Bacterial co-infections in community-acquired pneumonia caused by SARS-CoV-2, influenza virus and respiratory syncytial virus

Article Infectious Diseases

Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study

Carolina Garcia-Vidal et al.

Summary: The study found that co-infections and superinfections in hospitalized COVID-19 patients were relatively low compared to other viral pandemics. Patients experienced worse outcomes after hospital-acquired superinfections occurred.

CLINICAL MICROBIOLOGY AND INFECTION (2021)

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Article Infectious Diseases

Exclusion of bacterial co-infection in COVID-19 using baseline inflammatory markers and their response to antibiotics

Claire Y. Mason et al.

Summary: This study found that patients with community-acquired pneumonia (CAP) had higher baseline white cell counts and C-reactive protein levels, as well as a greater decrease in CRP upon hospital admission compared to COVID-19 patients. A multivariate logistic regression model incorporating WCC and CRP changes could distinguish bacterial co-infection and differentiate between CAP and COVID-19.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2021)

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Article Public, Environmental & Occupational Health

Short Report Evaluation of procalcitonin as a contribution to antimicrobial stewardship in SARS-CoV-2 infection: a retrospective cohort study

E. J. Williams et al.

Summary: This study evaluated the effectiveness of a guideline recommending withholding antibiotics in coronavirus disease patients with low serum procalcitonin levels, showing reduced antibiotic consumption without increased mortality. Further research to determine the optimal cut-off value for procalcitonin is recommended.

JOURNAL OF HOSPITAL INFECTION (2021)

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Article Infectious Diseases

Community-acquired bacteraemia in COVID-19 in comparison to influenza A and influenza B: a retrospective cohort study

Julinha M. Thelen et al.

Summary: A study in the Netherlands found a very low occurrence of community-acquired bacteremia in COVID-19 patients compared to influenza patients, suggesting that antibiotics should only be used in COVID-19 patients when bacterial co-infection is suspected.

BMC INFECTIOUS DISEASES (2021)

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Letter Medicine, General & Internal