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MICROBIAL CELL FACTORIES (2013)
Heterologous Reconstitution of the Intact Geodin Gene Cluster in Aspergillus nidulans through a Simple and Versatile PCR Based Approach
Morten Thrane Nielsen et al.
PLOS ONE (2013)
One pathway, many compounds: heterologous expression of a fungal biosynthetic pathway reveals its intrinsic potential for diversity
Zahida Wasil et al.
CHEMICAL SCIENCE (2013)
Discovery of Cryptic Polyketide Metabolites from Dermatophytes Using Heterologous Expression in Aspergillus nidulans
Wen-Bing Yin et al.
ACS SYNTHETIC BIOLOGY (2013)
Heterologous expression system in Aspergillus oryzae for fungal biosynthetic gene clusters of secondary metabolites
Kanae Sakai et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2012)
Establishing a New Methodology for Genome Mining and Biosynthesis of Polyketides and Peptides through Yeast Molecular Genetics
Kan'ichiro Ishiuchi et al.
CHEMBIOCHEM (2012)
Advancing secondary metabolite biosynthesis in yeast with synthetic biology tools
Michael S. Siddiqui et al.
FEMS YEAST RESEARCH (2012)
Synthetic scaffolds increased resveratrol biosynthesis in engineered yeast cells
Yechun Wang et al.
JOURNAL OF BIOTECHNOLOGY (2012)
Proteomic and Biochemical Evidence Support a Role for Transport Vesicles and Endosomes in Stress Response and Secondary Metabolism in Aspergillus parasiticus
John E. Linz et al.
JOURNAL OF PROTEOME RESEARCH (2012)
Discovery and Characterization of a Group of Fungal Polycyclic Polyketide Prenyltransferases
Yit-Heng Chooi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Identification and Characterization of the Chaetoviridin and Chaetomugilin Gene Cluster in Chaetomium globosum Reveal Dual Functions of an Iterative Highly-Reducing Polyketide Synthase
Jaclyn M. Winter et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Identification and Characterization of the Echinocandin B Biosynthetic Gene Cluster from Emericella rugulosa NRRL 11440
Ralph A. Cacho et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
A fungal ketoreductase domain that displays substrate-dependent stereospecificity
Hui Zhou et al.
NATURE CHEMICAL BIOLOGY (2012)
Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain
Xue Gao et al.
NATURE CHEMICAL BIOLOGY (2012)
How Peroxisomes Affect Aflatoxin Biosynthesis in Aspergillus Flavus
Massimo Reverberi et al.
PLOS ONE (2012)
THE FUNGI: 1, 2, 3 ... 5.1 MILLION SPECIES?
Meredith Blackwell
AMERICAN JOURNAL OF BOTANY (2011)
Transformation System for Hypocrea jecorina (Trichoderma reesei) That Favors Homologous Integration and Employs Reusable Bidirectionally Selectable Markers
Matthias G. Steiger et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Versatile Enzyme Expression and Characterization System for Aspergillus nidulans, with the Penicillium brevicompactum Polyketide Synthase Gene from the Mycophenolic Acid Gene Cluster as a Test Case
Bjarne G. Hansen et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Fungal Gene Expression on Demand: an Inducible, Tunable, and Metabolism-Independent Expression System for Aspergillus niger
Vera Meyer et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)
Unraveling Terminal C-Domain-Mediated Condensation in Fungal Biosynthesis of Imidazoindolone Metabolites
Stuart W. Haynes et al.
BIOCHEMISTRY (2011)
Total Biosynthesis of Diterpene Aphidicolin, a Specific Inhibitor of DNA Polymerase α: Heterologous Expression of Four Biosynthetic Genes in Aspergillus oryzae
Ryuya Fujii et al.
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY (2011)
The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi
Magdalena Bartoszewska et al.
BIOTECHNOLOGY LETTERS (2011)
Peroxisome biogenesis: recent advances
James M. Nuttall et al.
CURRENT OPINION IN CELL BIOLOGY (2011)
Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms
Yi-Ming Chiang et al.
CURRENT OPINION IN CHEMICAL BIOLOGY (2011)
Compartmentalization and molecular traffic in secondary metabolism: A new understanding of established cellular processes
Ludmila V. Roze et al.
FUNGAL GENETICS AND BIOLOGY (2011)
Rational Domain Swaps Decipher Programming in Fungal Highly Reducing Polyketide Synthases and Resurrect an Extinct Metabolite
Katja M. Fisch et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
Comparative Characterization of Fungal Anthracenone and Naphthacenedione Biosynthetic Pathways Reveals an α-Hydroxylation-Dependent Claisen-like Cyclization Catalyzed by a Dimanganese Thioesterase
Yanran Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
A Fungal Nonribosomal Peptide Synthetase Module that can Synthesize Thiopyrazines
Kangjian Qiao et al.
ORGANIC LETTERS (2011)
Bacteria-induced natural product formation in the fungus Aspergillus nidulans requires Saga/Ada-mediated histone acetylation
Hans-Wilhelm Nuetzmann et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Engineered polyketide biosynthesis and biocatalysis in Escherichia coli
Xue Gao et al.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)
First Heterologous Reconstruction of a Complete Functional Fungal Biosynthetic Multigene Cluster
Mary N. Heneghan et al.
CHEMBIOCHEM (2010)
Intracellular Acetyl Unit Transport in Fungal Carbon Metabolism
Karin Strijbis et al.
EUKARYOTIC CELL (2010)
Peroxisomes as dynamic organelles: peroxisome abundance in yeast
Ruchi Saraya et al.
FEBS JOURNAL (2010)
Identification and characterization of genes responsible for biosynthesis of kojic acid, an industrially important compound from Aspergillus oryzae
Yasunobu Terabayashi et al.
