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Jiachi Ma et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)
PI3K Signaling Maintains c-myc Expression to Regulate Transcription of E2F1 in Pancreatic Cancer Cells
Carolin Schild et al.
MOLECULAR CARCINOGENESIS (2009)
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
Ping Gao et al.
NATURE (2009)
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
Tsung-Cheng Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Modelling Myc inhibition as a cancer therapy
Laura Soucek et al.
NATURE (2008)
HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α
Zoltan Arany et al.
NATURE (2008)
c-myc repression of TSC2 contributes to control of translation initiation and myc-induced transformation
Michael J. Ravitz et al.
CANCER RESEARCH (2007)
Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis
Tao Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-κB-regulated gene products
Ajaikumar B. Kunnumakkara et al.
CANCER RESEARCH (2007)
Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway
Malte Buchholz et al.
EMBO JOURNAL (2006)
Protein phosphatase 2A regulatory subunit b56α associates with c-Myc and negatively regulates c-Myc accumulation
HK Arnold et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
Michael Dews et al.
NATURE GENETICS (2006)
Secrets of a double agent: CDK7 in cell-cycle control and transcription
RP Fisher
JOURNAL OF CELL SCIENCE (2005)
β-catenin up-regulates the expression of cyclinD1, c-myc and MMP-7 in human pancreatic cancer: Relationships with carcinogenesis and metastasis
Yu-Jun Li et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2005)
The PI 3-kinase/Akt signaling pathway is activated due to aberrant Pten expression and targets transcription factors NF-κB and c-Myc in pancreatic cancer cells
T Asano et al.
ONCOGENE (2004)
Role of angiogenesis in tumor growth and metastasis
J Folkman
SEMINARS IN ONCOLOGY (2002)
c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression
TA Baudino et al.
GENES & DEVELOPMENT (2002)
c-MYC activation in primary and metastatic ductal adenocarcinoma of the pancreas: Incidence, mechanisms, and clinical significance
C Schleger et al.
MODERN PATHOLOGY (2002)
Translocations involving c-myc and c-myc function
LM Boxer et al.
ONCOGENE (2001)
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