The study demonstrated that an optimal benefit-to-risk outcome for patients with chronic myeloid leukemia who had failed prior therapy was to start with a dose of 45 mg of ponatinib, which could then be reduced to 15 mg upon attainment of a response.
In this issue of Blood, Cortes et al demonstrate that the optimal benefit-to-risk outcome for ponatinib-treated patients with chronic myeloid leukemia (CML) who had failed prior therapy was a starting dose of 45 mg, which was reduced to 15 mg upon attainment of a response.
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