FUNGAL GENETICS AND BIOLOGY (2010)
SMURF: Genomic mapping of fungal secondary metabolite clusters
Nora Khaldi et al.
FUNGAL GENETICS AND BIOLOGY (2010)
Aspernidine A and B, prenylated isoindolinone alkaloids from the model fungus Aspergillus nidulans
Kirstin Scherlach et al.
JOURNAL OF ANTIBIOTICS (2010)
Enzymatic Synthesis of Resorcylic Acid Lactones by Cooperation of Fungal Iterative Polyketide Synthases Involved in Hypothemycin Biosynthesis
Hui Zhou et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Analysis of Intact and Dissected Fungal Polyketide Synthase-Nonribosomal Peptide Synthetase in Vitro and in Saccharomyces cerevisiae
Wei Xu et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Reconstitution of a fungal meroterpenoid biosynthesis reveals the involvement of a novel family of terpene cyclases
Takayuki Itoh et al.
NATURE CHEMISTRY (2010)
Determination of the extent of phosphopantetheinylation of polyketide synthases expressed in Escherichia coli and Saccharomyces cerevisiae
Ka Kit Michael Lee et al.
ANALYTICAL BIOCHEMISTRY (2009)
A Thioesterase from an Iterative Fungal Polyketide Synthase Shows Macrocyclization and Cross Coupling Activity and May Play a Role in Controlling Iterative Cycling through Product Offloading
Meng Wang et al.
BIOCHEMISTRY (2009)
Developing Aspergillus as a host for heterologous expression
David Lubertozzi et al.
BIOTECHNOLOGY ADVANCES (2009)
Rational Improvement of Simvastatin Synthase Solubility in Escherichia coli Leads to Higher Whole-Cell Biocatalytic Activity
Xinkai Xie et al.
BIOTECHNOLOGY AND BIOENGINEERING (2009)
Directed Evolution and Structural Characterization of a Simvastatin Synthase
Xue Gao et al.
CHEMISTRY & BIOLOGY (2009)
Contribution of Peroxisomes to Penicillin Biosynthesis in Aspergillus nidulans
Petra Sproete et al.
EUKARYOTIC CELL (2009)
Proteins involved in microbody biogenesis and degradation in Aspergillus nidulans
Jan A. K. W. Kiel et al.
FUNGAL GENETICS AND BIOLOGY (2009)
Gene targeting in a nonhomologous end joining deficient Hypocrea jecorina
Zhang Guangtao et al.
JOURNAL OF BIOTECHNOLOGY (2009)
Acyltransferase Mediated Polyketide Release from a Fungal Megasynthase
Xinkai Xie et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Synthetic protein scaffolds provide modular control over metabolic flux
John E. Dueber et al.
NATURE BIOTECHNOLOGY (2009)
Heterologous production of non-ribosomal peptide LLD-ACV in Saccharomyces cerevisiae
Verena Siewers et al.
METABOLIC ENGINEERING (2009)
Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor
Diana M. Harris et al.
METABOLIC ENGINEERING (2009)
An Engineered Yeast Efficiently Secreting Penicillin
Loknath Gidijala et al.
PLOS ONE (2009)
Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans
Volker Schroeckh et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
A key role for vesicles in fungal secondary metabolism
Anindya Chanda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Complete Reconstitution of a Highly Reducing Iterative Polyketide Synthase
Suzanne M. Ma et al.
SCIENCE (2009)
Construction of a Citrinin Gene Cluster Expression System in Heterologous Aspergillus oryzae
Kanae Sakai et al.
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2008)
Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply
Songsak Wattanachaisaereekul et al.
METABOLIC ENGINEERING (2008)
A polyketide macrolactone synthase from the filamentous fungus Gibberella zeae
Hui Zhou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Improving simvastatin bioconversion in Escherichia coli by deletion of bioH
Xinkai Xie et al.
METABOLIC ENGINEERING (2007)
Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB
Suzanne M. Ma et al.
FEBS JOURNAL (2007)
Efficient synthesis of simvastatin by use of whole-cell biocatalysis
Xinkai Xie et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2007)
Genomics-driven discovery of PKS-NRPS hybrid metabolites from Aspergillus nidulans
Sebastian Bergmann et al.
NATURE CHEMICAL BIOLOGY (2007)
Highly efficient gene targeting in the Aspergillus niger kusA mutant
Vera Meyer et al.
JOURNAL OF BIOTECHNOLOGY (2007)
Catalytic relationships between type I and type II iterative polyketide synthases:: The Aspergillus parasiticus norsolorinic acid synthase
Yue Ma et al.
CHEMBIOCHEM (2006)
Identification of a starter unit acyl-carrier protein transacylase domain in an iterative type I polyketide synthase
Jason M. Crawford et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Biosynthesis of lovastatin analogs with a broadly specific acyltransferase
Xinkai Xie et al.
CHEMISTRY & BIOLOGY (2006)
A versatile and efficient gene-targeting system for Aspergillus nidulans
T Nayak et al.
GENETICS (2006)
Discovery of aspoquinolones A-D, prenylated quinoline-2-one alkaloids from Aspergillus nidulans, motivated by genome mining
Kirstin Scherlach et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
Fundamental contribution of β-oxidation to polyketide mycotoxin production in planta
LA Maggio-Hall et al.
MOLECULAR PLANT-MICROBE INTERACTIONS (2005)
Development of a novel quadruple auxotrophic host transformation system by argB gene disruption using adeA gene and exploiting adenine auxotrophy in Aspergillus oryzae
FH Jin et al.
FEMS MICROBIOLOGY LETTERS (2004)
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