The gut-bone marrow axis a novel player in HSC aging Comment

The microbiota is attracting increasing attention for its role in affecting hematopoiesis. In this issue of Blood, Kovtonyuk et al describe the role of the microbiome-IL1 axis as a key, self-sustaining, but reversible driver of hematopoietic stem cell (HSC) inflammaging.(1)

Automated summary

This article describes the role of the microbiome-IL1 axis as a key, self-sustaining, but reversible driver of hematopoietic stem cell inflammaging.