4.7 Editorial Material

CNS prophylaxis in DLBCL time to say goodbye?

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Article Hematology

Single-route CNS prophylaxis for aggressive non-Hodgkin lymphomas: real-world outcomes from 21 US academic institutions

Victor Manuel Orellana-Noia et al.

Summary: This study on CNS prophylaxis in DLBCL patients found no significant difference in CNS relapse rates between different routes of administration. However, relapse rates remain elevated in high-risk subgroups, highlighting the need for reevaluation of prophylaxis strategies.