4.8 Article

Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biology

Enhanced hepatic respiratory capacity and altered lipid metabolism support metabolic homeostasis during short-term hypoxic stress

Katie A. O'Brien et al.

Summary: Short-term exposure to hypoxia enhances hepatic respiratory capacity and alters lipid metabolism, but these changes are transient and resolved after 14 days. These findings may have implications in understanding and treating hepatic pathologies associated with hypoxia.

BMC BIOLOGY (2021)

Article Biochemistry & Molecular Biology

Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness

Helen T. McKenna et al.

Summary: This study demonstrates rapid, specific and coordinated changes in cellular respiratory machinery, intermediary metabolism, and redox response in critically ill patients, with different trajectories in survivors and non-survivors. Differences in survival rates and metabolic activities were observed between survivors and non-survivors at 48 hours and day 7. Increases in oxidative stress and reductive drive were evident in critically ill patients, with non-survivors showing greater oxidative pressure and vascular inflammation compared to survivors.

REDOX BIOLOGY (2021)

Article Biochemistry & Molecular Biology

MetaboLights: a resource evolving in response to the needs of its scientific community

Kenneth Haug et al.

NUCLEIC ACIDS RESEARCH (2020)

Review Cell Biology

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

Pearl Lee et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Medicine, General & Internal

Effects of Germline VHL Deficiency on Growth, Metabolism, and Mitochondria

Silverio Perrotta et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Article Genetics & Heredity

Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice

Alice P. Sowton et al.

MOLECULAR GENETICS AND METABOLISM REPORTS (2020)

Article Multidisciplinary Sciences

Na+controls hypoxic signalling by the mitochondrial respiratory chain

Pablo Hernansanz-Agustin et al.

NATURE (2020)

Review Biochemistry & Molecular Biology

PPARα-independent effects of nitrate supplementation on skeletal muscle metabolism in hypoxia

Katie A. O'Brien et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2019)

Article Multidisciplinary Sciences

Noncanonical mitochondrial unfolded protein response impairs placental oxidative phosphorylation in early-onset preeclampsia

Hong Wa Yung et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Review Critical Care Medicine

Obstructive Sleep Apnea, Hypoxia, and Nonalcoholic Fatty Liver Disease

Omar A. Mesarwi et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2019)

Review Biochemistry & Molecular Biology

Exploring the molecular interface between hypoxia-inducible factor signalling and mitochondria

Luke W. Thomas et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2019)

Article Biochemistry & Molecular Biology

MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis

Jasmine Chong et al.

NUCLEIC ACIDS RESEARCH (2018)

Article Biotechnology & Applied Microbiology

Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption

Francis W. B. Sanders et al.

GENOME BIOLOGY (2018)

Article Multidisciplinary Sciences

Metabolic basis to Sherpa altitude adaptation

James A. Horscroft et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Biochemistry & Molecular Biology

Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia

Pablo Hernansanz-Agustin et al.

REDOX BIOLOGY (2017)

Article Endocrinology & Metabolism

Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity

Rainey E. Patterson et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2016)

Article Gastroenterology & Hepatology

Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

Alexandra Montagner et al.

Article Medicine, Research & Experimental

Effects of acute hypoxia on human adipose tissue lipoprotein lipase activity and lipolysis

Bimit Mahat et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2016)

Article Multidisciplinary Sciences

Mechanism of super-assembly of respiratory complexes III and IV

Sara Cogliati et al.

NATURE (2016)

Article Medicine, Research & Experimental

Hypoxia is associated with a lower expression of genes involved in lipogenesis in visceral adipose tissue

Eduardo Garcia-Fuentes et al.

JOURNAL OF TRANSLATIONAL MEDICINE (2015)

Article Multidisciplinary Sciences

Antimalarial 4(1H)-pyridones bind to the Qi site of cytochrome bc1

Michael J. Capper et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Higd1a is a positive regulator of cytochrome c oxidase

Takaharu Hayashi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Biochemistry & Molecular Biology

Impact of high altitude on the hepatic fatty acid oxidation and synthesis in rats

Qian Ni et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)

Review Biochemistry & Molecular Biology

The function of the respiratory supercomplexes: The plasticity model

Rebeca Acin-Perez et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2014)

Article Biochemistry & Molecular Biology

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

David A. Patten et al.

EMBO JOURNAL (2014)

Article Gastroenterology & Hepatology

Hypoxia and fatty liver

Tomohiro Suzuki et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Article Multidisciplinary Sciences

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

Jurre J. Kamphorst et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Higd-1a interacts with Opa1 and is required for the morphological and functional integrity of mitochondria

Hyun-Jung An et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain

Esther Lapuente-Brun et al.

SCIENCE (2013)

Review Biochemistry & Molecular Biology

Hypoxia-Inducible Factors in Physiology and Medicine

Gregg L. Semenza

Article Biochemistry & Molecular Biology

Calorie restriction increases cerebral mitochondrial respiratory capacity in a NO•-mediated mechanism: Impact on neuronal survival

Fernanda M. Cerqueira et al.

FREE RADICAL BIOLOGY AND MEDICINE (2012)

Article Gastroenterology & Hepatology

HIF-1α induction suppresses excessive lipid accumulation in alcoholic fatty liver in mice

Yasumasa Nishiyama et al.

JOURNAL OF HEPATOLOGY (2012)

Article Neurosciences

Biomarkers of mitochondrial content in skeletal muscle of healthy young human subjects

Steen Larsen et al.

JOURNAL OF PHYSIOLOGY-LONDON (2012)

Article Biochemical Research Methods

NIH Image to ImageJ: 25 years of image analysis

Caroline A. Schneider et al.

NATURE METHODS (2012)

Review Biochemistry & Molecular Biology

Passing the baton: the HIF switch

Mei Yee Koh et al.

TRENDS IN BIOCHEMICAL SCIENCES (2012)

Article Biochemistry & Molecular Biology

The survival effect of mitochondrial Higd-1a is associated with suppression of cytochrome C release and prevention of caspase activation

Hyun-Jung An et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)

Review Cell Biology

Making heads or tails of phospholipids in mitochondria

Christof Osman et al.

JOURNAL OF CELL BIOLOGY (2011)

Review Spectroscopy

MASS SPECTROMETRIC ANALYSIS OF LONG-CHAIN LIPIDS

Robert C. Murphy et al.

MASS SPECTROMETRY REVIEWS (2011)

Article Endocrinology & Metabolism

Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates

Matthew D. Bruss et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)

Article Endocrinology & Metabolism

Reduced Oxygenation in Human Obese Adipose Tissue Is Associated with Impaired Insulin Suppression of Lipolysis

Magdalena Pasarica et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2010)

Article Multidisciplinary Sciences

Regulation of human metabolism by hypoxia-inducible factor

Federico Formenti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Review Biochemistry & Molecular Biology

The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice

Herve Guillou et al.

PROGRESS IN LIPID RESEARCH (2010)

Article Biochemistry & Molecular Biology

Hypoxia-Inducible Factor 2 Regulates Hepatic Lipid Metabolism

Erinn B. Rankin et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Gastroenterology & Hepatology

Chronic intermittent hypoxia causes hepatitis in a mouse model of diet-induced fatty liver

Vladimir Savransky et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)

Article Biochemistry & Molecular Biology

LIPID MAPS online tools for lipid research

Eoin Fahy et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Physiology

Alterations in enzymes involved in fat metabolism after acute and chronic altitude exposure

SL Kennedy et al.

JOURNAL OF APPLIED PHYSIOLOGY (2001)