al.
CANCER CELL (2012)
Metabolic remodeling of the tumor microenvironment Migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth
Valentina Carito et al.
CELL CYCLE (2012)
CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth
Claudia Capparelli et al.
CELL CYCLE (2012)
Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production
Claudia Capparelli et al.
CELL CYCLE (2012)
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, fueling tumor growth via paracrine interactions, without an increase in neo-angiogenesis
Claudia Capparelli et al.
CELL CYCLE (2012)
Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth Connecting TGF-β signaling with Warburg-like cancer metabolism and L-lactate production
Carmela Guido et al.
CELL CYCLE (2012)
Targeting the TGFβ signalling pathway in disease
Rosemary J. Akhurst et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Inhibition of TGF-β/Smad Signaling by BAMBI Blocks Differentiation of Human Mesenchymal Stem Cells to Carcinoma-Associated Fibroblasts and Abolishes Their Protumor Effects
Lei Shangguan et al.
STEM CELLS (2012)
CD36 Repression Activates a Multicellular Stromal Program Shared by High Mammographic Density and Tumor Tissues
Rosa Anna DeFilippis et al.
CANCER DISCOVERY (2012)
The Role of TGF beta Signaling in Squamous Cell Cancer: Lessons from Mouse Models
Adam B. Glick
JOURNAL OF SKIN CANCER (2012)
Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis
Jacky G. Goetz et al.
CELL (2011)
Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
Chrisostomi Gialeli et al.
FEBS JOURNAL (2011)
Exploring anti-TGF-ββ therapies in cancer and fibrosis
Lukas J. A. C. Hawinkels et al.
GROWTH FACTORS (2011)
Latent TGF-β structure and activation
Minlong Shi et al.
NATURE (2011)
Adipose tissue derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor derived factors
Constantin Jotzu et al.
CELLULAR ONCOLOGY (2011)
A chemical biology screen reveals a role for Rab21-mediated control of actomyosin contractility in fibroblast-driven cancer invasion
S. Hooper et al.
BRITISH JOURNAL OF CANCER (2010)
Breast Carcinoma-Associated Fibroblasts Rarely Contain p53 Mutations or Chromosomal Aberrations
Abdel Nasser Hosein et al.
CANCER RESEARCH (2010)
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
Kai Kessenbrock et al.
CELL (2010)
The autophagic tumor stroma model of cancer or battery-operated tumor growth A simple solution to the autophagy paradox
Ubaldo E. Martinez-Outschoorn et al.
CELL CYCLE (2010)
Down-Regulation of Connective Tissue Growth Factor by Inhibition of Transforming Growth Factor β Blocks the Tumor-Stroma Cross-Talk and Tumor Progression in Hepatocellular Carcinoma
Antonio Mazzocca et al.
HEPATOLOGY (2010)
Mesenchymal stem cells enhance growth and metastasis of colon cancer
Kei Shinagawa et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
Louis Vermeulen et al.
NATURE CELL BIOLOGY (2010)
Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts
Yasushi Kojima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein-α
Matthew Kraman et al.
SCIENCE (2010)
Ski and SnoN, potent negative regulators of TGF-beta signaling
Julien Deheuninck et al.
CELL RESEARCH (2009)
Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression
Erika L. Spaeth et al.
PLOS ONE (2009)
Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer
Kenneth P. Olive et al.
SCIENCE (2009)
Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging
Hui Wang et al.
STEM CELLS (2009)
Direct Evidence of Mesenchymal Stem Cell Tropism for Tumor and Wounding Microenvironments Using In Vivo Bioluminescent Imaging
Shannon Kidd et al.
STEM CELLS (2009)
Environment-mediated drug resistance: a major contributor to minimal residual disease
Mark B. Meads et al.
NATURE REVIEWS CANCER (2009)
MT1-MMP releases latent TGF-β1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1
Olga Tatti et al.
EXPERIMENTAL CELL RESEARCH (2008)
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas
Wen Qiu et al.
NATURE GENETICS (2008)
Differentiation plasticity regulated by TGF-β family proteins in development and disease
Rik Derynck et al.
NATURE CELL BIOLOGY (2007)
Cross-talk between paracrine-acting cytokine and chemokine pathways promotes malignancy in benign human prostatic
Mingfang Ao et al.
CANCER RESEARCH (2007)
Identification of fibroblast heterogeneity in the tumor microenvironment
Hikaru Sugimoto et al.
CANCER BIOLOGY & THERAPY (2006)
BMP1 controls TGFβ1 activation via cleavage of latent TGFβ-binding protein protein
Gaoxiang Ge et al.
JOURNAL OF CELL BIOLOGY (2006)
Increased expression of integrin αvβ3 contributes to the establishment of autocrine TGF-β signaling in scleroderma fibroblasts
Y Asano et al.
JOURNAL OF IMMUNOLOGY (2005)
TGF-β1 attenuates the acquisition and expression of effector function by tumor antigen-specific human memory CD8 T cells
M Ahmadzadeh et al.
JOURNAL OF IMMUNOLOGY (2005)
Combined total genome loss of heterozygosity scan of breast cancer stroma and epithelium reveals multiplicity of stromal targets
K Fukino et al.
CANCER RESEARCH (2004)
Epithelial to mesenchymal transition in human breast cancer can provide a nonmalignant stroma
OW Petersen et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
TGF-β1-mediated fibroblast-myofibroblast terminal differentiation -: the role of Smad proteins
RA Evans et al.
EXPERIMENTAL CELL RESEARCH (2003)
Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
PM Siegel et al.
NATURE REVIEWS CANCER (2003)
Metastasis is driven by sequential elevation of H-ras and Smad2 levels
M Oft et al.
NATURE CELL BIOLOGY (2002)
The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP-dependent activation of TGF-β1
DZ Mu et al.
JOURNAL OF CELL BIOLOGY (2002)
Genetic model of multi-step breast carcinogenesis involving the epithelium and stroma: clues to tumour-microenvironment interactions
K Kurose et al.
HUMAN MOLECULAR GENETICS (2001)