Adult T-cell leukemia: genomic analysis Comment

In this issue of Blood, Kogure et al,(1) by a whole-genome analysis of 150 cases of adult T-cell leukemia/lymphoma (ATL), identify new oncogenic driv-ers, noncoding and structural mutations, and a novel molecular signature that distinguishes the leukemic from the lymphomatous forms.

Automated summary

In this study, Kogure et al identify new oncogenic drivers, noncoding and structural mutations, and a novel molecular signature that distinguishes the leukemic from the lymphomatous forms of adult T-cell leukemia/lymphoma (ATL) through a whole-genome analysis of 150 cases.