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Recent advances in heat shock proteins in cancer diagnosis, prognosis, metabolism and treatment

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Summary: The heat shock protein superfamily, also known as molecular chaperones, are highly conserved and play vital roles in protein fate across all living organisms. Hsp70, a member of this superfamily, is expressed at low levels in normal cells but has been found to be overexpressed in various tumor cells, contributing to resistance to programmed cell death and tumor progression.

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