Isolation and biological activity of azocine and azocane alkaloids

Thousands of known alkaloids contain a nitrogen (N) heterocycle. While five-, six- and seven-membered Nheterocycles (ie: pyrroles, imidazoles, indoles, pyridines and azepines and their saturated variants) are common, those with an eight-membered N-heterocycle are comparatively rare. This review discusses the structure and bioactivity of alkaloids that contain an azocine (or saturated azocane) ring, and the array of sources whence they originate.

Automated summary

This review discusses the structure and bioactivity of alkaloids that contain an eight-membered N-heterocycle, and their sources of origin.