Association between tracheostomy timing and outcomes for older critically ill COVID-19 patients: prospective observational study in European intensive care units

Letter Cardiac & Cardiovascular Systems

Inhibitors of the renin-angiotensin-aldosterone system and COVID-19 in critically ill elderly patients

Christian Jung et al.

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY (2021)

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Review Otorhinolaryngology

Assessment of the harms and potential benefits of tracheostomy in COVID-19 patients: Narrative review of outcomes and recommendations

Ahmad Al Omari et al.

AMERICAN JOURNAL OF OTOLARYNGOLOGY (2021)

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Review Multidisciplinary Sciences

Population risk factors for severe disease and mortality in COVID-19: A global systematic review and meta-analysis

Adam Booth et al.

Summary: The study aims to analyze various clinical, demographic, and lifestyle variables associated with specific adverse outcomes in COVID-19 patients; by combining data from 17,860,001 patients across 14 countries, it identified many risk factors related to COVID-19, including age over 75, male sex, severe obesity, and active cancer.

PLOS ONE (2021)

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Review Dentistry, Oral Surgery & Medicine

Systematic review and meta-analysis of tracheostomy outcomes in COVID-19 patients

A. Ferro et al.

Summary: The systematic review and meta-analysis of COVID-19 tracheostomy patients aimed to determine the incidence of complications, mortality, time to decannulation and ventilatory weaning. The analysis found that a majority of patients were weaned from mechanical ventilation, while the cumulative mortality rate was around 19%. There was no significant difference in outcomes between surgical and percutaneous tracheostomy, as well as between early and late tracheostomy timing.

BRITISH JOURNAL OF ORAL & MAXILLOFACIAL SURGERY (2021)

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Review Otorhinolaryngology

Association of Tracheostomy With Outcomes in Patients With COVID-19 and SARS-CoV-2 Transmission Among Health Care Professionals A Systematic Review and Meta-analysis

Phillip Staibano et al.

Summary: This study evaluated the association of tracheostomy with outcomes in COVID-19 patients and the risk of SARS-CoV-2 transmission among healthcare professionals. Early tracheostomy may reduce ICU stay in COVID-19 patients, but the observational nature of the included studies limits the findings.

JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY (2021)

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Review Otorhinolaryngology

Tracheostomy During the COVID-19 Pandemic: Comparison of International Perioperative Care Protocols and Practices in 26 Countries

Carol Bier-Laning et al.

Summary: Tracheostomy protocols for COVID-19 patients vary widely worldwide, with most recommending at least 14 days of intubation before the procedure and negative COVID-19 test results prior to tracheostomy. The use of N95 or higher PPE is universal, with both open and percutaneous techniques reported. Timing of tracheostomy changes postoperatively range from 5 to over 30 days, sometimes conditional on negative COVID-19 test results.

OTOLARYNGOLOGY-HEAD AND NECK SURGERY (2021)

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Article Critical Care Medicine

The impact of frailty on survival in elderly intensive care patients with COVID-19: the COVIP study

Christian Jung et al.

Summary: This study aimed to determine the interaction of frailty and age in elderly COVID-19 ICU patients, finding that frailty was independently associated with lower survival rates. Frail patients were more likely to have treatment limitations and less likely to receive mechanical ventilation.

CRITICAL CARE (2021)

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Editorial Material Medicine, General & Internal